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CAS 6485-39-8 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 3515715/10/2010

MANGANESE GLUCONATE

Bis(D-gluconato-O1,O2)manganese

MANGANESE GLUCONATE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 6485-39-8

CAS 6485-39-8PubChem CID 22988

Manganese gluconate

Manganese gluconate is a manganese salt of gluconic acid with the chemical formula C12H22MnO14 x 2H2O. It is typically obtained by reacting manganese carbonate with gluconic acid in aqueous medium and then crystallizing the product to form a slightly pink powder. Manganese gluconate is a direct ingredient in food substances as a nutrient supplement. In pharmaceutical preparations it is used as a [DB06757] supplement. — DrugBank

IUPAC name: manganese(2+);bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate)

Molecular formula: C12H22MnO14
Molecular weight: 445.23 g/mol
Exact mass: 445.038998 Da
Topological polar surface area: 283.0 Å²
Hydrogen-bond donors: 10
Hydrogen-bond acceptors: 14
Covalent units: 3
Defined stereocentres: 8

Also known as

Manganese D-gluconateManganese(II) gluconateGluconic acid, manganese salt (2:1)Manganese, bis(D-gluconato-O1,O2)-, (T-4)-7G09WJ8QIRManganese gluconate anhydrousNSC-132049RefChem:155581

16 more reported names

9YY2F980SVMANGANESE GLUCONATE, UNSPECIFIEDManganese, bis(D-gluconato-kappaO1,kappaO2)-, (T-4)-Manganese D-gluconate (1:2)D-Gluconic acid, manganese salt (2:1)Manganese gluconate [USP]manganese(2+);(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoateManganese, bis(D-gluconato-kO1,kO2)-, (T-4)-C12H22MnO14CCRIS 3942HSDB 1225Bis(D-gluconato-O1,O2)manganeseEINECS 229-350-4UNII-7G09WJ8QIRManganese(2+) dihexonateBis(D-gluconato-O(sup 1),O(sup 2)) manganese

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID30983438

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for MANGANESE GLUCONATE

INCI name

MANGANESE GLUCONATE

Description

Bis(D-gluconato-O1,O2)manganese

Record provenance

Inventory reference: 35157
Imported identity: MANGANESE GLUCONATE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for MANGANESE GLUCONATE

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Key data

CAS

6485-39-8

229-350-4

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#15971 · MANGANESE GLUCONATE

Ingredients with overlapping formulation functions

MANGANESE ASPARTATESKIN CONDITIONING

MANGANESE CHLORIDESKIN CONDITIONING

MANGANESE CITRATESKIN CONDITIONING

MANGANESE FRUCTOSE DIPHOSPHATEANTIOXIDANT, SKIN CONDITIONING

MANGANESE GLYCINATEANTIOXIDANT, SKIN CONDITIONING

MANGANESE PCAHUMECTANT, MOISTURISING, SKIN CONDITIONING

MANGANESE PYRIDOXAL 5-PHOSPHATEANTIOXIDANT, SKIN CONDITIONING

MANGANESE SULFATESKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How MANGANESE GLUCONATE appears in the CosIng inventory

The CosIng inventory lists MANGANESE GLUCONATE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

MANGANESE GLUCONATE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

MANGANESE GLUCONATE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, MANGANESE GLUCONATE carries the following function designation(s):

SKIN CONDITIONING

CAS 6485-39-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for MANGANESE GLUCONATE

This page reproduces the CosIng inventory entry for MANGANESE GLUCONATE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research MANGANESE GLUCONATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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