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EU cosmetic ingredients, restrictions and safety
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Official EU label nameGlossary entry 331

4-HYDROXYBENZOIC ACID

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 4 of 13 indexed market datasets: 4 country records and 0 EU Annex records. Every result and evidence gap is listed below.

4 markets with evidence
Markets checked
13
Markets with evidence
4
Evidence gaps
9
Resolved identifiers
20

A missing local match is not permission, approval or proof of safety. It means no strong identity match was resolved in that indexed dataset.

Resolved substance identity

CAS:99-96-799-76-336457-19-916782-08-45026-62-035285-68-8120-47-8114-63-626112-07-269959-44-0
EC:202-804-9202-785-7253-048-1240-830-2225-714-1252-487-6204-399-4204-051-1247-464-2274-235-4
Ingredient index records:
4-HYDROXYBENZOIC ACID
Cosmetic functions: FRAGRANCE, PRESERVATIVE

4-hydroxybenzoic acid

Inventory restriction note: V/12

Open full local profile
5 matched or reported names
4-HYDROXYBENZOIC ACID4-Hydroxybenzoic acidmethylparabenpotassium ethylparabenpotassium parabensodium methylparabensodium ethylparabenethylparabensodium parabenpotassium methylparabencalcium paraben4-Hydroxybenzoic acid and its methyl- and ethyl-esters, and their salts e.g. 4-hydroxybenzoic acid4-Hydroxybenzoic acid and its Methyl- and Ethyl- esters, and their salts (INCI) 4-Hydroxybenzoic acid; CAS No. 99-96-7; Methylparaben; CAS No. 99-76-3; potassium ethylparaben; CAS No. 36457-19-9; potassium paraben; CAS No. 16782-08-4 sodium methylparaben; CAS No. 5026-62-0; sodium ethylparaben; CAS No. 35285-68-8; ethylparaben; CAS No. 120-47-8; sodium paraben; CAS No. 114-63-6; potassium methylparaben; CAS No. 26112-07- 2; calcium paraben; CAS No. 69959-44-0;p-하이드록시벤조익애씨드, 그 염류 및에스텔류 (다만, 에스텔류 중 페닐은제외)

Regulatory evidence in all 13 markets

Open each matched record for its scope, concentration, conditions, warnings and official source version.

Swipe or scroll horizontally to see dataset coverage and next actions.

MarketResultRecordsDatasetMeaning / next action
European Union
EU
No local match0
Complete annex dataset
Regulation (EC) 1223/2009 consolidated to 1 May 2026
No annex match only means that these five annexes did not return a match; CosIng identity data and other EU obligations still need review.
Great Britain
GB
Permitted list with conditions1Open record 1
Complete consolidated annex dataset
GB retained Regulation 1223/2009 schedules, effective 15 August 2026
Review every linked record and exact conditions.
Canada
CA
No local match0
Complete Hotlist snapshot
Health Canada Cosmetic Ingredient Hotlist, 13 August 2025
The Hotlist is an administrative compliance tool, not an exhaustive safety approval list.
New Zealand
NZ
Permitted list with conditions1Open record 1
Complete schedules dataset
Cosmetic Products Group Standard schedules effective 1 January 2026
Review every linked record and exact conditions.
ASEAN
ASEAN
Permitted list with conditions1Open record 1
Complete regional annex dataset
ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026
Review every linked record and exact conditions.
China
CN
No local match0
Complete prohibited catalogues plus official-source workflow
NMPA 2021 banned catalogues plus dynamic IECIC List I/List II system current since 2025
IECIC listing is not blanket approval; absence may require the new cosmetic ingredient route, and restrictions are checked separately.
Japan
JP
No local match0
Complete Standards appendices dataset
MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshot
The Japanese text and subsequent notices are canonical; no local match is not a product-compliance conclusion.
South Korea
KR
Restricted1Open record 1
Complete current appendix dataset
MFDS Notice 2026-19, effective 18 March 2026
Review every linked record and exact conditions.
United States
US
No local match0
Complete enumerated federal ingredient rules
eCFR Title 21 issue date 27 August 2026
FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety.
Australia
AU
No local match0
Complete cosmetic-relevant Poisons Standard subset plus official workflow
Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026
An AICIS Inventory match is not cosmetic approval; no Inventory match can indicate a new, exempted, reported or confidential introduction.
Brazil
BR
No local match0
Complete prohibited dataset plus current restricted-list workflow
ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026
RDC 1.030/2026 amends rather than replaces the prohibited baseline, and the second restricted-list revision was still under consultation in July 2026.
India
IN
No local match0
Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4
Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022)
The standards are separate controlled publications; absence from a locally indexed excerpt is not permission.
Saudi Arabia
SA
No local match0
Complete official list index
SFDA live prohibited/restricted lists, snapshot 30 August 2026
No list match is not permission; Gulf/SFDA product, claim, notification and technical requirements still apply.
No market rows match this filter.

