Official EU label nameGlossary entry 7547

COUMAROYL METHOXYTRYPTAMINE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:366452-03-1

Ingredient index records:

COUMAROYL METHOXYTRYPTAMINE

Cosmetic functions: SKIN CONDITIONING

Hydroxycinnamoyl Methoxytryptamine,2-Propenamide, 3-(4-hydroxyphenyl)-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-,(2E)-

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1 matched or reported name

COUMAROYL METHOXYTRYPTAMINE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name COUMAROYL METHOXYTRYPTAMINE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 366452-03-1

CAS 366452-03-1PubChem CID 636923

Centcyamine

coumaroyl methoxytryptamine has been reported in Centaurea cyanus and Centaurea montana with data available. — LOTUS - the natural products occurrence database

IUPAC name: (E)-3-(4-hydroxyphenyl)-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]prop-2-enamide

Molecular formula: C20H20N2O3
Molecular weight: 336.4 g/mol
Exact mass: 336.14739250 Da
XLogP3: 2.5
Topological polar surface area: 74.4 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

ClotholineCoumaroyl methoxytryptamineUNII-HE37GBK28QCoumaroyl methoxytryptamine, (E)-HE37GBK28QCoumaroyl methoxytryptamine [INCI](E)-N-(4-hydroxycinnamoyl)-5-methoxytryptamine(2E)-3-(4-hydroxyphenyl)-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acrylamide

10 more reported names

3-(4-Hydroxy-phenyl)-N-[2-(5-methoxy-1H-indol-3-yl)-ethyl]-acrylamide(2E)-3-(4-hydroxyphenyl)-N-(2-(5-methoxy-1H-indol-3-yl)ethyl)acrylamide3-(4-Hydroxy-phenyl)-N-(2-(5-methoxy-1H-indol-3-yl)-ethyl)-acrylamide(E)-3-(4-hydroxyphenyl)-N-(2-(5-methoxy-1H-indol-3-yl)ethyl)prop-2-enamideRefChem:124336InChI=1/C20H20N2O3/c1-25-17-7-8-19-18(12-17)15(13-22-19)10-11-21-20(24)9-4-14-2-5-16(23)6-3-14/h2-9,12-13,22-23H,10-11H2,1H3,(H,21,24)/b9-42-Propenamide, 3-(4-hydroxyphenyl)-N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-, (2E)-2-propenamide, 3-(4-hydroxyphenyl)-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-, (2E)-DAYQHEUNAQSDHV-RUDMXATFSA-N(E)-3-(4-hydroxyphenyl)-N-(2-(5-methoxy-1H-indol-3-yl)ethyl) acrylamide

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Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

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Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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