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InventoryRef 3415803/09/2014

GLYOXYLIC ACID

Glyoxylic acid

GLYOXYLIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 298-12-4
CAS 298-12-4PubChem CID 760

Glyoxylic Acid

Glyoxylic acid is a 2-oxo monocarboxylic acid that is acetic acid bearing an oxo group at the alpha carbon atom. It has a role as a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is an aldehydic acid and a 2-oxo monocarboxylic acid. It is a conjugate acid of a glyoxylate. ChEBI

IUPAC name
oxaldehydic acid
Molecular formula
C2H2O3
Molecular weight
74.04 g/mol
Exact mass
74.000393922 Da
XLogP3
-0.3
Topological polar surface area
54.4 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

2-Oxoacetic AcidGlyoxalic acidOxoacetic acidOxoethanoic acidFormylformic acidAcetic acid, oxo-Oxalaldehydic acidglyoxylate
16 more reported names
alpha-Ketoacetic acidFormic acid, formyl-glyoxalateKyselina glyoxylovaJQ39C92HH6NSC-27785CHEBI:16891CHEBI:36655RefChem:663965206-058-5Acetic acid, 2-oxo-CCRIS 1455HSDB 5559563-96-2NSC 27785C2H2O3
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for GLYOXYLIC ACID

INCI name

GLYOXYLIC ACID

Description

Glyoxylic acid

Record provenance

Inventory reference
34158
Imported identity
GLYOXYLIC ACID
Source update
03/09/2014
European Commission CosIng source notes

Key data

Restriction
Function
ANTISTATIC
Preventing and/or reducing static electricity by neutralising electrical charge on surfaces.
BUFFERING
Stabilising the pH of an aqueous medium in a narrow range even if an acid or base is added. Altering and/or maintaining a cosmetic product's pH at the desired level.
HAIR WAVING OR STRAIGHTENING
Modifying the chemical structure of the hair, allowing it to be set in the style required (permanent waves or hair straightening).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How GLYOXYLIC ACID appears in the CosIng inventory

The CosIng inventory lists GLYOXYLIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

GLYOXYLIC ACID is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

GLYOXYLIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, GLYOXYLIC ACID carries the following function designation(s):

CAS 298-12-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for GLYOXYLIC ACID

This page reproduces the CosIng inventory entry for GLYOXYLIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research GLYOXYLIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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