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EU cosmetic ingredients, restrictions and safety
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Official EU label nameGlossary entry 11111

GLYCEROPHOSPHOCHOLINE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
2

Resolved substance identity

CAS:28319-77-9
EC:248-962-2
Ingredient index records:
GLYCEROPHOSPHOCHOLINE
Cosmetic functions: SKIN CONDITIONING

Ethanaminium, 2,[[[(2R)-2,3-Dihydroxypropoxy] Hydroxyphosphinyl]Oxy]-N,N,N,-Trimethyl-, Inner Salt

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2 matched or reported names
GLYCEROPHOSPHOCHOLINEcholin alfoscerate

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name GLYCEROPHOSPHOCHOLINE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 28319-77-9
CAS 28319-77-9PubChem CID 657272

Choline Alfoscerate

Choline alfoscerate is a member of the class of phosphocholines that is the choline ester of sn-glycero-3-phosphate. It is one of the major osmolyte in the renal medullary cells. It has a role as a parasympatholytic, a neuroprotective agent, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is a member of sn-glycerol 3-phosphates and a member of phosphocholines. — ChEBI

IUPAC name
[(2R)-2,3-dihydroxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
Molecular formula
C8H20NO6P
Molecular weight
257.22 g/mol
Exact mass
257.10282436 Da
XLogP3
-2.3
Topological polar surface area
99.1 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
1

Also known as

SN-glycero-3-phosphocholineCholine glycerophosphateL-alpha-GlycerophosphorylcholineGlycerophosphorylcholineL-alpha-GlycerophosphocholineCholine AlphoscerateGPChoCholini glycerophosphas
16 more reported names
Cholini alfoscerasGlicerofosfato de colinaalpha-GlycerophosphorylcholineAlfoscerato de colinaGlycerophosphate de cholineAlfoscerate de cholinealpha-GlycerylphosphorylcholineGlycerol phosphorylcholineSn-3-GPCglycerol-3-phosphocholineGlycerol-3-phosphatidylcholineGliatilinCHEBI:1687060M22SGW66(2R)-2,3-dihydroxypropyl 2-(trimethylammonio)ethyl phosphateL-1-glycero-3-phosphocholine
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External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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