Official EU label nameGlossary entry 6211
CHLORHEXIDINE
This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.
Global evidence snapshot
The resolved identity has matching regulatory evidence in 6 of 13 indexed market datasets: 6 country records and 0 EU Annex records. Every result and evidence gap is listed below.
Markets checked
13
Markets with evidence
6
Evidence gaps
7
Resolved identifiers
8
Resolved substance identity
CAS:55-56-156-95-118472-51-03697-42-5
EC:200-238-7200-302-4242-354-0223-026-6
Ingredient index records:
CHLORHEXIDINE
Cosmetic functions: ANTIMICROBIAL, ORAL CARE, PRESERVATIVE
2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-; Biguanide, 1,1'-hexamethylenebis(5-(p-chlorophenyl)-
Inventory restriction note: V/42
8 matched or reported names
CHLORHEXIDINEchlorhexidineChlorhexidine, Chlorhexidine Diacetate, Chlorhexidine Digluconate, Chlorhexidine DihydrochlorideChlorhexidine and its saltsN,N″-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13tetraazatetradecanediamidine (chlorhexidine) and its digluconate, diacetate, and dihydrochloride e.g. chlorhexidineChlorhexidine (INN) and its digluconate, diacetate and dihydrochloride (+) Chlorhexidine (CAS No. 55-56-1), Chlorhexidine diacetate (CAS No. 56- 95-1), Chlorhexidine digluconate, Chlorhexidine dihydrochloride (CAS No. 3697-42-5)Chlorhexidine클로헥시딘, 그 디글루코네이트, 디아세테이트 및 디하이드로클로라이드
Regulatory evidence in all 13 markets
Open each matched record for its scope, concentration, conditions, warnings and official source version.
Swipe or scroll horizontally to see dataset coverage and next actions.
| Market | Result | Records | Dataset | Meaning / next action |
|---|---|---|---|---|
| European Union EU | No local match | 0 | Complete annex dataset Regulation (EC) 1223/2009 consolidated to 1 May 2026 | No annex match only means that these five annexes did not return a match; CosIng identity data and other EU obligations still need review. |
| Great Britain GB | Permitted list with conditions | 1Open record 1 | Complete consolidated annex dataset GB retained Regulation 1223/2009 schedules, effective 15 August 2026 | Review every linked record and exact conditions. |
| Canada CA | Restricted | 1Open record 1 | Complete Hotlist snapshot Health Canada Cosmetic Ingredient Hotlist, 13 August 2025 | Review every linked record and exact conditions. |
| New Zealand NZ | Permitted list with conditions | 1Open record 1 | Complete schedules dataset Cosmetic Products Group Standard schedules effective 1 January 2026 | Review every linked record and exact conditions. |
| ASEAN ASEAN | Permitted list with conditions | 1Open record 1 | Complete regional annex dataset ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026 | Review every linked record and exact conditions. |
| China CN | No local match | 0 | Complete prohibited catalogues plus official-source workflow NMPA 2021 banned catalogues plus dynamic IECIC List I/List II system current since 2025 | IECIC listing is not blanket approval; absence may require the new cosmetic ingredient route, and restrictions are checked separately. |
| Japan JP | Restricted | 1Open record 1 | Complete Standards appendices dataset MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshot | Review every linked record and exact conditions. |
| South Korea KR | Restricted | 1Open record 1 | Complete current appendix dataset MFDS Notice 2026-19, effective 18 March 2026 | Review every linked record and exact conditions. |
| United States US | No local match | 0 | Complete enumerated federal ingredient rules eCFR Title 21 issue date 27 August 2026 | FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety. |
| Australia AU | No local match | 0 | Complete cosmetic-relevant Poisons Standard subset plus official workflow Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026 | An AICIS Inventory match is not cosmetic approval; no Inventory match can indicate a new, exempted, reported or confidential introduction. |
| Brazil BR | No local match | 0 | Complete prohibited dataset plus current restricted-list workflow ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026 | RDC 1.030/2026 amends rather than replaces the prohibited baseline, and the second restricted-list revision was still under consultation in July 2026. |
| India IN | No local match | 0 | Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4 Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022) | The standards are separate controlled publications; absence from a locally indexed excerpt is not permission. |
| Saudi Arabia SA | No local match | 0 | Complete official list index SFDA live prohibited/restricted lists, snapshot 30 August 2026 | No list match is not permission; Gulf/SFDA product, claim, notification and technical requirements still apply. |
No market rows match this filter.
