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InventoryRef 3265810/08/2020

CHLORHEXIDINE DIACETATE

N,N'-bis(4-Chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine di(acetate)

CHLORHEXIDINE DIACETATE is linked to 1 EU annex record on this page. Inventory note: V/42.

Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Positive-list entry with conditions
Open this evidence
1English and EU languages
Great BritainSource mapped
Official source mapped; ingredient rule not imported
0English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandEvidence linked
Permitted list with conditions
Open this evidence
1English
ASEANSource mapped
Official source mapped; ingredient rule not imported
0English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaSource mapped
Official source mapped; ingredient rule not imported
0English and Hindi
Saudi ArabiaSource mapped
Official source mapped; ingredient rule not imported
0Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 56-95-1
CAS 56-95-1PubChem CID 9562059

Chlorhexidine Acetate

Chlorhexidine acetate is the acetate salt of chlorhexidine. It is a disinfectant used for bacterial control in hospital, agricultural and domestic environments. It has a role as an antibacterial agent, an antiinfective agent, an antifungal agent and an antifouling biocide. It contains a chlorhexidine. ChEBI

IUPAC name
acetic acid;(1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine
Molecular formula
C26H38Cl2N10O4
Molecular weight
625.5 g/mol
Exact mass
624.2454551 Da
Topological polar surface area
252.0 Ų
Hydrogen-bond donors
8
Hydrogen-bond acceptors
6
Covalent units
3
Defined stereocentres
0

Also known as

Chlorhexidine diacetateHibitane diacetateChlorohexidine diacetate10,040 DiacetateChlorhexidini diacetas5908ZUF22YNSC-526936Chlorhexidine acetate (USP)
16 more reported names
Chlorhexidine acetate [USP]1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide) diacetateCHEBI:81711SerdaenGout OintmentBacteriostatic gelNail fungus creamanti-bacterial gelAntibacterialTabletsNail Fungus LiquidNail Fungus SolutionAcetate, ChlorhexidineFROST-PROOFNolvasan Surgical ScrubHOQU Nail fungus creamDisinfectant Fabric Wash
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CHLORHEXIDINE DIACETATE

INCI name

CHLORHEXIDINE DIACETATE

Ph. Eur. name

chlorhexidini acetas

Description

N,N'-bis(4-Chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine di(acetate)

Record provenance

Inventory reference
32658
Imported identity
CHLORHEXIDINE DIACETATE
Source update
10/08/2020
European Commission CosIng source notes

Key data

Restriction
V/42
Function
ANTIMICROBIAL
Preventing and/or slowing down microbial growth.
ORAL CARE
Providing cosmetic effects to the oral cavity, e.g. cleansing, deodorising, protecting.
PRESERVATIVE
Exclusively or mainly intended to inhibit the development of micro-organisms in the cosmetic product. All authorised preservatives are substances in the positive list of Annex V to the Cosmetics Regulation 1223/2009.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How CHLORHEXIDINE DIACETATE appears in the CosIng inventory

The CosIng inventory lists CHLORHEXIDINE DIACETATE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CHLORHEXIDINE DIACETATE is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CHLORHEXIDINE DIACETATE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for CHLORHEXIDINE DIACETATE reads: "V/42". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, CHLORHEXIDINE DIACETATE carries the following function designation(s):

CAS 56-95-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for CHLORHEXIDINE DIACETATE

This page combines the CosIng inventory entry for CHLORHEXIDINE DIACETATE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research CHLORHEXIDINE DIACETATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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