Official EU label nameGlossary entry 4959

CALCIUM PCA

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:31377-05-6

EC:250-602-4

Ingredient index records:

CALCIUM PCA

Cosmetic functions: HUMECTANT, SKIN CONDITIONING

L-Proline, 5-Oxo, Calcium Salt (2:1)

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1 matched or reported name

CALCIUM PCA

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name CALCIUM PCA.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 31377-05-6

CAS 31377-05-6PubChem CID 14559044

Calcium pidolate

The CIR Expert Panel concluded that PCA (i.e., 2-pyrrolidone-5-carboxylic acid), calcium PCA, magnesium PCA, potassium PCA, and sodium PCA are safe in cosmetics in the present practices of use and concentration described in this safety assessment. PCA and its salts should not be used in cosmetic products in which N-nitroso compounds can be formed. — Cosmetic Ingredient Review (CIR)

IUPAC name: calcium bis((2S)-5-oxopyrrolidine-2-carboxylate)

Molecular formula: C10H12CaN2O6
Molecular weight: 296.29 g/mol
Exact mass: 296.0321270 Da
Topological polar surface area: 138.0 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 6
Covalent units: 3
Defined stereocentres: 2

Also known as

Efical7Y2LVU5EKKCALCIDONECALCIUM PCARefChem:122896250-602-4Calcium (S)-5-oxopyrrolidine-2-carboxylatecalcium;(2S)-5-oxopyrrolidine-2-carboxylate

15 more reported names

Calcium bis(5-oxo-L-prolinate)UNII-7Y2LVU5EKKEINECS 250-602-4Ibercal (TN)CALCIUM OXOPROLINEL-CALCIUM PIDOLATECALCIUM L-PYROGLUTAMATECALCIUM PIDOLATE [MART.]CALCIUM PIDOLATE [WHO-DD]5-OXO-L-PROLINE CALCIUM SALTPIDOLIC ACID CALCIUM SALT (2:1)Calcium bis[(2S)-5-oxopyrrolidine-2-carboxylate]L-PROLINE, 5-OXO-, CALCIUM SALT (2:1)L-PYRROLIDONE CARBOXYLIC ACID, CALCIUM SALTPROLINE, 5-OXO-, CALCIUM SALT (2:1), L-

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External database identifiers

EPA DTXSID:DTXSID501019893

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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