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Official EU label nameGlossary entry 8612

DIETHYLHEXYL PHTHALATE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 9 of 13 indexed market datasets: 9 country records and 0 EU Annex records. Every result and evidence gap is listed below.

9 markets with evidence
Markets checked
13
Markets with evidence
9
Evidence gaps
4
Resolved identifiers
2

A missing local match is not permission, approval or proof of safety. It means no strong identity match was resolved in that indexed dataset.

Resolved substance identity

CAS:117-81-7
EC:204-211-0
Ingredient index records:
DIETHYLHEXYL PHTHALATE
Cosmetic functions: FRAGRANCE, PERFUMING, PLASTICISER, SOLVENT

Inventory restriction note: II/677

Open full local profile
9 matched or reported names
DIETHYLHEXYL PHTHALATEbis(2-Ethylhexyl) phthalate (Diethylhexyl phthalate)Diethylhexyl phthalateBis(2-ethylhexyl) phthalate (diethylhexyl phthalate)bis(2-Ethylhexyl) phthalate邻苯二甲酸双（2-乙基己基）酯 — Bis （2-ethylhexyl） phthalate （Diethylhexyl phthalate） （CAS No. 117-81-7）Ftalato de bis(2-etilhexila)bis(2-Ethylhexyl) phthalate (Diethylhexyl phthalate) (CAS No. 117-81-7)bis(2-Ethylhexyl) phthalate; (Diethylhexyl phthalate)

Regulatory evidence in all 13 markets

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MarketResultRecordsDatasetMeaning / next action
European Union
EU
No local match0
Complete annex dataset
Regulation (EC) 1223/2009 consolidated to 1 May 2026
No annex match only means that these five annexes did not return a match; CosIng identity data and other EU obligations still need review.
Great Britain
GB
Prohibited1Open record 1
Complete consolidated annex dataset
GB retained Regulation 1223/2009 schedules, effective 15 August 2026
Review every linked record and exact conditions.
Canada
CA
Prohibited1Open record 1
Complete Hotlist snapshot
Health Canada Cosmetic Ingredient Hotlist, 13 August 2025
Review every linked record and exact conditions.
New Zealand
NZ
Prohibited1Open record 1
Complete schedules dataset
Cosmetic Products Group Standard schedules effective 1 January 2026
Review every linked record and exact conditions.
ASEAN
ASEAN
Prohibited1Open record 1
Complete regional annex dataset
ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026
Review every linked record and exact conditions.
China
CN
Prohibited1Open record 1
Complete prohibited catalogues plus official-source workflow
NMPA 2021 banned catalogues plus dynamic IECIC List I/List II system current since 2025
Review every linked record and exact conditions.
Japan
JP
No local match0
Complete Standards appendices dataset
MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshot
The Japanese text and subsequent notices are canonical; no local match is not a product-compliance conclusion.
South Korea
KR
No local match0
Complete current appendix dataset
MFDS Notice 2026-19, effective 18 March 2026
Korean source wording is canonical and other positive lists/notices may still apply to the formulation.
United States
US
No local match0
Complete enumerated federal ingredient rules
eCFR Title 21 issue date 27 August 2026
FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety.
Australia
AU
Prohibited1Open record 1
Complete cosmetic-relevant Poisons Standard subset plus official workflow
Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026
Review every linked record and exact conditions.
Brazil
BR
Prohibited1Open record 1
Complete prohibited dataset plus current restricted-list workflow
ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026
Review every linked record and exact conditions.
India
IN
Prohibited1Open record 1
Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4
Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022)
Review every linked record and exact conditions.
Saudi Arabia
SA
Prohibited1Open record 1
Complete official list index
SFDA live prohibited/restricted lists, snapshot 30 August 2026
Review every linked record and exact conditions.
No market rows match this filter.

Matching market records and conditions

Chemical identity and properties

PubChem 2D chemical structure for CAS 117-81-7
CAS 117-81-7PubChem CID 8343

Di(2-ethylhexyl) phthalate

Bis(2-ethylhexyl) phthalate is a phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid. It has a role as an apoptosis inhibitor, an androstane receptor agonist and a plasticiser. It is a phthalate ester and a diester. — ChEBI

IUPAC name
bis(2-ethylhexyl) benzene-1,2-dicarboxylate
Molecular formula
C24H38O4
Molecular weight
390.6 g/mol
Exact mass
390.27700969 Da
XLogP3
7.4
Topological polar surface area
52.6 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

Bis(2-ethylhexyl) phthalateDi(2-ethylhexyl)phthalateEtalonEthylhexyl phthalateVinicizer 80DioctylphthalateHercoflex 260Nuoplaz dop
16 more reported names
RC plasticizer DOPHatcol dopReomol dopSansocizer DOPErgoplast FDOMonocizer DOPPlasthall DOPMollan OPittsburgh PX-138Ergoplast FDO-SGood-rite gp 264Sconamoll DOPDiacizer DOPDi(2-ethylhexyl)orthophthalateEtalon (plasticizer)Behp
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match8343

