METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL
2,2'-Methylene-bis-(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol)
METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL is linked to 2 EU annex records on this page. Inventory note: VI/23.
Regulatory evidence by market
This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.
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| Market | Evidence status | Records | Source language |
|---|---|---|---|
| European Union | Evidence linked Positive-list entry with conditions Open this evidence | 2 | English and EU languages |
| Great Britain | Evidence linked Permitted list with conditions Open this evidence | 2 | English |
| Canada | Source mapped Official source mapped; ingredient rule not imported | 0 | English and French |
| New Zealand | Evidence linked Permitted list with conditions Open this evidence | 2 | English |
| ASEAN | Evidence linked Permitted list with conditions Open this evidence | 2 | English and national languages |
| China | Source mapped Official source mapped; ingredient rule not imported | 0 | Chinese with selected English material |
| Japan | Source mapped Official source mapped; ingredient rule not imported | 0 | Japanese; official English translation available |
| South Korea | Evidence linked Restricted Open this evidence | 1 | Korean with some English names |
| United States | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Australia | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Brazil | Source mapped Official source mapped; ingredient rule not imported | 0 | Portuguese with INCI crosswalks |
| India | Source mapped Official source mapped; ingredient rule not imported | 0 | English and Hindi |
| Saudi Arabia | Source mapped Official source mapped; ingredient rule not imported | 0 | Arabic and English |
Chemical identity and properties
- IUPAC name
- 2-(benzotriazol-2-yl)-6-[[3-(benzotriazol-2-yl)-2-hydroxy-5-(2,4,4-trimethylpentan-2-yl)phenyl]methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol
- Molecular formula
- C41H50N6O2
- Molecular weight
- 658.9 g/mol
- Exact mass
- 658.39952486 Da
- XLogP3
- 12.8
- Topological polar surface area
- 102.0 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 6
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:135865
- ChEMBL:CHEMBL2104957
- EPA DTXSID:DTXSID2046703
- PubMed:23320122
- PubMed:21504696
- PubMed:20038348
Evidence from additional scientific databases
EMBL-EBI ChEBI
bisoctrizole
- Formula
- C41H50N6O2
- Average mass
- 658.891 g/mol
- Monoisotopic mass
- 658.39952 Da
- Formal charge
- 0
- diarylmethane — is a (CHEBI:51614)
- diarylmethane — is a (CHEBI:51614)
Additional curated names
Cross-references from this source
- CAS: 103597-45-1 — DrugCentral
- MANUAL_X_REF: 3031 — DrugCentral
Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2017-02-23. Retrieved: 2026-08-31. Open source record
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- LogP: 12.7 Source: DrugBank
- Melting Point: 195 Source: DrugBank
- Physical Description: Other Solid; Dry Powder; Large Crystals Source: EPA Chemical Data Reporting (CDR)
- Solubility: < 5 ng/L at 25 °C Source: DrugBank
- GHS Hazard Statements: H413: May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Precautionary Statement Codes: P273, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Note: This chemical does not meet GHS hazard criteria for 1.7% (14 of 842) of reports. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H413 (98.3%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P273, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 842 reports by companies from 4 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 14 of 842 reports by companies.; There are 3 notifications provided by 828 of 842 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H413 (100%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 107 reports by companies from 1 notifications to the ECHA C&L Inventory.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H413: May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
- Precautionary Statement Codes: P273, and P501 (click each P-code to see the statement) Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
- Consumer Uses: UV stabilizer; Other Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Stabilizing agent; Other; UV stabilizer Source: EPA Chemical Data Reporting (CDR)
- Uses: Plastics -> Typical concentration range in plastic materials -> 0.2 - 6.0% Source: NORMAN Suspect List Exchange
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| EMBL-EBI ChEBI | Exact match | 2026-08-31 |
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL
INCI name
METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL
INN name
bisoctrizole
Description
2,2'-Methylene-bis-(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol)
Record provenance
- Inventory reference
- 38987
- Imported identity
- METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL
- Source update
- 06/08/2020
Annex records for METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL
METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL
METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL (NANO)
Key data
- LIGHT STABILIZER
- Protecting the cosmetic product from deterioration effects of light.
- UV FILTER
- Exclusively or mainly intended to protect the skin and/or hair against certain UV radiation by absorbing, reflecting or scattering UV radiation. All authorised UV filters are substances in the positive list of Annex VI to the Cosmetics Regulation 1223/2009.
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
The 5 markets that hold a rule for this substance do not classify it the same way.
- restricted
- South Korea
- permitted on a positive list
- European UnionGreat BritainNew ZealandASEAN
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL appears in the CosIng inventory
The CosIng inventory lists METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL as a cosmetic ingredient and this page links it to 2 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL
This page combines the CosIng inventory entry for METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL with 2 linked Annex II–VI records from the local dataset built from public European Commission cosmetic ingredient materials.
Use this inventory page to research METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
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