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Official EU label nameGlossary entry 3700

BIS-HYDROXYETHYL TROMETHAMINE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
2

Resolved substance identity

CAS:6976-37-0
EC:230-237-7
Ingredient index records:
BIS-HYDROXYETHYL TROMETHAMINE
Cosmetic functions: BUFFERING

2-[bis(2-Hydroxyethyl)amino]-2-hydroxymethyl-1,3-propanediol

1 matched or reported name
BIS-HYDROXYETHYL TROMETHAMINE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name BIS-HYDROXYETHYL TROMETHAMINE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

Chemical identity and properties

PubChem 2D chemical structure for CAS 6976-37-0
CAS 6976-37-0PubChem CID 81462

Bistris

Bis-tris is a buffer substance useful for calibration of glass electrodes and for the preparation of the biochemical and biological buffer solutions; pKa = 6.46 at 25 C. It has a role as a buffer. It is functionally related to a member of tris. — ChEBI

IUPAC name
2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol
Molecular formula
C8H19NO5
Molecular weight
209.24 g/mol
Exact mass
209.12632271 Da
XLogP3
-3.3
Topological polar surface area
104.0 Ų
Hydrogen-bond donors
5
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
0

Also known as

bis-tris2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol2-(Bis(2-hydroxyethyl)amino)-2-(hydroxymethyl)propane-1,3-diolQ1XC3631CPCHEBI:412501,3-Propanediol, 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-NSC-24868NSC-119932
16 more reported names
1,3-Propanediol, 2-(bis(2-hydroxyethyl)amino)-2-(hydroxymethyl)-2,2-Bis[hydroxymethyl]-2,2',2''-nitrilotriethanolRefChem:569580bis(2-hydroxyethyl)imino-tris(hydroxymethyl)methane2-(bis(2-hydroxyethyl)amino)-2(hydroxymethyl)-1,3-propanediol2,2-BIS(HYDROXYETHYL)-(IMINOTRIS)-(HYDROXYMETHYL)METHANE230-237-7686-880-2Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methaneBIS-TRIS BUFFERBis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2,2-Bis(hydroxymethyl)-2,2,2-nitrilotriethanol2-(Bis(2-hydroxyethyl)amino))-2-hydroxymethyl-1,3-propanediolBis-(2-hydroxyethyl)aminotris(hydroxymethyl)methaneBistris; NSC 119932; NSC 24868; NuPage Bis-Tris
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

Open official Decision