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InventoryRef 3810315/10/2010

SODIUM THIOSULFATE

Sodium thiosulphate

SODIUM THIOSULFATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 10102-17-7
CAS 10102-17-7PubChem CID 61475

Sodium Thiosulfate Pentahydrate

Sodium thiosulfate pentahydrate is a hydrate consisting of sodium thiosulfate with 5 mol eq. of water. It has a role as a nephroprotective agent, an antifungal drug and an antidote to cyanide poisoning. It contains a sodium thiosulfate. — ChEBI

IUPAC name
disodium;dioxido-oxo-sulfanylidene-lambda6-sulfane;pentahydrate
Molecular formula
H10Na2O8S2
Molecular weight
248.19 g/mol
Exact mass
247.96124818 Da
Topological polar surface area
109.0 Ų
Hydrogen-bond donors
5
Hydrogen-bond acceptors
9
Covalent units
8
Defined stereocentres
0

Also known as

Disodium thiosulfate pentahydrateSodium thiosulfate, pentahydrateThiosulfuric acid (H2S2O3), disodium salt, pentahydrateCHEBI:32150AntichlorRefChem:931939pentahydrate of sodium thiosulfate600-156-5
16 more reported names
sodium thiosulphate pentahydrateNa2S2O3.5H2OSodium thiosulfate (pentahydrate)Thiosulfuric acid (H2S2O3), sodium salt, hydrate (1:2:5)TinverSodium Hyposulfite PentahydrateCCRIS 3952UNII-HX1032V43MSodium thiosulfate [USP:JAN]Pedmarqsi (TN)Sulfactol (TN)Detoxol (TN)Pedmark (TN)Sodium thiosulfate (USP)H10Na2O8S2sodium thiosulfate-pentahydrate
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:32150

sodium thiosulfate pentahydrate

A hydrate consisting of sodium thiosulfate with 5 mol eq. of water.

Formula
5H2O.2Na.O3S2
Average mass
248.186 g/mol
Monoisotopic mass
247.96125 Da
Formal charge
0
  • hydrate — is a (CHEBI:35505)
  • antidote to cyanide poisoning — has role (CHEBI:90749)
  • nephroprotective agent — has role (CHEBI:76595)
  • antifungal drug — has role (CHEBI:86327)
  • sodium thiosulfate — has part (CHEBI:132112)
  • antidote to cyanide poisoning — has role (CHEBI:90749)
  • nephroprotective agent — has role (CHEBI:76595)
  • antifungal drug — has role (CHEBI:86327)
  • hydrate — is a (CHEBI:35505)
Additional curated names
sodium sulfurothioate--water (1/5)disodium thiosulfate pentahydratedisodium thiosulphate pentahydrateNa2S2O3.5H2Osodium sulfurothioate hydrate (2:1:5)Sodium thiosulfatesodium thiosulfate pentahydratethiosulfuric acid, disodium salt, pentahydrate
Cross-references from this source

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2024-05-17. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match61475

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 98.6% (277 of 281) of all reports. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 277 of 281 companies (only 1.4% companies provided GHS information). For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 281 reports by companies from 6 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 277 of 281 reports by companies.; There are 4 notifications provided by 4 of 281 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Industry Uses: Laboratory chemicals; Reducing agent; Not Known or Reasonably Ascertainable; Cleaning agent; Dehydrating agent (desiccant); Processing aids not otherwise specified; Tanning agents not otherwise specified Source: EPA Chemical Data Reporting (CDR)
  • Sources/Uses: Used to remove chlorine from solutions; to bleach paper, bone, straw, and ivory; as a fixer in photography; to extract silver from ores; as mordant in dyeing and printing textiles; in leather manufacturing; in pharmaceutical production (antioxidant), and as an antidote for cyanide poisoning; [Merck Index] Permitted for use as an inert ingredient in non-food pesticide products; [EPA] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Pulp and Paper Processing [Category: Industry]; Leather Tanning and Processing [Category: Industry]; Photographic Processing [Category: Other]; Textiles (Printing, Dyeing, or Finishing) [Category: Industry]; Metal Extraction and Refining [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 7772-98-7
CAS 7772-98-7PubChem CID 24477

