What does the restriction note for GAMMA-TERPINENE mean?

The restriction field for GAMMA-TERPINENE reads: III/132. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 99-85-4?

CAS 99-85-4 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains GAMMA-TERPINENE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 4143515/10/2010

GAMMA-TERPINENE

p-Mentha-1,4-diene; 1-Methyl-4-isopropyl-1,4-cyclohexadiene; 1-Methyl-4-(1-methylethyl)-1,4-cyclohexadiene

GAMMA-TERPINENE is linked to 1 EU annex record on this page. Inventory note: III/132.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Restricted entry found Open this evidence	1	English and EU languages
Great Britain	Evidence linked Restricted Open this evidence	1	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Restricted Open this evidence	1	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Evidence linked Prohibited Open this evidence	1	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Evidence linked Restricted Open this evidence	1	English and Hindi
Saudi Arabia	Evidence linked Restricted Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 99-85-4

CAS 99-85-4PubChem CID 7461

Gamma-Terpinene

Gamma-terpinene is one of three isomeric monoterpenes differing in the positions of their two double bonds (alpha- and beta-terpinene being the others). In gamma-terpinene the double bonds are at the 1- and 4-positions of the p-menthane skeleton. It has a role as an antioxidant, a volatile oil component, a plant metabolite and a human xenobiotic metabolite. It is a monoterpene and a cyclohexadiene. — ChEBI

IUPAC name: 1-methyl-4-propan-2-ylcyclohexa-1,4-diene

Molecular formula: C10H16
Molecular weight: 136.23 g/mol
Exact mass: 136.125200510 Da
XLogP3: 2.8
Topological polar surface area: 0.0 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 0
Covalent units: 1
Defined stereocentres: 0

Also known as

p-Mentha-1,4-dieneCrithmeneMoslenegamma-Terpinen4-Isopropyl-1-methyl-1,4-cyclohexadiene1,4-p-Menthadiene1-Isopropyl-4-methyl-1,4-cyclohexadiene1,4-Cyclohexadiene, 1-methyl-4-(1-methylethyl)-

16 more reported names

1-Methyl-4-(1-methylethyl)-1,4-cyclohexadiene1-methyl-4-(propan-2-yl)cyclohexa-1,4-diene1-isopropyl-4-methylcyclohexa-1,4-dieneFEMA No. 35594YGF4PQP49NSC-21448CHEBI:105771-methyl-4-[1-methylethyl]-1,4-cyclohexadieneRefChem:5852202-794-6.gamma.-Terpinen.gamma.-TerpineneTERPINENE, ALPHAg-Terpinene1-Methyl-4-isopropylcyclohexadiene-1,4NSC 21448

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:10577
ChEMBL:CHEMBL449693
EPA DTXSID:DTXSID6041210
PubMed:23018851
PubMed:22908589
PubMed:22799104
PubMed:22645427
PubMed:22606841
PubMed:22538487
PubMed:22514885
PubMed:22432633
PubMed:22428263
PubMed:22394020
PubMed:22372143
PubMed:22303071

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for GAMMA-TERPINENE

INCI name

GAMMA-TERPINENE

Description

p-Mentha-1,4-diene; 1-Methyl-4-isopropyl-1,4-cyclohexadiene; 1-Methyl-4-(1-methylethyl)-1,4-cyclohexadiene

Record provenance

Inventory reference: 41435
Imported identity: GAMMA-TERPINENE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for GAMMA-TERPINENE

Annex III Restriction reference

Entry 132

gamma-Terpinene; p-Mentha-1,4-diene

CAS: 99-85-4

EC: 202-794-6

Key data

CAS

99-85-4

202-794-6

Restriction

III/132

Function

PERFUMING: Used for perfume and aromatic raw materials.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#10772 · GAMMA-TERPINENE

The markets do not agree about this substance: it is prohibited in some and permitted under conditions in others, across the 6 markets that hold a rule for it.

prohibited: South Korea
restricted: European Union Great Britain New Zealand India Saudi Arabia

See every substance the markets disagree about

Ingredients with overlapping formulation functions

GAMMA-METHYLDECALACTONEPERFUMING

GAMMA-METHYLENEDIHYDROCINNAMYL ACETATEPERFUMING

GAMMA-NONALACTONEFRAGRANCE, PERFUMING, SKIN CONDITIONING

GAMMA-OCTALACTONEPERFUMING

GAMMA-UNDECALACTONEPERFUMING, SKIN CONDITIONING

GAMMA-VALEROLACTONEPERFUMING

GAULTHERIA PROCUMBENS LEAF EXTRACTPERFUMING, SKIN CONDITIONING, TONIC

GAULTHERIA PROCUMBENS LEAF OILFRAGRANCE, PERFUMING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How GAMMA-TERPINENE appears in the CosIng inventory

The CosIng inventory lists GAMMA-TERPINENE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

GAMMA-TERPINENE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

GAMMA-TERPINENE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for GAMMA-TERPINENE reads: "III/132". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, GAMMA-TERPINENE carries the following function designation(s):

PERFUMING

CAS 99-85-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for GAMMA-TERPINENE

This page combines the CosIng inventory entry for GAMMA-TERPINENE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research GAMMA-TERPINENE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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