What other records share CAS 366452-03-1?

CAS 366452-03-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains COUMAROYL METHOXYTRYPTAMINE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9191918/09/2014

COUMAROYL METHOXYTRYPTAMINE

Hydroxycinnamoyl Methoxytryptamine,2-Propenamide, 3-(4-hydroxyphenyl)-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-,(2E)-

COUMAROYL METHOXYTRYPTAMINE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

INCI Checker Compare all markets Search similar

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Markets and their official sources Search every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 366452-03-1

CAS 366452-03-1PubChem CID 636923

Centcyamine

coumaroyl methoxytryptamine has been reported in Centaurea cyanus and Centaurea montana with data available. — LOTUS - the natural products occurrence database

IUPAC name: (E)-3-(4-hydroxyphenyl)-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]prop-2-enamide

Molecular formula: C20H20N2O3
Molecular weight: 336.4 g/mol
Exact mass: 336.14739250 Da
XLogP3: 2.5
Topological polar surface area: 74.4 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

ClotholineCoumaroyl methoxytryptamineUNII-HE37GBK28QCoumaroyl methoxytryptamine, (E)-HE37GBK28QCoumaroyl methoxytryptamine [INCI](E)-N-(4-hydroxycinnamoyl)-5-methoxytryptamine(2E)-3-(4-hydroxyphenyl)-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acrylamide

10 more reported names

3-(4-Hydroxy-phenyl)-N-[2-(5-methoxy-1H-indol-3-yl)-ethyl]-acrylamide(2E)-3-(4-hydroxyphenyl)-N-(2-(5-methoxy-1H-indol-3-yl)ethyl)acrylamide3-(4-Hydroxy-phenyl)-N-(2-(5-methoxy-1H-indol-3-yl)-ethyl)-acrylamide(E)-3-(4-hydroxyphenyl)-N-(2-(5-methoxy-1H-indol-3-yl)ethyl)prop-2-enamideRefChem:124336InChI=1/C20H20N2O3/c1-25-17-7-8-19-18(12-17)15(13-22-19)10-11-21-20(24)9-4-14-2-5-16(23)6-3-14/h2-9,12-13,22-23H,10-11H2,1H3,(H,21,24)/b9-42-Propenamide, 3-(4-hydroxyphenyl)-N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-, (2E)-2-propenamide, 3-(4-hydroxyphenyl)-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-, (2E)-DAYQHEUNAQSDHV-RUDMXATFSA-N(E)-3-(4-hydroxyphenyl)-N-(2-(5-methoxy-1H-indol-3-yl)ethyl) acrylamide

Open full PubChem record PubChem annotations 3D structure image

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for COUMAROYL METHOXYTRYPTAMINE

INCI name

COUMAROYL METHOXYTRYPTAMINE

Description

Hydroxycinnamoyl Methoxytryptamine,2-Propenamide, 3-(4-hydroxyphenyl)-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-,(2E)-

Record provenance

Inventory reference: 91919
Imported identity: COUMAROYL METHOXYTRYPTAMINE
Source update: 18/09/2014

European Commission CosIng source notes

Annex records for COUMAROYL METHOXYTRYPTAMINE

Browse

Browse EU annexes

Explore Annex II–VI to see which substances are prohibited, restricted or permitted under specific conditions.

Search annex entries

Search the annex database for entries matching COUMAROYL METHOXYTRYPTAMINE or related substances.

Key data

CAS

366452-03-1

—

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#7547 · COUMAROYL METHOXYTRYPTAMINE

Ingredients with overlapping formulation functions

COTTONSEED OIL/PALM OIL AMINOPROPANEDIOL ESTERSSKIN CONDITIONING

COUMARAMIDO FERULAMIDOBUTANESKIN CONDITIONING

COUMAROYL DIPEPTIDE-3SKIN CONDITIONING, SKIN PROTECTING

COUMAROYL HEXAPEPTIDE-77SKIN CONDITIONING, SKIN PROTECTING

COW BLOOD CLOT EXTRACTHAIR CONDITIONING, SKIN CONDITIONING

COW COLOSTRUM EXTRACTHUMECTANT, SKIN CONDITIONING

COW PLATELETSSKIN CONDITIONING

CRAMBE ABYSSINICA SEED OILHAIR CONDITIONING, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How COUMAROYL METHOXYTRYPTAMINE appears in the CosIng inventory

The CosIng inventory lists COUMAROYL METHOXYTRYPTAMINE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

COUMAROYL METHOXYTRYPTAMINE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

COUMAROYL METHOXYTRYPTAMINE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, COUMAROYL METHOXYTRYPTAMINE carries the following function designation(s):

SKIN CONDITIONING

CAS 366452-03-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

View CAS records

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Open INCI Checker

Source note for COUMAROYL METHOXYTRYPTAMINE

This page reproduces the CosIng inventory entry for COUMAROYL METHOXYTRYPTAMINE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research COUMAROYL METHOXYTRYPTAMINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

View sources View updates

Tools & next steps

Check your formula

Scan a full INCI list to detect COUMAROYL METHOXYTRYPTAMINE and any linked EU annex restrictions or allergen flags.

INCI Checker

Search similar ingredients

Find other inventory ingredients and annex entries related to COUMAROYL METHOXYTRYPTAMINE, its identifiers or nearby name variants.