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknow Source: CAMEO Chemicals
  • First Aid: (General first aid procedures); Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Breathing: Respiratory support; Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately. Source: The National Institute for Occupational Safety and Health (NIOSH)
  • Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H360FD: May damage fertility; May damage the unborn child [Danger Reproductive toxicity] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P203, P280, P318, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Note: This chemical does not meet GHS hazard criteria for < 0.1% (1 of 1071) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H360 (94.5%): May damage fertility or the unborn child [Danger Reproductive toxicity] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P203, P280, P318, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 1071 reports by companies from 27 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 1 of 1071 reports by companies.; There are 26 notifications provided by 1070 of 1071 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H320: Causes eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H351: Suspected of causing cancer [Warning Carcinogenicity]; H360: May damage fertility or the unborn child [Danger Reproductive toxicity]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P203, P260, P261, P264+P265, P271, P273, P280, P304+P340, P305+P351+P338, P318, P319, P337+P317, P391, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • GHS Hazard Statements: Not Classified Source: NITE-CMC
  • Health Effects: Chronic and/or high levels of DEHP exposure may cause reproductive and developmental damage. This includes damaged sperm, delayed sexual maturity, and deficiencies in the development of male babies. DEHP may also cause liver and kidney damage, and is potentially carcinogenic. (L181, L182) Source: Toxin and Toxin Target Database (T3DB)
  • Toxicity Summary: IDENTIFICATION AND USE: Di(2-ethylhexyl)phthalate (DEHP) is a colorless, oily liquid. Plastics may contain from 1 to 40% DEHP by weight and are used in consumer products such as imitation leather, rainwear, footwear, upholstery, flooring, wire and cable, tablecloths, shower curtains, food packaging materials and children's toys. DEHP is also used as a hydraulic fluid and as a dielectric fluid (a non-conductor of electric current) in electrical capacitors, a detector for leaks in respirators. DEHP is not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses. HUMAN EXPOSURE AND TOXICITY: DEHP has been found in various types of food, such as fish, shellfish, eggs and cheese. Blood transfusions and other medical treatment using plastic devices may lead to involuntary human exposure to DEHP. Available data on oral administration indicate that DEHP is hydrolyzed in the gut by pancreatic lipase. The metabolites formed, i.e., mono(2-ethylhexyl)phthalate and 2-ethyl hexanol, are rapidly absorbed. Mono-2-ethylhexyl phthalate was detected in human teeth. When adminis Source: Hazardous Substances Data Bank (HSDB)
  • Toxicity Summary: Monoethylhexylphthalate (MEHP), one of the major metabolites of DEHP, induces peroxisome proliferation by activating peroxisome proliferator activated receptors. This is believed to increase production of hydrogen peroxide by peroxisomes and enhance cell proliferation, leading to hepatotoxic and carcinogenic effects. MEHP is also believed to exhibit testicular toxicity by targeting and damaging the Sertoli cells. DEHP may act as an antiandrogen during a critical stage of reproductive tract differentiation by reducing testosterone in fetal males, hindering development. (L181, A106) Source: Toxin and Toxin Target Database (T3DB)
  • Environmental Bioconcentration: Experimental BCF values range from a log 2 to 4 in fish and invertebrates(1-7). Log BCFs of 2.93 and 2.06 were measured in fathead minnows (Pimephales promelas)(2) and bluegill sunfish (Lepomis macrochirus), respectively(3). BCF values of <0.7-29.7 and 1-3.4 were reported using carp (Cyprinus carpio) which were exposed over an 8-week period to bis(2-ethylhexyl) phthalate concentrations of 0.1 and 1.0 ppm, respectively(8). According to a classification scheme(9), these BCFs suggest that bioconcentration in aquatic organisms is low to very high(SRC). Experiments with rainbow trout (Salmo gairdneri) showed that the majority of (14)C-bis(2-ethylhexyl) phthalate did not reach the systemic circulation of the fish, but was present in the exposure water as metabolites as a result of pre-systemic branchial metabolism of this compound during uptake from the water to the blood(10). Biota-sediment accumulation factors were 1.0, 0.5 and 1.3 in roach (Rutilus rutilus), chub (Leuciscus cephalus) and perch (Perca fluviatilis), respectively; fish were collected from the Orge River, France from Jul 2009 to Apr 2010(11). BCFs of 0.02-0.11 were reported for bis(2-ethylhexyl) phthalate in water spinach Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Bioconcentration: Bis(2-ethylhexyl) phthalate bioconcentration factor for rainbow trout: 42-113; duration, 36 days, whole body. Bioconcentration factor for fathead minnow 155-886; duration, 56 days, whole body. Bioconcentration factor for Gammarus pseudolimnaeus (scud): 54-2,680 (from dry to wet weight); duration, 14-21 days, whole body. Bioconcentration factor for Aselius brevicaudus (sowbug): 14-50 (from dry to wet weight); duration, 21 days, whole body. Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), Koc values ranging from 87,420(2) to 510,000(3), indicate that bis(2-ethylhexyl) phthalate is expected to be immobile in soil(SRC). Volatilization of bis(2-ethylhexyl) phthalate from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 2.7X10-7 atm-cu m/mole(SRC), based upon its vapor pressure, 1.42X10-7 mm Hg(4), and water solubility, 0.27 mg/L(5). Bis(2-ethylhexyl) phthalate is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(4). Mineralization rates of 15 to 50% remaining after 80 days(6) and 22 to 32% (14)CO2 in three soils after 60 days incubation(7) suggest that biodegradation proceeds slowly in soil environments(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), Koc values ranging from 87,420(2) to 510,000(3), indicate that bis(2-ethylhexyl) phthalate is expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(4) based upon an estimated Henry's Law constant of 2.7X10-7 atm-cu m/mole(SRC), derived from its vapor pressure, 1.42X10-7 mm Hg(5), and water solubility, 0.27 mg/L(6). Bis(2-ethylhexyl) phthalate is not expected to undergo hydrolysis in the environment based on an aqueous hydrolysis half-life of 2000 years that was determined at pH 7(3). According to a classification scheme(7), BCF values of <0.1(8) to 850(9) in carp, bluegill and fathead minnows, suggest bioconcentration in aquatic organisms is low to very high; this range may indicate the ability of aquatic organisms to readily metabolize this class of compounds(3). In unacclimated aquatic systems no biodegradation was observed(10), but a biodegradation half-life of 60 to 70 hours in groundwater impacted by bis(2-ethylhexyl) phthalate was reported(11), suggesting that biodegradation is dependent to a large extent on acclimation of aquatic environments(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), bis(2-ethylhexyl) phthalate, which has a vapor pressure of 1.42X10-7 mm Hg at 25 °C(2), will exist in both the vapor and particulate phases in the ambient atmosphere. Vapor-phase bis(2-ethylhexyl) phthalate is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 16 hours(SRC), calculated from its rate constant of 2.2X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Particulate-phase bis(2-ethylhexyl) phthalate may be removed from the air by wet and dry deposition(SRC). Bis(2-ethylhexyl) phthalate contains chromophores that absorb at wavelengths >290 nm(4) and, therefore, may be susceptible to direct photolysis by sunlight(SRC). Gas-phase hydroxyl radicals reacted with bis(2-ethylhexyl) phthalate adsorbed onto silicon dioxide, aluminum oxide, iron(III) oxide and coal fly ash(5), exhibiting half-lives of 1.1, 1.2, 1.3 and 2.0 days, respectively(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Congress has permanently banned three types of phthalates (DEHP, DBP, BBP) in any amount greater than 0.1 percent (computed for each phthalate, individually) in (1) children's toys and (2) certain child care articles. di-(2-ethylhexyl) phthalate (DEHP), dibutyl phthalate (DBP), or benzyl butyl phthalate (BBP). Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For bis(2-ethylhexylphthalate) (USEPA/OPP Pesticide Code: 295200) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: The active ingredient is no longer contained in any registered pesticide products ... "cancelled." Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Plastics may contain from 1 to 40% di(2-ethylhexyl) phthalate by weight and are used in consumer products such as imitation leather, rainwear, footwear, upholstery, flooring, wire and cable, tablecloths, shower curtains, food packaging materials and children's toys. ... Di(2-ethylhexyl) phthalate is also used as a hydraulic fluid and as a dielectric fluid (a non-conductor of electric current) in electrical capacitors. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for BIS(2-ETHYLHEXYL) PHTHALATE (19 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Plastics -> Typical concentration range in plastic materials -> 2.0 - 35.0% Source: NORMAN Suspect List Exchange
  • Uses: DEHP is present in plastic products such as wall coverings, tablecloths, floor tiles, furniture upholstery, shower curtains, garden hoses, swimming pool liners, rainwear, baby pants, dolls, some toys, shoes, automobile upholstery and tops, packaging film and sheets, sheathing for wire and cable, medical tubing, and blood storage bags. (L181) Source: Toxin and Toxin Target Database (T3DB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

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Cosmetic Ingredient Review safety assessments

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Japan NITE-CHRIP

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Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

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NIOSH Pocket Guide to Chemical Hazards

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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