Sodium Thiosulfate

Sodium thiosulfate is an inorganic sodium salt composed of sodium and thiosulfate ions in a 2:1 ratio. It has a role as a nephroprotective agent, an antifungal drug and an antidote to cyanide poisoning. It contains a thiosulfate(2-). — ChEBI

IUPAC name
disodium;dioxido-oxo-sulfanylidene-lambda6-sulfane
Molecular formula
Na2O3S2
Molecular weight
158.11 g/mol
Exact mass
157.90842477 Da
Topological polar surface area
104.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
3
Defined stereocentres
0

Also known as

Sodium thiosulphateDisodium thiosulfateSodothiolHypoChlorine ControlChlorine CureSodium thiosulfate, anhydrousThiosulfuric acid, disodium salt
16 more reported names
Sodium thiosulfate (Na2S2O3)Sodium thiosulphate (Na2S2O3)Sodium oxide sulfide (Na2S2O3)L0IYT1O31NThiosulfuric acid (H2S2O3), disodium saltIns no.539Ins-539Sodium thiosulphate, anhydrousCHEBI:132112E-539sulfothiorineRefChem:6498Cyanide Antidote PackageThiosulfate, Sodium, PentahydrateSodium Nitrite and Sodium Thiosulfate231-867-5
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for SODIUM THIOSULFATE

INCI name

SODIUM THIOSULFATE

INN name

sodium thiosulfate

Ph. Eur. name

natrii thiosulfas

Description

Sodium thiosulphate

Record provenance

Inventory reference
38103
Imported identity
SODIUM THIOSULFATE
Source update
15/10/2010
European Commission CosIng source notes
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Key data

CAS
7772-98-7 / 10102-17-7
EC
231-867-5 / -
Restriction
—
Function
REDUCING
Changing the chemical nature of another ingredient by adding hydrogen (or removing oxygen).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#27066 · SODIUM THIOSULFATE

Ingredients with overlapping formulation functions

SODIUM METABISULFITEANTIOXIDANT, PRESERVATIVE, REDUCING
SODIUM OXYMETHYLENE SULFOXYLATEREDUCING
SODIUM SULFITEANTIOXIDANT, HAIR WAVING OR STRAIGHTENING, PRESERVATIVE, REDUCING
SODIUM THIOGLYCOLATEANTIOXIDANT, DEPILATORY, HAIR WAVING OR STRAIGHTENING, REDUCING
SODIUM TOCOPHERYL PHOSPHATEANTIOXIDANT, EMULSION STABILISING, REDUCING, SKIN CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT …
SR-(METHIONYL R-GREEN MUSSEL OLIGOPEPTIDE-1)ANTIOXIDANT; HAIR CONDITIONING; HUMECTANT; REDUCING; SKIN CONDITIONING - HUMECTANT
SR-(METHIONYL R-MUSSEL POLYPEPTIDE-1 R-MUSSEL OLIGOPEPTIDE-1 R-MUSSEL POLYPEPTI…ANTIOXIDANT; HAIR CONDITIONING; HUMECTANT; REDUCING; SKIN CONDITIONING - HUMECTANT
SR-(METHIONYL S-GREEN MUSSEL POLYPEPTIDE-1 OLIGOPEPTIDE-247)ANTIOXIDANT; HAIR CONDITIONING; HUMECTANT; REDUCING; SKIN CONDITIONING - HUMECTANT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How SODIUM THIOSULFATE appears in the CosIng inventory

The CosIng inventory lists SODIUM THIOSULFATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

SODIUM THIOSULFATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

SODIUM THIOSULFATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, SODIUM THIOSULFATE carries the following function designation(s):

CAS 7772-98-7 / 10102-17-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for SODIUM THIOSULFATE

This page reproduces the CosIng inventory entry for SODIUM THIOSULFATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research SODIUM THIOSULFATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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