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InventoryRef 4146002/03/2011

NERAL

(Z)-3,7-Dimethylocta-2,6-dienal

NERAL is linked to 1 EU annex record on this page.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Restricted entry found
Open this evidence		1English and EU languages
Great BritainSource mapped
Official source mapped; ingredient rule not imported
0English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandSource mapped
Official source mapped; ingredient rule not imported
0English
ASEANSource mapped
Official source mapped; ingredient rule not imported
0English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaSource mapped
Official source mapped; ingredient rule not imported
0English and Hindi
Saudi ArabiaSource mapped
Official source mapped; ingredient rule not imported
0Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 106-26-3
CAS 106-26-3PubChem CID 643779

Neral

Neral is an enal that is 3,7-dimethyloctanal with unsaturation at positions C-2 and C-6. It has been isolated form the essential oils of plant species like lemon. It has a role as an apoptosis inducer and a plant metabolite. It is a monoterpenoid and an enal. — ChEBI

IUPAC name
(2Z)-3,7-dimethylocta-2,6-dienal
Molecular formula
C10H16O
Molecular weight
152.23 g/mol
Exact mass
152.120115130 Da
XLogP3
3.0
Topological polar surface area
17.1 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Covalent units
1
Defined stereocentres
0

Also known as

cis-CitralCitral b(Z)-Citrallemonal2,6-Octadienal, 3,7-dimethyl-, (2Z)-8M466BQL1XCHEBI:29020RefChem:44035
16 more reported names
203-379-2(Z)-3,7-Dimethylocta-2,6-dienalbeta-Citral(Z)-NeralNeroli aldehyde2,6-Octadienal, 3,7-dimethyl-, (Z)-.beta.-CitralZ-Citral2,6-Octadienal,3,7-dimethyl-, (2Z)-cis-3,7-Dimethyl-2,6-octadienalcitral-b(Z)-3,7-Dimethyl-2,6-octadienalUNII-8M466BQL1X(Z)-alpha-citralEINECS 203-379-2cis-Citral (Neral)
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:29020

neral

An enal that is 3,7-dimethyloctanal with unsaturation at positions C-2 and C-6. It has been isolated form the essential oils of plant species like lemon.

Formula
C10H16O
Average mass
152.237 g/mol
Monoisotopic mass
152.12012 Da
Formal charge
0
  • enal — is a (CHEBI:51688)
  • monoterpenoid — is a (CHEBI:25409)
  • apoptosis inducer — has role (CHEBI:68495)
  • plant metabolite — has role (CHEBI:76924)
  • apoptosis inducer — has role (CHEBI:68495)
  • plant metabolite — has role (CHEBI:76924)
  • enal — is a (CHEBI:51688)
  • monoterpenoid — is a (CHEBI:25409)
Additional curated names
(2Z)-3,7-dimethylocta-2,6-dienalcis-citralcis-Citralcitral BLemonalNeral
Cross-references from this source

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2019-06-18. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match643779

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H319 (62.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P264+P265, P272, P280, P302+P352, P305+P351+P338, P321, P332+P317, P333+P317, P337+P317, P362+P364, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 294 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • GHS Hazard Statements: H315: Causes skin irritation [Warning Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Precautionary Statement Codes: P261, P264, P272, P280, P302+P352, P321, P332+P317, P333+P317, P362+P364, and P501 (click each P-code to see the statement) Source: Hazardous Chemical Information System (HCIS), Safe Work Australia

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for NERAL

INCI name

NERAL

Description

(Z)-3,7-Dimethylocta-2,6-dienal

Record provenance

Inventory reference
41460
Imported identity
NERAL
Source update
02/03/2011
European Commission CosIng source notes
Annex III Shared CAS number
Entry 70

Citral; Geranial; Neral

CAS: 5392-40-5; 141-27-5; 106-26-3
EC: 226-394-6; 205-476-5; 203-379-2

Key data

CAS
106-26-3
EC
203-379-2
Restriction
—
Function
PERFUMING
Used for perfume and aromatic raw materials.

Ingredients with overlapping formulation functions

NEOMENTHOLPERFUMING
NEOPENTANAL BUTENYLENEGLYCOL ACETALPERFUMING
NEPETA CATARIA FLOWER EXTRACTPERFUMING
NEPETA CATARIA OILFRAGRANCE, PERFUMING
NEROLPERFUMING
NEROL OXIDEPERFUMING
NEROLIDOLPERFUMING
NEROLIDOL ISOMERSPERFUMING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How NERAL appears in the CosIng inventory

The CosIng inventory lists NERAL as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

NERAL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

NERAL appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

According to the EU CosIng inventory, NERAL carries the following function designation(s):

CAS 106-26-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for NERAL

This page combines the CosIng inventory entry for NERAL with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research NERAL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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