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InventoryRef 3375615/10/2010

EDTA

1,2-Ethanediamine, N,N,N',N'-tetrakis(carboxymethyl)-

EDTA is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 60-00-4
CAS 60-00-4PubChem CID 6049

Ethylenediaminetetraacetic Acid

Ethylenediaminetetraacetic acid is an ethylenediamine derivative, a tetracarboxylic acid and a polyamino carboxylic acid. It has a role as a copper chelator, a geroprotector, a calcium chelator, an antidote and an anticoagulant. It is a conjugate acid of an EDTA(2-). — ChEBI

IUPAC name
2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid
Molecular formula
C10H16N2O8
Molecular weight
292.24 g/mol
Exact mass
292.09066547 Da
XLogP3
-5.9
Topological polar surface area
156.0 Ų
Hydrogen-bond donors
4
Hydrogen-bond acceptors
10
Covalent units
1
Defined stereocentres
0

Also known as

EDTAEdetic acidEdathamilSequestrolHavidoteTitriplexCheeloxEDTA acid
16 more reported names
Sequestrene aaVersene acidTrilon BSGluma cleanserSequestric acidWarkeelate acidKomplexon iiTetrine acidQuastal SpecialMetaquest ATrilon bw(Ethylenedinitrilo)tetraacetic acidTitriplex IICheelox BF acidCelon ACelon ATH
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for EDTA

INCI name

EDTA

INN name

edetic acid

Description

1,2-Ethanediamine, N,N,N',N'-tetrakis(carboxymethyl)-

Record provenance

Inventory reference
33756
Imported identity
EDTA
Source update
15/10/2010
European Commission CosIng source notes
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Key data

CAS
60-00-4
EC
200-449-4
Restriction
—
Function
CHELATING
Forming complexes with metal ions which could affect the stability and/or appearance of cosmetics.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#9726 · EDTA

Ingredients with overlapping formulation functions

DISODIUM LAURYLGLUCOSIDES HYDROXYPROPYL CITRATECHELATING, CLEANSING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING, SURFACTANT - FOAM BOOS…
DISODIUM PYROPHOSPHATEANTICORROSIVE, BUFFERING, CHELATING
DISODIUM SALICYLPHOSPHATEANTIOXIDANT, CHELATING, SKIN CONDITIONING
DIVINYLDISILOXANECHELATING
ETIDRONIC ACIDCHELATING
GALACTARIC ACIDCHELATING
GALACTURONIC ACIDBUFFERING, CHELATING, HUMECTANT
GALLOYL TRIPEPTIDE-35ANTIOXIDANT, CHELATING, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How EDTA appears in the CosIng inventory

The CosIng inventory lists EDTA as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

EDTA is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

EDTA is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, EDTA carries the following function designation(s):

CAS 60-00-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for EDTA

This page reproduces the CosIng inventory entry for EDTA from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research EDTA and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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