What does the restriction note for ACID YELLOW 73 SODIUM SALT mean?

The restriction field for ACID YELLOW 73 SODIUM SALT reads: II/1332 (when used as a substance in hair dye products). This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 518-47-8?

CAS 518-47-8 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains ACID YELLOW 73 SODIUM SALT?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3163912/08/2020

ACID YELLOW 73 SODIUM SALT

Disodium 2-(3-oxo-6-oxidoxanthen-9-yl)benzoate (CI 45350)

ACID YELLOW 73 SODIUM SALT is linked to 2 EU annex records on this page. Inventory note: II/1332 (when used as a substance in hair dye products).

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	2	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Prohibited + Permitted list with conditions Open this evidence	2	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 518-47-8

CAS 518-47-8PubChem CID 10608

Sodium Fluorescein

Fluorescein, disodium salt is an orange-red to dark red powder. Water-soluble form of fluorescein. Odorless and almost tasteless. pH (5% solution) 7.8. May be sensitive to prolonged exposure to light and to heat. — CAMEO Chemicals

IUPAC name: disodium;2-(3-oxido-6-oxoxanthen-9-yl)benzoate

Molecular formula: C20H10Na2O5
Molecular weight: 376.3 g/mol
Exact mass: 376.03236198 Da
Topological polar surface area: 89.5 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 5
Covalent units: 3
Defined stereocentres: 0

Also known as

Fluorescein disodium saltSoluble fluoresceinUraninUranine WSSResorcinol phthalein sodiumUranine YellowAk-FluorFluorescein, soluble

16 more reported names

Ki202Sodium fluoresceinateFluoresceinum natricum93X55PE38XD&C Yellow No. 8Funduscein-25Ki202(1)Ki202(2)D & C Yellow no. 8disodium 2-(6-oxido-3-oxo-3H-xanthen-9-yl)benzoateCI 45350CI 45350 (Na salt)3',6'-Dihydroxyspiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, disodium saltRetinofluorGlostripsBioglo

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEMBL:CHEMBL1628233

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ACID YELLOW 73 SODIUM SALT

INCI name

ACID YELLOW 73 SODIUM SALT

INN name

fluorescein sodium

Description

Disodium 2-(3-oxo-6-oxidoxanthen-9-yl)benzoate (CI 45350)

Record provenance

Inventory reference: 31639
Imported identity: ACID YELLOW 73 SODIUM SALT
Source update: 12/08/2020

European Commission CosIng source notes

Annex records for ACID YELLOW 73 SODIUM SALT

Annex II Restriction reference

Entry 1332

2-(6-Hydroxy-3-oxo-(3H)xanthen-9-yl)benzoic acid; Fluorescein and its disodium salt (Acid Yellow 73…

CAS: 2321-07-5 -- 518-47-8

EC: 219-031-8 -- 208-253-0

Annex IV Identified ingredient

Entry 74

CI 45350

CAS: 518-45-6; 518-47-8

EC: -; 208-253-0

Key data

CAS

518-47-8

208-253-0

Restriction

II/1332 (when used as a substance in hair dye products)

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#885 · ACID YELLOW 73 SODIUM SALT

Ingredients with overlapping formulation functions

ACID YELLOW 23HAIR DYEING

ACID YELLOW 23 ALUMINUM LAKEHAIR DYEING

ACID YELLOW 36HAIR DYEING

ACID YELLOW 73COLORANT, HAIR DYEING

BASIC BLUE 124HAIR DYEING

BASIC BLUE 26HAIR DYEING

BASIC BLUE 3HAIR DYEING

BASIC BLUE 41HAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ACID YELLOW 73 SODIUM SALT appears in the CosIng inventory

The CosIng inventory lists ACID YELLOW 73 SODIUM SALT as a cosmetic ingredient and this page links it to 2 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ACID YELLOW 73 SODIUM SALT is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ACID YELLOW 73 SODIUM SALT appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for ACID YELLOW 73 SODIUM SALT reads: "II/1332 (when used as a substance in hair dye products)". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, ACID YELLOW 73 SODIUM SALT carries the following function designation(s):

HAIR DYEING

CAS 518-47-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ACID YELLOW 73 SODIUM SALT

This page combines the CosIng inventory entry for ACID YELLOW 73 SODIUM SALT with 2 linked Annex II–VI records from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research ACID YELLOW 73 SODIUM SALT and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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