Is LACTAMIDE safe to use in EU cosmetics?

LACTAMIDE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 2043-43-8?

CAS 2043-43-8 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains LACTAMIDE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 5784015/10/2010

LACTAMIDE

Propanamide, 2-hydroxy-

LACTAMIDE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 2043-43-8

CAS 2043-43-8PubChem CID 94220

Lactamide

Lactamide is a monocarboxylic acid amide that is lactic acid in which the carboxylic acid group has been converted to the corresponding carboxamide. It is a monocarboxylic acid amide and a secondary alcohol. It is functionally related to a rac-lactic acid. — ChEBI

IUPAC name: 2-hydroxypropanamide

Molecular formula: C3H7NO2
Molecular weight: 89.09 g/mol
Exact mass: 89.047678466 Da
XLogP3: -1.1
Topological polar surface area: 63.3 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

Propanamide, 2-hydroxy-2-HydroxypropionamideDL-LactamideLactic amideLactic acid amidealpha-Hydroxypropionamide4JZP7XJN3ONSC-9903

16 more reported names

NSC-61454CHEBI:75144RefChem:798348218-049-3.alpha.-Hydroxypropionamide(+/-)-lactamide2-hydroxy-propanamide2-hydroxy-propionamidealpha-hydroxypropanamideDL-Lactamide, 97%NSC9903EN300-72519DL-Lactic acid amideUNII-4JZP7XJN3OD,L-lactamideNSC 9903

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:75144
EPA DTXSID:DTXSID90862816
PubMed:22702807
PubMed:22334685
PubMed:22132857
PubMed:21520808
PubMed:21417248
PubMed:21202758
PubMed:21201860
PubMed:19496566
PubMed:19074156
PubMed:18446517
PubMed:17493132
PubMed:17347819

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for LACTAMIDE

INCI name

LACTAMIDE

Description

Propanamide, 2-hydroxy-

Record provenance

Inventory reference: 57840
Imported identity: LACTAMIDE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for LACTAMIDE

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Key data

CAS

2043-43-8

218-049-3

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#14264 · LACTAMIDE

Ingredients with overlapping formulation functions

LACSKIN CONDITIONING

LAC EXTRACTSKIN CONDITIONING

LAC POWDERSKIN CONDITIONING

LACHANCEA/HYDROLYZED RICE FERMENT FILTRATEHUMECTANT, SKIN CONDITIONING

LACTAMIDE DEASKIN CONDITIONING

LACTAMIDE MEAANTISTATIC, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING

LACTARIUS HATSUDAKE FRUITING BODY EXTRACTSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

LACTATE DEHYDROGENASESKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How LACTAMIDE appears in the CosIng inventory

The CosIng inventory lists LACTAMIDE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

LACTAMIDE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

LACTAMIDE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, LACTAMIDE carries the following function designation(s):

SKIN CONDITIONING

CAS 2043-43-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for LACTAMIDE

This page reproduces the CosIng inventory entry for LACTAMIDE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research LACTAMIDE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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