GAMMA-OCTALACTONE
Octan-4-olide
GAMMA-OCTALACTONE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.
Regulatory evidence by market
No rule for this ingredient has been imported for any of the 13 markets tracked here.
That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.
Chemical identity and properties
gamma-Octalactone
Gamma-octalactone is a gamma-lactone that is oxolan-2-one substituted by a butyl group at position 5. It is a volatile compound found in peaches, mangoes, beef and ham. It has a role as an insect attractant, a flavouring agent, a mammalian metabolite, a mouse metabolite, a plant metabolite and a fungal metabolite. It is a volatile organic compound, a gamma-lactone and a tetrahydrofuranone. — ChEBI
- IUPAC name
- 5-butyloxolan-2-one
- Molecular formula
- C8H14O2
- Molecular weight
- 142.20 g/mol
- Exact mass
- 142.099379685 Da
- XLogP3
- 1.6
- Topological polar surface area
- 26.3 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 2
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:145738
- ChEMBL:CHEMBL3559967
- EPA DTXSID:DTXSID1047609
- PubMed:21823126
- PubMed:21535590
- PubMed:20415420
- PubMed:19390894
- PubMed:19228057
- PubMed:19154158
- PubMed:16233291
- PubMed:15453696
- PubMed:15137852
- PubMed:12862384
Evidence from additional scientific databases
EMBL-EBI ChEBI
γ-octalactone
A γ-lactone that is oxolan-2-one substituted by a butyl group at position 5. It is a volatile compound found in peaches, mangoes, beef and ham.
- Formula
- C8H14O2
- Average mass
- 142.198 g/mol
- Monoisotopic mass
- 142.09938 Da
- Formal charge
- 0
- volatile organic compound — is a (CHEBI:134179)
- γ-lactone — is a (CHEBI:37581)
- tetrahydrofuranone — is a (CHEBI:47016)
- fungal metabolite — has role (CHEBI:76946)
- mouse metabolite — has role (CHEBI:75771)
- mammalian metabolite — has role (CHEBI:75768)
- insect attractant — has role (CHEBI:24850)
- plant metabolite — has role (CHEBI:76924)
- flavouring agent — has role (CHEBI:35617)
- fungal metabolite — has role (CHEBI:76946)
- mouse metabolite — has role (CHEBI:75771)
- mammalian metabolite — has role (CHEBI:75768)
- insect attractant — has role (CHEBI:24850)
- plant metabolite — has role (CHEBI:76924)
- flavouring agent — has role (CHEBI:35617)
- volatile organic compound — is a (CHEBI:134179)
- γ-lactone — is a (CHEBI:37581)
- tetrahydrofuranone — is a (CHEBI:47016)
Additional curated names
Cross-references from this source
- CAS: 104-50-7 — ChemIDplus
- CAS: 104-50-7 — NIST Chemistry WebBook
- REGISTRY_NUMBER: 111677 — Reaxys
- MANUAL_X_REF: FDB014100 — FooDB
- MANUAL_X_REF: HMDB0035422 — HMDB
- MANUAL_X_REF: LMFA07040016 — LIPID MAPS
Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2020-01-07. Retrieved: 2026-08-31. Open source record
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Boiling Point: 234.00 °C. @ 760.00 mm Hg Source: Human Metabolome Database (HMDB)
- Boiling Point: 234 °C Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Density: 0.970-0.980 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Physical Description: CBI; Liquid Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Colorless liquid; [Alfa Aesar MSDS] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: colourless to slightly yellow liquid with a sweet, coconut, fruity odour Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Refractive Index: 1.443-1.447 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: slightly Source: Human Metabolome Database (HMDB)
- Solubility: soluble in alcohol and slightly soluble in water Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: (in ethanol) Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Note: This chemical does not meet GHS hazard criteria for 92.8% (1616 of 1742) of all reports. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 1616 of 1742 companies (only 7.2% companies provided GHS information). For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 1742 reports by companies from 9 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 1616 of 1742 reports by companies.; There are 7 notifications provided by 126 of 1742 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Consumer Uses: Fragrance Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Fragrance Source: EPA Chemical Data Reporting (CDR)
- Sources/Uses: Used as flavoring agent or adjuvant; [FDA] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| EMBL-EBI ChEBI | Exact match | 2026-08-31 |
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for GAMMA-OCTALACTONE
INCI name
GAMMA-OCTALACTONE
Description
Octan-4-olide
Record provenance
- Inventory reference
- 40517
- Imported identity
- GAMMA-OCTALACTONE
- Source update
- 02/03/2011
Annex records for GAMMA-OCTALACTONE
Key data
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How GAMMA-OCTALACTONE appears in the CosIng inventory
The CosIng inventory lists GAMMA-OCTALACTONE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
GAMMA-OCTALACTONE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for GAMMA-OCTALACTONE
This page reproduces the CosIng inventory entry for GAMMA-OCTALACTONE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.
Use this inventory page to research GAMMA-OCTALACTONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
Tools & next steps
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