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InventoryRef 7913915/10/2010

PYRIDOXINE

3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-; vitamine B6

PYRIDOXINE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 65-23-6
CAS 65-23-6PubChem CID 1054

Pyridoxine

Pyridoxine is a hydroxymethylpyridine with hydroxymethyl groups at positions 4 and 5, a hydroxy group at position 3 and a methyl group at position 2. The 4-methanol form of vitamin B6, it is converted intoto pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid. It has a role as a cofactor, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is a member of methylpyridines, a vitamin B6, a monohydroxypyridine and a hydroxymethylpyridine. ChEBI

IUPAC name
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol
Molecular formula
C8H11NO3
Molecular weight
169.18 g/mol
Exact mass
169.07389321 Da
XLogP3
-0.8
Topological polar surface area
73.6 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

PyridoxolPyridoxin3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridineAdermineGravidoxHydoxinPyridoxolum3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-
16 more reported names
5-Hydroxy-6-methyl-3,4-pyridinedimethanolPiridoxinaPyridoxinumPiridossina3-Hydroxy-4,5-dimethylol-alpha-picolineHexabione2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine2-Methyl-3-hydroxy-4,5-di(hydroxymethyl)pyridineVitamin V62-Methyl-4,5-bis(hydroxymethyl)-3-hydroxypyridineCHEBI:16709KV2JZ1BI6Z2-methyl-3-hydroxy-4,5-dihydroxymethylpyridineNSC-7591482-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin3-hydroxy-2-Picoline-4,5-dimethanol
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 8059-24-3
CAS 8059-24-3PubChem CID 104817

Vitamin B6

Vitamin B6 is a group of water-soluble vitamins essential for metabolism and normal physiological functions. B6 vitamins, including pyridoxine, pyridoxal, and pyridoxamine, are converted in vivo to pyridoxal phosphate, a cofactor necessary for the synthesis of amino acids, neurotransmitters, and sphingolipids. More than 100 enzymes involved in protein metabolism require vitamin B6 as a cofactor. Vitamin B6 is essential to red blood cell, nervous system, and immune systems functions and helps maintain normal blood glucose levels. Vitamin B6 is found in a wide variety of foods including cereals, beans, meat, poultry, fish, and some fruits and vegetables. (NCI04) NCI Thesaurus (NCIt)

IUPAC name
(5-hydroxy-4,6-dimethyl-3-pyridinyl)methyl phosphate
Molecular formula
C8H10NO5P-2
Molecular weight
231.14 g/mol
Exact mass
231.02965942 Da
XLogP3
-0.9
Topological polar surface area
106.0 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
0

Also known as

Vitamin B 6RefChem:902002VIT B6CHEBI:27306232-503-8Vitamin B-6(5-hydroxy-4,6-dimethylpyridin-3-yl)methyl phosphateEINECS 232-503-8
1 more reported name
BIOTIN, IMMOBILIZED ON DEXTRAN-LYSINE
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for PYRIDOXINE

INCI name

PYRIDOXINE

INN name

pyridoxine

Description

3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-; vitamine B6

Record provenance

Inventory reference
79139
Imported identity
PYRIDOXINE
Source update
15/10/2010
European Commission CosIng source notes

Key data

CAS
65-23-6 / 8059-24-3
EC
200-603-0 / 232-503-8
Restriction
Function
ANTISTATIC
Preventing and/or reducing static electricity by neutralising electrical charge on surfaces.
HAIR CONDITIONING
Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How PYRIDOXINE appears in the CosIng inventory

The CosIng inventory lists PYRIDOXINE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

PYRIDOXINE is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

PYRIDOXINE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, PYRIDOXINE carries the following function designation(s):

CAS 65-23-6 / 8059-24-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for PYRIDOXINE

This page reproduces the CosIng inventory entry for PYRIDOXINE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research PYRIDOXINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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