Is 1,2-BUTANEDIOL safe to use in EU cosmetics?

1,2-BUTANEDIOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What function does 1,2-BUTANEDIOL serve in cosmetics?

According to the EU CosIng inventory, 1,2-BUTANEDIOL carries the following function designation(s): HUMECTANT, SKIN CONDITIONING, SOLVENT, VISCOSITY CONTROLLING.

What other records share CAS 584-03-2?

CAS 584-03-2 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains 1,2-BUTANEDIOL?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 5416915/10/2010

1,2-BUTANEDIOL

1,2-BUTANEDIOL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 584-03-2

CAS 584-03-2PubChem CID 11429

1,2-Butanediol

Butane-1,2-diol is a butanediol in which the two hydroxy groups are located at positions 1 and 2. It has a role as a metabolite. It is a glycol and a butanediol. — ChEBI

IUPAC name: butane-1,2-diol

Molecular formula: C4H10O2
Molecular weight: 90.12 g/mol
Exact mass: 90.068079557 Da
XLogP3: -0.2
Topological polar surface area: 40.5 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

1,2-Butylene glycol1,2-Dihydroxybutanealpha-Butylene glycolalpha-ButyleneglycolRUN0H01QEUNSC-24242CHEBI:52682Massage Oil

16 more reported names

RefChem:934958209-527-2Butanediol, 1,2-1,2-(Dihydroxy)butane1,2-ButandiolDL-1,2-ButanediolNSC 24242.alpha.-Butylene glycolHSDB 1507EINECS 209-527-2UNII-RUN0H01QEUBRN 0969169AI3-07554butanol-2-ol(+/-)-BUTANE-1,2-DIOL1,2-butylene-glycol

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:52682
EPA DTXSID:DTXSID6040375
PubMed:22719538
PubMed:22126977
PubMed:21912747
PubMed:21720824
PubMed:21339957
PubMed:21304735
PubMed:21211801
PubMed:20856881
PubMed:20825169
PubMed:20533069
PubMed:20095595
PubMed:19845315

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for 1,2-BUTANEDIOL

INCI name

1,2-BUTANEDIOL

Record provenance

Inventory reference: 54169
Imported identity: 1,2-BUTANEDIOL
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for 1,2-BUTANEDIOL

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Key data

CAS

584-03-2

209-527-2

Restriction

—

Function

HUMECTANT: Retaining and/or preserving the moisture in a product during use.
SKIN CONDITIONING: Maintaining the skin in good condition.
SOLVENT: Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).
VISCOSITY CONTROLLING: Increasing or decreasing the viscosity (thickness) of cosmetics.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#104 · 1,2-BUTANEDIOL

Ingredients with overlapping formulation functions

1,10-DECANEDIOLSOLVENT

1,2,6-HEXANETRIOLHUMECTANT, SOLVENT, VISCOSITY CONTROLLING

1,2-HEXANEDIOLSKIN CONDITIONING, SOLVENT

1,4-BUTANEDIOLSOLVENT

1,5-PENTANEDIOLSOLVENT

1-NITROPROPANESOLVENT

2,3-BUTANEDIOLFRAGRANCE, HUMECTANT, SKIN CONDITIONING, SOLVENT

2-ETHYLHEXYLALSOLVENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How 1,2-BUTANEDIOL appears in the CosIng inventory

The CosIng inventory lists 1,2-BUTANEDIOL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

1,2-BUTANEDIOL is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

1,2-BUTANEDIOL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, 1,2-BUTANEDIOL carries the following function designation(s):

CAS 584-03-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for 1,2-BUTANEDIOL

This page reproduces the CosIng inventory entry for 1,2-BUTANEDIOL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research 1,2-BUTANEDIOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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