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InventoryRef 3877530/07/2020

TRISODIUM NTA

Trisodium nitrilotriacetate

TRISODIUM NTA is linked to 1 EU annex record on this page. Inventory note: II/1490.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Prohibited entry found
Open this evidence		1English and EU languages
Great BritainEvidence linked
Prohibited
Open this evidence		1English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandEvidence linked
Prohibited
Open this evidence		1English
ASEANEvidence linked
Prohibited
Open this evidence		1English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaEvidence linked
Prohibited
Open this evidence		1English and Hindi
Saudi ArabiaEvidence linked
Prohibited
Open this evidence		1Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 5064-31-3
CAS 5064-31-3PubChem CID 21152

Trisodium Nitrilotriacetate

Sodium nitrilotriacetate is an organic sodium salt composed of sodium and nitrilotriacetate ions in a 3:1 ratio. It has a role as a carcinogenic agent and a nephrotoxic agent. It contains a nitrilotriacetate(3-). — ChEBI

IUPAC name
trisodium;2-[bis(carboxylatomethyl)amino]acetate
Molecular formula
C6H6NNa3O6
Molecular weight
257.08 g/mol
Exact mass
256.98881976 Da
Topological polar surface area
124.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
7
Covalent units
4
Defined stereocentres
0

Also known as

Nitrilotriacetic acid trisodium saltTrisodium NTAHampshire NTANtana3Sodium nitrilotriacetateNTA Trisodium saltSyntron ATrisodium aminotriacetate
16 more reported names
Masquol np 140Versene NTA 150Versene NTA 335Hampshire NTA 150Chemcolox 365 powderNitrilotriacetic acid, trisodium saltTrisodium 2,2',2''-nitrilotriacetateTrisodium nitrilotriacetic acidNitrilotriacetate trisodium saltTrisodium N,N-bis(carboxymethyl)glycinateE3C8R2M0XDGlycine, N,N-bis(carboxymethyl)-, trisodium saltAcetic acid, nitrilotri-, trisodium saltN,N-Bis(carboxymethyl)glycine, trisodium saltCHEBI:132766RefChem:192175
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for TRISODIUM NTA

INCI name

TRISODIUM NTA

Description

Trisodium nitrilotriacetate

Record provenance

Inventory reference
38775
Imported identity
TRISODIUM NTA
Source update
30/07/2020
European Commission CosIng source notes

Key data

CAS
5064-31-3
EC
225-768-6
Restriction
II/1490
Function
CHELATING
Forming complexes with metal ions which could affect the stability and/or appearance of cosmetics.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#29475 · TRISODIUM NTA

Ingredients with overlapping formulation functions

TRISODIUM EDTACHELATING
TRISODIUM ETHYLENEDIAMINE DISUCCINATECHELATING
TRISODIUM FRUCTOSE DIPHOSPHATEANTIOXIDANT, CHELATING
TRISODIUM HEDTACHELATING
TRISODIUM PHOSPHATEBUFFERING, CHELATING
TRISODIUM SULFOSUCCINATEBUFFERING, CHELATING, SURFACTANT - CLEANSING, SURFACTANT - HYDROTROPE
VANILLYLIDENE PENTANEDIONEANTIOXIDANT, CHELATING, SKIN PROTECTING
VERBASCOSIDEANTIOXIDANT, BLEACHING, CHELATING, SKIN PROTECTING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How TRISODIUM NTA appears in the CosIng inventory

The CosIng inventory lists TRISODIUM NTA as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TRISODIUM NTA is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TRISODIUM NTA appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for TRISODIUM NTA reads: "II/1490". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, TRISODIUM NTA carries the following function designation(s):

CAS 5064-31-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for TRISODIUM NTA

This page combines the CosIng inventory entry for TRISODIUM NTA with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research TRISODIUM NTA and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

View sourcesView updates

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