Official EU label nameGlossary entry 666

ACETYL HISTIDINE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence

Markets checked

Markets with evidence

Evidence gaps

Resolved identifiers

Resolved substance identity

CAS:2407-02-139145-52-3

EC:219-678-6

Ingredient index records:

ACETYL HISTIDINE

Cosmetic functions: HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

L-Histidine, N-Acetyl-,

Open full local profile

1 matched or reported name

ACETYL HISTIDINE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name ACETYL HISTIDINE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

Check the markets and their sources Search every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 39145-52-3

CAS 39145-52-3PubChem CID 2724380

N-acetylhistidine monohydrate

The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Acetyl Histidine — Cosmetic Ingredient Review (CIR)

IUPAC name: (2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoic acid;hydrate

Molecular formula: C8H13N3O4
Molecular weight: 215.21 g/mol
Exact mass: 215.09060590 Da
Topological polar surface area: 96.1 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 5
Covalent units: 2
Defined stereocentres: 1

Also known as

Acetyl histidineN-Acetyl-L-histidine hydrateL-Histidine, N-acetyl-, monohydrateL-N-acetylhistidine monohydratePQ2TC3X11ORefChem:199350ac-his-oh.h2oN-Acetyl-L-histidine Monohydrate

16 more reported names

Ac-His-OH H2ON-Acetyl-L-histidine (monohydrate)(2S)-2-(Acetylamino)-3-(1H-imidazol-4-yl)propanoic acid hydrateN-Acetyl-L-histidine MonohydrateUNII-PQ2TC3X11OAc-L-His-OH.H2Oacetylhistidine monohydrateacetyl-L-histidine hydratePSWSDQRXCOJSFC-FJXQXJEOSA-N(2S)-2-ACETAMIDO-3-(1H-IMIDAZOL-4-YL)PROPANOIC ACID HYDRATECS-W014896HY-W014180AS-49156EN300-198771L-HISTIDINE, N-ACETYL-, HYDRATE (1:1)(2S)-2-(acetylamino)-3-imidazol-4-ylpropanoic acid, hydrate

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID901021292

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

Take this record further

Screen in a formula Open standalone comparison

Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

Open official Decision