Official EU label nameGlossary entry 7584

CREATINE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:57-00-16020-87-7

EC:200-306-6

Ingredient index records:

CREATINE

Cosmetic functions: SKIN CONDITIONING

Glycine, N-(Aminoiminomethyl)-N-Methyl-

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1 matched or reported name

CREATINE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name CREATINE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 57-00-1

CAS 57-00-1PubChem CID 586

Creatine

Creatine is a glycine derivative having methyl and amidino groups attached to the nitrogen. It has a role as a geroprotector, a nutraceutical, a neuroprotective agent, a mouse metabolite and a human metabolite. It is a glycine derivative and a member of guanidines. It is a conjugate acid of a creatinate. It is a tautomer of a creatine zwitterion. — ChEBI

IUPAC name: 2-[carbamimidoyl(methyl)amino]acetic acid

Molecular formula: C4H9N3O2
Molecular weight: 131.13 g/mol
Exact mass: 131.069476538 Da
XLogP3: -1.2
Topological polar surface area: 90.4 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

CreatinN-amidinosarcosineKreatinKrebiozonmethylglycocyamineN-methyl-N-guanylglycineGlycine, N-(aminoiminomethyl)-N-methyl-Pyrolysate

16 more reported names

(alpha-Methylguanido)acetic acidN-carbamimidoyl-N-methylglycineCosmocair C 100KreatinumNeotine2-(1-methylcarbamimidamido)acetic acidN-(aminoiminomethyl)-N-methylglycinealpha-Methylguanidino acetic acidNSC-8752(N-methylcarbamimidamido)acetic acid((amino(imino)methyl)(methyl)amino)acetic acidN-[(E)-AMINO(IMINO)METHYL]-N-METHYLGLYCINECHEBI:169192-(carbamimidoyl(methyl)amino)acetic acid[[Amino(imino)methyl](methyl)amino]acetic acidN-((E)-AMINO(IMINO)METHYL)-N-METHYLGLYCINE

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External database identifiers

ChEBI:CHEBI:16919
ChEMBL:CHEMBL283800
EPA DTXSID:DTXSID1040451
PubMed:33124720
PubMed:33022268
PubMed:29968805
PubMed:28558019
PubMed:24709313
PubMed:23125906
PubMed:23120950
PubMed:23117948
PubMed:23117947
PubMed:23115480
PubMed:23115467
PubMed:23112907

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 6020-87-7

CAS 6020-87-7PubChem CID 80116

Creatine Monohydrate

Creatine Monohydrate is the monohydrate form of creatine similar or identical to endogenous creatine produced in the liver, kidneys, and pancreas. Creatine, in phosphate form, helps supply energy to muscle cells for contraction. After intense effort, when ATP deposits are depleted, creatine phosphate donates phosphate groups toward the fast synthesis of ATP. Dietary supplementation with creatine may improve muscle wasting associated with cancer and other chronic diseases. — NCI Thesaurus (NCIt)

IUPAC name: 2-[carbamimidoyl(methyl)amino]acetic acid;hydrate

Molecular formula: C4H11N3O3
Molecular weight: 149.15 g/mol
Exact mass: 149.08004122 Da
Topological polar surface area: 91.4 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 4
Covalent units: 2
Defined stereocentres: 0

Also known as

Creatine, monohydrateCreapureGlycine, N-(aminoiminomethyl)-N-methyl-, monohydrateUNII-9603LN7R2Q9603LN7R2QN-(Aminoiminomethyl)-N-methylglycine monohydrateCREATINE MONOHYDRATE [WHO-DD]Glycine, N-(aminoiminomethyl)-N-methyl-, hydrate (1:1)

16 more reported names

Creatine SupplementRefChem:128421N-(aminoiminomethyl)-N-methyl-Glycine, monohydrate611-954-82-(1-Methylguanidino)acetic acid hydrateCreatine hydrateCreatine (monohydrate)N-Guanyl-N-methylglycinecreatine-monohydrateCreatine (hydrate)Glycine, N-(aminoiminomethyl)-N-methyl-, hydrate (1:1); Creatine, monohydrate (8CI); Glycine, N-(aminoiminomethyl)-N-methyl-, monohydrate (9CI); CreapureCreatine monohydrate, >=98%Methylguanidoacetic acid monohydrates6023CS-W018178DS-9420

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External database identifiers

ChEMBL:CHEMBL5275950
EPA DTXSID:DTXSID10208954

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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