Is 1,2-HEXANEDIOL safe to use in EU cosmetics?

1,2-HEXANEDIOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 6920-22-5?

CAS 6920-22-5 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains 1,2-HEXANEDIOL?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 5417016/05/2019

1,2-HEXANEDIOL

1,2-HEXANEDIOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 6920-22-5

CAS 6920-22-5PubChem CID 94335

1,2-Hexanediol

IUPAC name: hexane-1,2-diol

Molecular formula: C6H14O2
Molecular weight: 118.17 g/mol
Exact mass: 118.099379685 Da
XLogP3: 0.7
Topological polar surface area: 40.5 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

DL-1,2-Hexanediol1,2-Dihydroxyhexane5,6-DihydroxyhexaneTR046Y3K1GRefChem:412076230-029-6dl-hexane-1,2-diol1,2-Hexylene Glycol

14 more reported names

UNII-TR046Y3K1G(+/-)-Hexane-1,2-diol; 1,2-Dihydroxyhexane; 1,2-Hexyleneglycol; 5,6-Dihydroxyhexane; DL-1,2-Hexanediol; KMO 61,2-hexyleneglycolEINECS 230-029-6AI3-13210(2R)-1,2-Hexanediol1,2-Hexanediol, 98%EC 230-029-61,2-hexanediol [WHO-DD]1,2-HEXANEDIOL, DLCS-W013596DS-7407H0688EN300-1678327

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID40863959
PubMed:22883556
PubMed:21669264
PubMed:21585401
PubMed:21111167
PubMed:19778027
PubMed:19693757
PubMed:19514921
PubMed:17618070
PubMed:17270720
PubMed:16256492
PubMed:15296184
PubMed:12526827

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for 1,2-HEXANEDIOL

INCI name

1,2-HEXANEDIOL

Record provenance

Inventory reference: 54170
Imported identity: 1,2-HEXANEDIOL
Source update: 16/05/2019

European Commission CosIng source notes

Annex records for 1,2-HEXANEDIOL

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Key data

CAS

6920-22-5

230-029-6

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.
SOLVENT: Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#107 · 1,2-HEXANEDIOL

Ingredients with overlapping formulation functions

1,10-DECANEDIOLSOLVENT

1,2,6-HEXANETRIOLHUMECTANT, SOLVENT, VISCOSITY CONTROLLING

1,2-BUTANEDIOLHUMECTANT, SKIN CONDITIONING, SOLVENT, VISCOSITY CONTROLLING

1,4-BUTANEDIOLSOLVENT

1,5-PENTANEDIOLSOLVENT

1-NITROPROPANESOLVENT

2,3-BUTANEDIOLFRAGRANCE, HUMECTANT, SKIN CONDITIONING, SOLVENT

2-ETHYLHEXYLALSOLVENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How 1,2-HEXANEDIOL appears in the CosIng inventory

The CosIng inventory lists 1,2-HEXANEDIOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

1,2-HEXANEDIOL is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

1,2-HEXANEDIOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, 1,2-HEXANEDIOL carries the following function designation(s):

CAS 6920-22-5 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for 1,2-HEXANEDIOL

This page reproduces the CosIng inventory entry for 1,2-HEXANEDIOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research 1,2-HEXANEDIOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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