Matching market records and conditions
Canada
Health Canada Cosmetic Ingredient Hotlist, 13 August 2025New Zealand
Cosmetic Products Group Standard schedules effective 1 January 2026ASEAN
ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026Japan
MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshotSouth Korea
MFDS Notice 2026-19, effective 18 March 2026Chemical identity and properties
CAS 18472-51-0PubChem CID 9552081
Chlorhexidine Gluconate
Chlorhexidine gluconate is a D-gluconate adduct and an organochlorine compound. It has a role as an antibacterial agent. It is functionally related to a chlorhexidine. — ChEBI
- IUPAC name
- (1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine;bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid)
- Molecular formula
- C34H54Cl2N10O14
- Molecular weight
- 897.8 g/mol
- Exact mass
- 896.3198018 Da
- Topological polar surface area
- 454.0 Ų
- Hydrogen-bond donors
- 18
- Hydrogen-bond acceptors
- 16
- Covalent units
- 3
- Defined stereocentres
- 8
Also known as
CHLORHEXIDINE DIGLUCONATEHibiclensDyna-hexBioscrubHibistatMicrodermPeriochipPeriogard
16 more reported names
ExidineChlorhexidine D-digluconateBrian CareSteri-StatCida-StatBacticlensCorsodylHibidilKleersightPrevacarePharmaseal Scrub CareCHG SCRUBFight bacPrevacare RChlorhexidine di-D-gluconateMOR84MUD8E
External database identifiers
- ChEBI:CHEBI:28312
- ChEMBL:CHEMBL4297088
- EPA DTXSID:DTXSID5034519
- PubMed:33358762
- PubMed:23551508
- PubMed:22615282
- PubMed:18245686
- PubMed:16566965
- PubMed:15324357
- PubMed:10321611
- PubMed:9759061
- PubMed:2465403
- PubMed:1191923
- PubMed:1009330
- PubMed:145039
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 3697-42-5PubChem CID 9571016
Chlorhexidine Hydrochloride
Chlorhexidine hydrochloride is a member of guanidines. — ChEBI
- IUPAC name
- (1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine;dihydrochloride
- Molecular formula
- C22H32Cl4N10
- Molecular weight
- 578.4 g/mol
- Exact mass
- 578.153602 Da
- Topological polar surface area
- 178.0 Ų
- Hydrogen-bond donors
- 8
- Hydrogen-bond acceptors
- 2
- Covalent units
- 3
- Defined stereocentres
- 0
Also known as
Chlorhexidine dihydrochlorideChlorhexidine HClDantroche hibitaneAY-5312E64XL9U38KNSC-7566792,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-, dihydrochlorideChlorhex hcl
16 more reported names
1,1'-Hexamethylenebis(5-(4-chlorophenyl)biguanide) dihydrochloride1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide] DihydrochlorideNolvasan Cap-TabsNolvasan SuspensionRefChem:54790Hydrochloride, Chlorhexidine223-026-6Chlorhexidine 2HClArlacide HCaswell No. 481FChlorhexidine (dihydrochloride)Chlorhexidinium dichloride1,1'-Hexamethylenebis(5-(p-chlorophenyl)biguanide) dihydrochlorideEINECS 223-026-6EPA Pesticide Chemical Code 481700UNII-E64XL9U38K
External database identifiers
- ChEBI:CHEBI:31393
- ChEMBL:CHEMBL1484251
- EPA DTXSID:DTXSID7047144
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 55-56-1PubChem CID 9552079
Chlorhexidine
Chlorhexidine is a bisbiguanide compound with a structure consisting of two (p-chlorophenyl)guanide units linked by a hexamethylene bridge. It has a role as an antibacterial agent and an antiinfective agent. It is a member of biguanides and a member of monochlorobenzenes. It is functionally related to a biguanide. — ChEBI
- IUPAC name
- (1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine
- Molecular formula
- C22H30Cl2N10
- Molecular weight
- 505.4 g/mol
- Exact mass
- 504.2031964 Da
- XLogP3
- 0.1
- Topological polar surface area
- 178.0 Ų
- Hydrogen-bond donors
- 6
- Hydrogen-bond acceptors
- 2
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
HexadolSoretolFimeilSterilonTubulicidChlorhexidinumChlorhexidinClorhexidina
16 more reported names
CloresidinaNolvasanMerfen-incoloreChlorhexadineDentisept1,6-Bis(p-chlorophenyldiguanido)hexane1,6-Di(4'-chlorophenyldiguanido)hexane1,6-Bis(5-(p-chlorophenyl)biguandino)hexane1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide)R4KO0DY52LCHEBI:36141,6-Di(N-p-chlorophenyldiguanido)hexane2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamideN-(4-chlorophenyl)-1-3-(6-{N-[3-(4-chlorophenyl)carbamimidamidomethanimidoyl]amino}hexyl)carbamimidamidomethanimidamideclorexidina
External database identifiers
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 56-95-1PubChem CID 9562059
Chlorhexidine Acetate
Chlorhexidine acetate is the acetate salt of chlorhexidine. It is a disinfectant used for bacterial control in hospital, agricultural and domestic environments. It has a role as an antibacterial agent, an antiinfective agent, an antifungal agent and an antifouling biocide. It contains a chlorhexidine. — ChEBI
- IUPAC name
- acetic acid;(1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine
- Molecular formula
- C26H38Cl2N10O4
- Molecular weight
- 625.5 g/mol
- Exact mass
- 624.2454551 Da
- Topological polar surface area
- 252.0 Ų
- Hydrogen-bond donors
- 8
- Hydrogen-bond acceptors
- 6
- Covalent units
- 3
- Defined stereocentres
- 0
Also known as
Chlorhexidine diacetateHibitane diacetateChlorohexidine diacetate10,040 DiacetateChlorhexidini diacetas5908ZUF22YNSC-526936Chlorhexidine acetate (USP)
16 more reported names
Chlorhexidine acetate [USP]1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide) diacetateCHEBI:81711SerdaenGout OintmentBacteriostatic gelNail fungus creamanti-bacterial gelAntibacterialTabletsNail Fungus LiquidNail Fungus SolutionAcetate, ChlorhexidineFROST-PROOFNolvasan Surgical ScrubHOQU Nail fungus creamDisinfectant Fabric Wash
External database identifiers
- ChEBI:CHEBI:81711
- ChEMBL:CHEMBL486819
- EPA DTXSID:DTXSID7032345
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Additional authoritative substance research
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Official source and scope
Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.
Open official Decision