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CAS 526-99-8 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 5630415/10/2010

GALACTARIC ACID

1,2,3,4-Tetrahydroxy-1,4-butanedicarboxylic acid

GALACTARIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 526-99-8

CAS 526-99-8PubChem CID 3037582

Galactaric acid

Galactaric acid is a hexaric acid resulting from formal oxidative ring cleavage of galactose. It has a role as a human metabolite. It is a conjugate acid of a galactarate(1-) and a galactaric acid anion. — ChEBI

IUPAC name: (2S,3R,4S,5R)-2,3,4,5-tetrahydroxyhexanedioic acid

Molecular formula: C6H10O8
Molecular weight: 210.14 g/mol
Exact mass: 210.03756727 Da
XLogP3: -2.5
Topological polar surface area: 156.0 Å²
Hydrogen-bond donors: 6
Hydrogen-bond acceptors: 8
Covalent units: 1
Defined stereocentres: 4

Also known as

mucic acidSaccharolactic acidGalactosaccharic acid(2R,3S,4R,5S)-2,3,4,5-tetrahydroxyhexanedioic acidSchleimsaureMUCILIANCETetrahydroxyadipic acidE149J5OTIF

16 more reported names

NSC-81272R,3S,4R,5S-tetrahydroxy-hexanedioic acidCHEBI:308522,3,4,5-Tetrahydroxyhexanedioic acidstrontium galactarate mono-hydrateRefChem:633474GlyTouCan:G56286UC208-404-0D-Galactaric acidSchleimsaure [German]GalactarsaeureSchleimsaeureD-galactaratemeso-galactaric acidEINECS 208-404-0SCHEMBL5901

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:30852
ChEMBL:CHEMBL1232958
EPA DTXSID:DTXSID7048740
PubMed:22938926
PubMed:22922860
PubMed:22573318
PubMed:22554483
PubMed:22493433
PubMed:22427863
PubMed:22416247
PubMed:22316391
PubMed:22309085
PubMed:22301624
PubMed:22285512
PubMed:22239106

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for GALACTARIC ACID

INCI name

GALACTARIC ACID

Description

1,2,3,4-Tetrahydroxy-1,4-butanedicarboxylic acid

Record provenance

Inventory reference: 56304
Imported identity: GALACTARIC ACID
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for GALACTARIC ACID

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Key data

CAS

526-99-8

208-404-0

Restriction

—

Function

CHELATING: Forming complexes with metal ions which could affect the stability and/or appearance of cosmetics.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#10708 · GALACTARIC ACID

Ingredients with overlapping formulation functions

DISODIUM SALICYLPHOSPHATEANTIOXIDANT, CHELATING, SKIN CONDITIONING

DIVINYLDISILOXANECHELATING

EDTACHELATING

ETIDRONIC ACIDCHELATING

GALACTURONIC ACIDBUFFERING, CHELATING, HUMECTANT

GALLOYL TRIPEPTIDE-35ANTIOXIDANT, CHELATING, SKIN PROTECTING

GLUCONIC ACIDCHELATING, PERFUMING

GLUCONOLACTONECHELATING, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How GALACTARIC ACID appears in the CosIng inventory

The CosIng inventory lists GALACTARIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

GALACTARIC ACID is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

GALACTARIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, GALACTARIC ACID carries the following function designation(s):

CHELATING

CAS 526-99-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for GALACTARIC ACID

This page reproduces the CosIng inventory entry for GALACTARIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research GALACTARIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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