Is LACTAMIDE MEA safe to use in EU cosmetics?

LACTAMIDE MEA is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What function does LACTAMIDE MEA serve in cosmetics?

According to the EU CosIng inventory, LACTAMIDE MEA carries the following function designation(s): ANTISTATIC, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING.

What other records share CAS 5422-34-4?

CAS 5422-34-4 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains LACTAMIDE MEA?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3480715/10/2010

LACTAMIDE MEA

N-2-hydroxyethyllactamide

LACTAMIDE MEA is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 5422-34-4

CAS 5422-34-4PubChem CID 95457

N-(2-hydroxyethyl)lactamide

N-Lactoyl ethanolamine is a N-acylethanolamine. — ChEBI

IUPAC name: 2-hydroxy-N-(2-hydroxyethyl)propanamide

Molecular formula: C5H11NO3
Molecular weight: 133.15 g/mol
Exact mass: 133.07389321 Da
XLogP3: -1.4
Topological polar surface area: 69.6 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

2-LactamidoethanolRefChem:4733581-hydroxyethane-1-(2'-hydroxyethyl)carbonamideLactamide MEAPropanamide, 2-hydroxy-N-(2-hydroxyethyl)-n-lactoyl ethanolamineLactic acid monoethanolamideLactamide, N-(2-hydroxyethyl)-

16 more reported names

N-2-HydroxyethyllactamideN-HydroxyaethyllactamidCCRIS 3086Lipamide LMEAIncromectant LMEAN-beta-HydroxyethyllactamideNSC 11062Monoethanolamine lactic acid amideN-(beta-Hydroxyethyl)-2-hydroxypropionamideN-(.beta.-Hydroxyethyl)-2-hydroxypropionamideLACTOYL MONOETHANOLAMIDECHEBI:173359N-(.beta.-Hydroxyethyl)lactamide900T44YNC7NSC-11062AS-64098

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:173359
EPA DTXSID:DTXSID20863533
PubMed:20041445
PubMed:16548012

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for LACTAMIDE MEA

INCI name

LACTAMIDE MEA

Description

N-2-hydroxyethyllactamide

Record provenance

Inventory reference: 34807
Imported identity: LACTAMIDE MEA
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for LACTAMIDE MEA

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Key data

CAS

5422-34-4

226-546-1

Restriction

—

Function

ANTISTATIC: Preventing and/or reducing static electricity by neutralising electrical charge on surfaces.
HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
HUMECTANT: Retaining and/or preserving the moisture in a product during use.
SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#14266 · LACTAMIDE MEA

Ingredients with overlapping formulation functions

ISOTRIDECYL SALICYLATEANTISTATIC, SKIN CONDITIONING

JOJOBAMIDOPROPYL BETAINEABRASIVE, ANTISTATIC, CLEANSING, HAIR CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - FOAM BOOST…

JOJOBAMIDOPROPYL DIMETHYLAMINEANTISTATIC; SURFACTANT - EMULSIFYING; HAIR CONDITIONING

KERATIN AMINO ACIDSANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

LACTAMIDOPROPYL TRIMONIUM CHLORIDEANTISTATIC

LACTOBACILLUS/PRUNUS MUME FRUIT/LEAF/ROOT EXTRACT FERMENT FILTRATEANTISTATIC, SKIN CONDITIONING

LACTOBACILLUS/SACCHAROMYCES/MAGNOLIA OFFICINALIS BARK FERMENT EXTRACTANTISTATIC, SKIN CONDITIONING

LACTOGLOBULINANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How LACTAMIDE MEA appears in the CosIng inventory

The CosIng inventory lists LACTAMIDE MEA as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

LACTAMIDE MEA is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

LACTAMIDE MEA is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, LACTAMIDE MEA carries the following function designation(s):

CAS 5422-34-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for LACTAMIDE MEA

This page reproduces the CosIng inventory entry for LACTAMIDE MEA from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research LACTAMIDE MEA and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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