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InventoryRef 5619915/10/2010

GLYCEROPHOSPHOCHOLINE

Ethanaminium, 2,[[[(2R)-2,3-Dihydroxypropoxy] Hydroxyphosphinyl]Oxy]-N,N,N,-Trimethyl-, Inner Salt

GLYCEROPHOSPHOCHOLINE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 28319-77-9
CAS 28319-77-9PubChem CID 657272

Choline Alfoscerate

Choline alfoscerate is a member of the class of phosphocholines that is the choline ester of sn-glycero-3-phosphate. It is one of the major osmolyte in the renal medullary cells. It has a role as a parasympatholytic, a neuroprotective agent, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is a member of sn-glycerol 3-phosphates and a member of phosphocholines. — ChEBI

IUPAC name
[(2R)-2,3-dihydroxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
Molecular formula
C8H20NO6P
Molecular weight
257.22 g/mol
Exact mass
257.10282436 Da
XLogP3
-2.3
Topological polar surface area
99.1 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
1

Also known as

SN-glycero-3-phosphocholineCholine glycerophosphateL-alpha-GlycerophosphorylcholineGlycerophosphorylcholineL-alpha-GlycerophosphocholineCholine AlphoscerateGPChoCholini glycerophosphas
16 more reported names
Cholini alfoscerasGlicerofosfato de colinaalpha-GlycerophosphorylcholineAlfoscerato de colinaGlycerophosphate de cholineAlfoscerate de cholinealpha-GlycerylphosphorylcholineGlycerol phosphorylcholineSn-3-GPCglycerol-3-phosphocholineGlycerol-3-phosphatidylcholineGliatilinCHEBI:1687060M22SGW66(2R)-2,3-dihydroxypropyl 2-(trimethylammonio)ethyl phosphateL-1-glycero-3-phosphocholine
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for GLYCEROPHOSPHOCHOLINE

INCI name

GLYCEROPHOSPHOCHOLINE

INN name

cholin alfoscerate

Description

Ethanaminium, 2,[[[(2R)-2,3-Dihydroxypropoxy] Hydroxyphosphinyl]Oxy]-N,N,N,-Trimethyl-, Inner Salt

Record provenance

Inventory reference
56199
Imported identity
GLYCEROPHOSPHOCHOLINE
Source update
15/10/2010
European Commission CosIng source notes

Key data

Restriction
—
Function
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How GLYCEROPHOSPHOCHOLINE appears in the CosIng inventory

The CosIng inventory lists GLYCEROPHOSPHOCHOLINE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

GLYCEROPHOSPHOCHOLINE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

GLYCEROPHOSPHOCHOLINE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, GLYCEROPHOSPHOCHOLINE carries the following function designation(s):

CAS 28319-77-9 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for GLYCEROPHOSPHOCHOLINE

This page reproduces the CosIng inventory entry for GLYCEROPHOSPHOCHOLINE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research GLYCEROPHOSPHOCHOLINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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