GAMMA-VALEROLACTONE
Dihydro-5-methyl-2(3H)-furanone; gamma-Valerolactone
GAMMA-VALEROLACTONE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.
Regulatory evidence by market
No rule for this ingredient has been imported for any of the 13 markets tracked here.
That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.
Chemical identity and properties
Gamma-Valerolactone
Gamma-valerolactone is a clear, colorless, mobile liquid. pH (anhydrous): 7.0. pH (10% solution in distilled water): 4.2. (NTP, 1992) — CAMEO Chemicals
- IUPAC name
- 5-methyloxolan-2-one
- Molecular formula
- C5H8O2
- Molecular weight
- 100.12 g/mol
- Exact mass
- 100.052429494 Da
- XLogP3
- 0.6
- Topological polar surface area
- 26.3 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 2
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:48569
- ChEMBL:CHEMBL195593
- EPA DTXSID:DTXSID0047618
- PubMed:23486087
- PubMed:22507905
- PubMed:22349589
- PubMed:22137345
- PubMed:22105964
- PubMed:22005944
- PubMed:21786816
- PubMed:21732502
- PubMed:21580698
- PubMed:21535802
- PubMed:21394926
- PubMed:21389610
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Boiling Point: 405 to 406 °F at 760 mmHg (NTP, 1992) Source: CAMEO Chemicals
- Boiling Point: 207.00 to 208.00 °C. @ 760.00 mm Hg Source: Human Metabolome Database (HMDB)
- Boiling Point: 207 °C Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Density: 1.057 at 68 °F (NTP, 1992) - Denser than water; will sink Source: CAMEO Chemicals
- Density: 1.047-1.054 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Flash Point: 178 °F (NTP, 1992) Source: CAMEO Chemicals
- LogP: -0.270 Source: Human Metabolome Database (HMDB)
- Melting Point: -24 °F (NTP, 1992) Source: CAMEO Chemicals
- Melting Point: -31 °C Source: Human Metabolome Database (HMDB)
- Physical Description: Gamma-valerolactone is a clear, colorless, mobile liquid. pH (anhydrous): 7.0. pH (10% solution in distilled water): 4.2. (NTP, 1992) Source: CAMEO Chemicals
- Physical Description: Colorless liquid; [CAMEO] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: Liquid Source: Human Metabolome Database (HMDB)
- Physical Description: colourless to slightly yellow liquid with a warm, sweet, herbaceous odour Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Refractive Index: 1.431-1.434 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: greater than or equal to 100 mg/mL at 72 °F (NTP, 1992) Source: CAMEO Chemicals
- Solubility: miscible with alcohol, most fixed oils and water Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: (in ethanol) Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Vapor Pressure: 0.5 mmHg at 84 °F ; 3.5 mmHg at 124 °F; 11.5 mmHg at 163 °F (NTP, 1992) Source: CAMEO Chemicals
- First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
- Note: This chemical does not meet GHS hazard criteria for 96.7% (1420 of 1469) of all reports. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 1420 of 1469 companies (only 3.3% companies provided GHS information). For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 1469 reports by companies from 9 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 1420 of 1469 reports by companies.; There are 7 notifications provided by 49 of 1469 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Sources/Uses: A metabolite of n-hexane; [ChemIDplus] Used as flavoring agent or adjuvant; [FDA] A constituent of crude polyligneous acid; Used in dye bathes (coupling agent), brake fluid, cutting oils, and as a solvent for adhesives, insecticides, and lacquers; [NTP] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Metal Machining [Category: Heat or Machine]; Painting (Solvents) [Category: Paint]; Working with Glues and Adhesives [Category: Other]; Farming (Pesticides) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for GAMMA-VALEROLACTONE
INCI name
GAMMA-VALEROLACTONE
Description
Dihydro-5-methyl-2(3H)-furanone; gamma-Valerolactone
Record provenance
- Inventory reference
- 41281
- Imported identity
- GAMMA-VALEROLACTONE
- Source update
- 02/03/2011
Annex records for GAMMA-VALEROLACTONE
Key data
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How GAMMA-VALEROLACTONE appears in the CosIng inventory
The CosIng inventory lists GAMMA-VALEROLACTONE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
GAMMA-VALEROLACTONE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for GAMMA-VALEROLACTONE
This page reproduces the CosIng inventory entry for GAMMA-VALEROLACTONE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.
Use this inventory page to research GAMMA-VALEROLACTONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
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