ACID YELLOW 73
3',6''-Dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]Xanthen]-3-one (CI 45350:1); 2-(6-Hydroxy-3-oxo-(3H)-xanthen-9-yl)benzoic acid
ACID YELLOW 73 is linked to 2 EU annex records on this page. Inventory note: II/1332 (when used as a substance in hair dye products).
Regulatory evidence by market
This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.
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| Market | Evidence status | Records | Source language |
|---|---|---|---|
| European Union | Evidence linked Prohibited entry found Open this evidence | 2 | English and EU languages |
| Great Britain | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Canada | Source mapped Official source mapped; ingredient rule not imported | 0 | English and French |
| New Zealand | Evidence linked Prohibited Open this evidence | 1 | English |
| ASEAN | Evidence linked Prohibited Open this evidence | 1 | English and national languages |
| China | Source mapped Official source mapped; ingredient rule not imported | 0 | Chinese with selected English material |
| Japan | Source mapped Official source mapped; ingredient rule not imported | 0 | Japanese; official English translation available |
| South Korea | Source mapped Official source mapped; ingredient rule not imported | 0 | Korean with some English names |
| United States | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Australia | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Brazil | Evidence linked Prohibited Open this evidence | 1 | Portuguese with INCI crosswalks |
| India | Evidence linked Prohibited Open this evidence | 1 | English and Hindi |
| Saudi Arabia | Evidence linked Prohibited Open this evidence | 1 | Arabic and English |
Chemical identity and properties
Fluorescein
Fluorescein (lactone form) is a xanthene dye that is highly fluorescent, detectable even when present in minute quantities. Used forensically to detect traces of blood, in analytical chemistry as an indicator in silver nitrate titrations and in microscopy. It has a role as a radioopaque medium and a fluorescent dye. It is a polyphenol, a gamma-lactone, a xanthene dye, an oxaspiro compound, an organic heteropentacyclic compound and a member of 2-benzofurans. It is functionally related to a fluorescein (acid form). — ChEBI
- IUPAC name
- 3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
- Molecular formula
- C20H12O5
- Molecular weight
- 332.3 g/mol
- Exact mass
- 332.06847348 Da
- XLogP3
- 3.4
- Topological polar surface area
- 76.0 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 5
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:31624
- ChEMBL:CHEMBL1057
- EPA DTXSID:DTXSID0038887
- PubMed:23120194
- PubMed:23115148
- PubMed:23109801
- PubMed:23106861
- PubMed:23105641
- PubMed:23096146
- PubMed:23093817
- PubMed:23091763
- PubMed:23091408
- PubMed:23084247
- PubMed:23083196
- PubMed:23080316
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for ACID YELLOW 73
INCI name
ACID YELLOW 73
Description
3',6''-Dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]Xanthen]-3-one (CI 45350:1); 2-(6-Hydroxy-3-oxo-(3H)-xanthen-9-yl)benzoic acid
Record provenance
- Inventory reference
- 54164
- Imported identity
- ACID YELLOW 73
- Source update
- 12/08/2020
Annex records for ACID YELLOW 73
2-(6-Hydroxy-3-oxo-(3H)xanthen-9-yl)benzoic acid; Fluorescein and its disodium salt (Acid Yellow 73…
Key data
- COLORANT
- Exclusively or mainly intended to colour the cosmetic product, the body as a whole or certain parts thereof, by absorption or reflection of visible light. All authorised colorants are substances in the positive list of Annex IV to the Cosmetics Regulation 1223/2009.
- HAIR DYEING
- Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How ACID YELLOW 73 appears in the CosIng inventory
The CosIng inventory lists ACID YELLOW 73 as a cosmetic ingredient and this page links it to 2 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
ACID YELLOW 73 is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for ACID YELLOW 73
This page combines the CosIng inventory entry for ACID YELLOW 73 with 2 linked Annex II–VI records from the local dataset built from public European Commission cosmetic ingredient materials.
Use this inventory page to research ACID YELLOW 73 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
Tools & next steps
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