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CAS 54-47-7 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 3738115/10/2010

PYRIDOXAL 5-PHOSPHATE

Pyridoxal 5'-(dihydrogen phosphate).

PYRIDOXAL 5-PHOSPHATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 54-47-7

CAS 54-47-7PubChem CID 1051

Pyridoxal 5'-phosphate

Pyridoxal 5'-phosphate is the monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal. It has a role as an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor, a coenzyme, a cofactor, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is a member of methylpyridines, a vitamin B6 phosphate, a monohydroxypyridine and a pyridinecarbaldehyde. It is functionally related to a pyridoxal. It is a conjugate acid of a pyridoxal 5'-phosphate(2-). — ChEBI

IUPAC name: (4-formyl-5-hydroxy-6-methyl-3-pyridinyl)methyl dihydrogen phosphate

Molecular formula: C8H10NO6P
Molecular weight: 247.14 g/mol
Exact mass: 247.02457404 Da
XLogP3: -1.1
Topological polar surface area: 117.0 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 7
Covalent units: 1
Defined stereocentres: 0

Also known as

pyridoxal phosphateCodecarboxylasepyridoxal 5-phosphatePyromijinVitazechs(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphatePyridoxyl phosphatePyridoxal P

16 more reported names

PidopidonBiosechsHairoxalHimitanPyridoxal-5'-phosphateHiadelonPydoxalPhosphopyridoxalSechvitanPiodelApolon B6pyridoxal-PVitahexin PHexermin PPhosphopyridoxal coenzymeCoenzyme B6

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:18405
ChEMBL:CHEMBL82202
EPA DTXSID:DTXSID4048351
PubMed:35151785
PubMed:27387750
PubMed:23105849
PubMed:23027742
PubMed:22973101
PubMed:22932684
PubMed:22900314
PubMed:22878384
PubMed:22857864
PubMed:22845654
PubMed:22822451
PubMed:22803330

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for PYRIDOXAL 5-PHOSPHATE

INCI name

PYRIDOXAL 5-PHOSPHATE

Description

Pyridoxal 5'-(dihydrogen phosphate).

Record provenance

Inventory reference: 37381
Imported identity: PYRIDOXAL 5-PHOSPHATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for PYRIDOXAL 5-PHOSPHATE

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Key data

CAS

54-47-7

200-208-3

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#23736 · PYRIDOXAL 5-PHOSPHATE

Ingredients with overlapping formulation functions

PYRACANTHA FORTUNEANA FRUIT EXTRACTSKIN CONDITIONING

PYRENARIA BUISANENSIS LEAF EXTRACTHUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

PYRICARBATECHELATING, SKIN CONDITIONING

PYRIDINEDICARBOXYLIC ACIDSKIN CONDITIONING

PYRIDOXINEANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

PYRIDOXINE CYCLIC PHOSPHATEHAIR CONDITIONING, SKIN CONDITIONING

PYRIDOXINE DICAPRYLATEANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

PYRIDOXINE DILAURATEANTISTATIC, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How PYRIDOXAL 5-PHOSPHATE appears in the CosIng inventory

The CosIng inventory lists PYRIDOXAL 5-PHOSPHATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

PYRIDOXAL 5-PHOSPHATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

PYRIDOXAL 5-PHOSPHATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, PYRIDOXAL 5-PHOSPHATE carries the following function designation(s):

SKIN CONDITIONING

CAS 54-47-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for PYRIDOXAL 5-PHOSPHATE

This page reproduces the CosIng inventory entry for PYRIDOXAL 5-PHOSPHATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research PYRIDOXAL 5-PHOSPHATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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