HOMOSALATE
Benzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl ester
HOMOSALATE is linked to 1 EU annex record on this page. Inventory note: VI/3.
Regulatory evidence by market
This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.
Swipe or scroll horizontally to see every column.
| Market | Evidence status | Records | Source language |
|---|---|---|---|
| European Union | Evidence linked Positive-list entry with conditions Open this evidence | 1 | English and EU languages |
| Great Britain | Evidence linked Permitted list with conditions Open this evidence | 1 | English |
| Canada | Source mapped Official source mapped; ingredient rule not imported | 0 | English and French |
| New Zealand | Evidence linked Permitted list with conditions Open this evidence | 1 | English |
| ASEAN | Evidence linked Permitted list with conditions Open this evidence | 1 | English and national languages |
| China | Source mapped Official source mapped; ingredient rule not imported | 0 | Chinese with selected English material |
| Japan | Source mapped Official source mapped; ingredient rule not imported | 0 | Japanese; official English translation available |
| South Korea | Evidence linked Restricted Open this evidence | 1 | Korean with some English names |
| United States | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Australia | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Brazil | Source mapped Official source mapped; ingredient rule not imported | 0 | Portuguese with INCI crosswalks |
| India | Source mapped Official source mapped; ingredient rule not imported | 0 | English and Hindi |
| Saudi Arabia | Source mapped Official source mapped; ingredient rule not imported | 0 | Arabic and English |
Chemical identity and properties
Homosalate
2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester is a member of phenols and a benzoate ester. It is functionally related to a salicylic acid. — ChEBI
- IUPAC name
- (3,3,5-trimethylcyclohexyl) 2-hydroxybenzoate
- Molecular formula
- C16H22O3
- Molecular weight
- 262.34 g/mol
- Exact mass
- 262.15689456 Da
- XLogP3
- 5.0
- Topological polar surface area
- 46.5 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 3
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:91642
- ChEMBL:CHEMBL1377575
- EPA DTXSID:DTXSID1026241
- PubMed:39159849
- PubMed:38381479
- PubMed:28551711
- PubMed:24004914
- PubMed:23769903
- PubMed:23062433
- PubMed:22884209
- PubMed:22749456
- PubMed:22669305
- PubMed:22612478
- PubMed:22214440
- PubMed:21872075
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Boiling Point: 322 to 329 °F at 760 mmHg (NTP, 1992) Source: CAMEO Chemicals
- Density: 1.045 at 77 °F (NTP, 1992) - Denser than water; will sink Source: CAMEO Chemicals
- Flash Point: greater than 200 °F (NTP, 1992) Source: CAMEO Chemicals
- Physical Description: 3,3,5-trimethylcyclohexylsalicylate appears as viscous or light yellow to slightly tan liquid or oil. (NTP, 1992) Source: CAMEO Chemicals
- Solubility: Insoluble (<1 mg/ml at 79 °F) (NTP, 1992) Source: CAMEO Chemicals
- First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
- Note: This chemical does not meet GHS hazard criteria for 67% (152 of 227) of all reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H315 (16.7%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (16.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (16.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H361d (11.5%): Suspected of damaging the unborn child [Warning Reproductive toxicity]; H410 (11.5%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P203, P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 227 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 152 of 227 reports by companies.; There are 3 notifications provided by 75 of 227 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Industry Uses: Not Known or Reasonably Ascertainable Source: EPA Chemical Data Reporting (CDR)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for HOMOSALATE
INCI name
HOMOSALATE
INN name
homosalate
Description
Benzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl ester
Record provenance
- Inventory reference
- 34299
- Imported identity
- HOMOSALATE
- Source update
- 06/08/2020
Annex records for HOMOSALATE
Key data
- FRAGRANCE
- Imparting an odour or taste. Creating a perceivable pleasant smell and/or masking a bad smell.
- UV ABSORBER
- Protecting the cosmetic product from the effects of UV-light.
- UV FILTER
- Exclusively or mainly intended to protect the skin and/or hair against certain UV radiation by absorbing, reflecting or scattering UV radiation. All authorised UV filters are substances in the positive list of Annex VI to the Cosmetics Regulation 1223/2009.
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
The 5 markets that hold a rule for this substance do not classify it the same way.
- restricted
- South Korea
- permitted on a positive list
- European UnionGreat BritainNew ZealandASEAN
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How HOMOSALATE appears in the CosIng inventory
The CosIng inventory lists HOMOSALATE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.
HOMOSALATE is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for HOMOSALATE
This page combines the CosIng inventory entry for HOMOSALATE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.
Use this inventory page to research HOMOSALATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
Tools & next steps
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