What does the restriction note for P-PHENYLENEDIAMINE HCL mean?

The restriction field for P-PHENYLENEDIAMINE HCL reads: III/8a. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 624-18-0?

CAS 624-18-0 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains P-PHENYLENEDIAMINE HCL?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3725015/10/2010

P-PHENYLENEDIAMINE HCL

Benzene-1,4-diamine dihydrochloride (CI 76060)

P-PHENYLENEDIAMINE HCL is linked to 2 EU annex records on this page. Inventory note: III/8a.

INCI Checker Compare all markets Search similar

Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

Compare markets

Swipe or scroll horizontally to see every column.

Market	Evidence status	Records	Source language
European Union	Evidence linked Restricted entry found Open this evidence	2	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Restricted Open this evidence	2	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Evidence linked Prohibited + Restricted Open this evidence	2	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 624-18-0

CAS 624-18-0PubChem CID 12205

1,4-Diaminobenzene dihydrochloride

1,4-phenylenediamine dihydrochloride appears as white to slightly reddish crystals or gray powder. (NTP, 1992) — CAMEO Chemicals

IUPAC name: benzene-1,4-diamine;dihydrochloride

Molecular formula: C6H10Cl2N2
Molecular weight: 181.06 g/mol
Exact mass: 180.0221037 Da
Topological polar surface area: 52.0 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 2
Covalent units: 3
Defined stereocentres: 0

Also known as

p-Phenylenediamine dihydrochloride1,4-Phenylenediamine dihydrochloridebenzene-1,4-diamine dihydrochlorideFourrine DSPelagol Grey CDDurafur Black RCFourrine 641,4-Benzenediamine dihydrochloride

16 more reported names

p-PD HClp-Phenylenediamine HClPelagol CD1,4-Benzenediamine, dihydrochloridep-Pda HClOxidation Base 10AC.I. Oxidation Base 10A4-Aminoaniline dihydrochloridep-Benzenediamine dihydrochloridep-Diaminobenzene dihydrochlorideCI Oxidation Base 10ANCI-C03930p-Phenylenediamine, dihydrochloridep-Aminoaniline dihydrochlorideCCRIS 510Phenylenediamine dihydrochloride

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL3561416
EPA DTXSID:DTXSID8021141

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for P-PHENYLENEDIAMINE HCL

INCI name

P-PHENYLENEDIAMINE HCL

Description

Benzene-1,4-diamine dihydrochloride (CI 76060)

Record provenance

Inventory reference: 37250
Imported identity: P-PHENYLENEDIAMINE HCL
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for P-PHENYLENEDIAMINE HCL

Annex III Restriction reference

Entry 8a

p-Phenylenediamine and its salts

CAS: 106-50-3 / 624-18-0 / 16245-77-5

EC: 203-404-7 / 210-834-9 / 240-357-1

Annex III Identified ingredient

Entry 8b

p-Phenylenediamine; p-Phenylenediamine HCl; p-Phenylenediamine Sulphate

CAS: 106-50-3 / 624-18-0 / 16245-77-5

EC: 203-404-7 / 210-834-9 / 240-357-1

Key data

CAS

624-18-0

210-834-9

Restriction

III/8a

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#23228 · P-PHENYLENEDIAMINE HCl

The markets do not agree about this substance: it is prohibited in some and permitted under conditions in others, across the 3 markets that hold a rule for it.

prohibited: South Korea
restricted: European Union New Zealand

South Korea holds more than one rule for this substance, so its position there depends on the use.

See every substance the markets disagree about

Ingredients with overlapping formulation functions

P-METHYLAMINOPHENOL SULFATEHAIR DYEING

P-PHENETIDINEHAIR DYEING

P-PHENYLENEDIAMINEHAIR DYEING

P-PHENYLENEDIAMINE GLYCIDYL ETHERHAIR DYEING

P-PHENYLENEDIAMINE HYDROXYETHYL ETHERHAIR DYEING

P-PHENYLENEDIAMINE SULFATEHAIR DYEING

PEG-3 2,2'-DI-P-PHENYLENEDIAMINEHAIR DYEING

PEG-3,2',2'-DI-P-PHENYLENEDIAMINEHAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How P-PHENYLENEDIAMINE HCL appears in the CosIng inventory

The CosIng inventory lists P-PHENYLENEDIAMINE HCL as a cosmetic ingredient and this page links it to 2 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

P-PHENYLENEDIAMINE HCL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

P-PHENYLENEDIAMINE HCL appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for P-PHENYLENEDIAMINE HCL reads: "III/8a". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, P-PHENYLENEDIAMINE HCL carries the following function designation(s):

HAIR DYEING

CAS 624-18-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

View CAS records

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Open INCI Checker

Source note for P-PHENYLENEDIAMINE HCL

This page combines the CosIng inventory entry for P-PHENYLENEDIAMINE HCL with 2 linked Annex II–VI records from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research P-PHENYLENEDIAMINE HCL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

View sources View updates

Tools & next steps

Check your formula

Scan a full INCI list to detect P-PHENYLENEDIAMINE HCL and any linked EU annex restrictions or allergen flags.

INCI Checker

Search similar ingredients

Find other inventory ingredients and annex entries related to P-PHENYLENEDIAMINE HCL, its identifiers or nearby name variants.