Is RESVERATROL safe to use in EU cosmetics?

RESVERATROL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 501-36-0?

CAS 501-36-0 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains RESVERATROL?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 5912615/10/2010

RESVERATROL

1,3-Benzenediol, 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-

RESVERATROL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 501-36-0

CAS 501-36-0PubChem CID 445154

Resveratrol

Resveratrol is a plant polyphenol found in high concentrations in red grapes that has been proposed as a treatment for hyperlipidemia and to prevent fatty liver, diabetes, atherosclerosis and aging. Resveratrol use has been associated with rare instances of serum enzyme elevations during therapy but has not been convincingly linked to episodes of clinically apparent liver injury. — LiverTox

IUPAC name: 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol

Molecular formula: C14H12O3
Molecular weight: 228.24 g/mol
Exact mass: 228.078644241 Da
XLogP3: 3.1
Topological polar surface area: 60.7 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

trans-resveratrol3,4',5-Trihydroxystilbene(E)-resveratrolResvida3,4',5-Stilbenetriol3,4',5-Trihydroxy-trans-stilbeneBiofortCuspidatin

16 more reported names

5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediolJotrolSRT-501(E)-5-(p-Hydroxystyryl)resorcinolResveratrol p 5SRT501Melinjo resveratrol 20Srt 501m5-[(E)-2-(4-hydroxyphenyl)vinyl]benzene-1,3-diolNSC-327430Q369O8926LCHEBI:27881CHEBI:45713Ca 1201BIA 6-512BIA-6-512

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:27881
ChEBI:CHEBI:45713
ChEMBL:CHEMBL165
EPA DTXSID:DTXSID4031980
PubMed:32020584
PubMed:29095837
PubMed:28883751
PubMed:28810692
PubMed:28338176
PubMed:26328004
PubMed:26099829
PubMed:25788047
PubMed:25701602
PubMed:25652123
PubMed:25525597
PubMed:25451966

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for RESVERATROL

INCI name

RESVERATROL

Description

1,3-Benzenediol, 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-

Record provenance

Inventory reference: 59126
Imported identity: RESVERATROL
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for RESVERATROL

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Key data

CAS

501-36-0

*610-504-8

Restriction

—

Function

ANTIOXIDANT: Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
SKIN PROTECTING: Helping to avoid harmful effects to the skin from external factors.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#24115 · RESVERATROL

Ingredients with overlapping formulation functions

RAPHANUS SATIVUS SPROUT JUICEANTIMICROBIAL, ANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING

RAPHANUS SATIVUS/TRIGONELLA FOENUM-GRAECUM/BRASSICA OLERACEA ITALICA SPROUT JUI…ANTIMICROBIAL, ANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING

RAVENALA MADAGASCARIENSIS ARIL EXTRACTSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

REHMANNIA ELATA ROOT EXTRACTSKIN PROTECTING

RESVERATRYL TRIACETATESKIN CONDITIONING, SKIN PROTECTING

RESVERATRYL TRIGLYCOLATESKIN CONDITIONING, SKIN PROTECTING

RESVERATRYL TRIS-HEXYLDECANOATEHAIR CONDITIONING; SKIN PROTECTING; SKIN CONDITIONING - MISCELLANEOUS

RETINOYL PENTAPEPTIDE-4SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How RESVERATROL appears in the CosIng inventory

The CosIng inventory lists RESVERATROL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

RESVERATROL is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

RESVERATROL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, RESVERATROL carries the following function designation(s):

CAS 501-36-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for RESVERATROL

This page reproduces the CosIng inventory entry for RESVERATROL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research RESVERATROL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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