Matching market records and conditions

ASEAN

ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026
4-Hydroxybenzoic acid and its Methyl- and Ethyl- esters, and their salts (INCI) 4-Hydroxybenzoic acid; CAS No. 99-96-7; Methylparaben; CAS No. 99-76-3; potassium ethylparaben; CAS No. 36457-19-9; potassium paraben; CAS No. 16782-08-4 sodium methylparaben; CAS No. 5026-62-0; sodium ethylparaben; CAS No. 35285-68-8; ethylparaben; CAS No. 120-47-8; sodium paraben; CAS No. 114-63-6; potassium methylparaben; CAS No. 26112-07- 2; calcium paraben; CAS No. 69959-44-0;Permitted list with conditions
0.4% (as acid) for single ester 0.8% (as acid) for mixtures of esters
ASEAN Annex VI, reference 12 · 2026-1

Chemical identity and properties

PubChem 2D chemical structure for CAS 114-63-6
CAS 114-63-6PubChem CID 16219477

Sodium 4-hydroxybenzoate

IUPAC name
sodium 4-hydroxybenzoate
Molecular formula
C7H5NaO3
Molecular weight
160.10 g/mol
Exact mass
160.01363830 Da
Topological polar surface area
60.4 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Covalent units
2
Defined stereocentres
0

Also known as

Sodium p-hydroxybenzoate4-Hydroxybenzoic acid sodium saltsodium parabenp-Hydroxybenzoic acid sodium saltBenzoic acid, 4-hydroxy-, monosodium saltMonosodium p-hydroxybenzoateMonosodium 4-hydroxybenzoateBenzoic acid, 4-hydroxy-, sodium salt (1:1)
16 more reported names
EINECS 204-051-1p-hydroxybenzoic acid monosodium saltV6102T509BBENZOIC ACID, p-HYDROXY-, SODIUM SALTCHEBI:113449SODIUM 4-HYDROXYBENZOIC ACIDBENZOIC ACID, P-HYDROXY-, MONOSODIUM SALTRefChem:887100SODIUM PARABEN [INCI]sodium;4-hydroxybenzoateC7H5NaO3H0221UNII-V6102T509B4-Hydroxybenzoate sodiumsodium parahydroxybenzoate4-Hydroxybenzoic acid sodium
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match16219477

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 3.5% (3 of 86) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H315 (96.5%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (96.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (95.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 86 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 3 of 86 reports by companies.; There are 5 notifications provided by 83 of 86 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Cosmetic Ingredient Review Conclusion: The CIR Expert Panel concluded that the following 20 parabens are safe in cosmetics in the present practices of use and concentration described in the safety assessment when the sum of the combined concentration of parabens in any given formulation does not exceed 0.8 %...Sodium Paraben... Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 120-47-8
CAS 120-47-8PubChem CID 8434

Ethylparaben

IUPAC name
ethyl 4-hydroxybenzoate
Molecular formula
C9H10O3
Molecular weight
166.17 g/mol
Exact mass
166.062994177 Da
XLogP3
2.5
Topological polar surface area
46.5 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

Ethyl parabenEthyl p-hydroxybenzoateTegosept EMycoctenEthyl parasept4-Hydroxybenzoic acid ethyl esterAseptoform ENipagin A
16 more reported names
EaseptolEthyl butexNapagin ANipazin ASolbrol ASobrol AEthyl parahydroxybenzoatep-Hydroxybenzoic acid ethyl esterEthyl p-oxybenzoateBonomold OEBenzoic acid, 4-hydroxy-, ethyl esterp-CarbethoxyphenolEthyl-p-hydroxybenzoateMekkings EAseptin AEthyl hydroxybenzoate
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match8434

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 60.7% (811 of 1336) of all reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H304 (33.5%): May be fatal if swallowed and enters airways [Danger Aspiration hazard]; H315 (38.8%): Causes skin irritation [Warning Skin corrosion/irritation]; H317 (34%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H319 (39.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P264+P265, P272, P280, P301+P316, P302+P352, P305+P351+P338, P321, P331, P332+P317, P333+P317, P337+P317, P362+P364, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 1336 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 811 of 1336 reports by companies.; There are 8 notifications provided by 525 of 1336 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Note: This chemical does not meet GHS hazard criteria for 100% (2 of 2) of all reports. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 2 of 2 companies. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 2 reports by companies from 1 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 2 of 2 reports by companies.; There are 0 notifications provided by 0 of 2 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H401: Toxic to aquatic life [Hazardous to the aquatic environment, acute hazard] Source: Hazardous Substances Data Bank (HSDB)
  • Precautionary Statement Codes: P273, and P501 (click each P-code to see the statement) Source: Hazardous Substances Data Bank (HSDB)
  • Cosmetic Ingredient Review Conclusion: The CIR Expert Panel concluded that the following 20 parabens are safe in cosmetics in the present practices of use and concentration described in the safety assessment when the sum of the combined concentration of parabens in any given formulation does not exceed 0.8 %...Ehtylparaben.. Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)
  • Toxicity Summary: IDENTIFICATION AND USE: Ethylparaben forms small colorless crystals, or white powder. Ethylparaben inhibits the growth of fungi and bacteria and is used as a preservative for pharmaceuticals, adhesives, and various cosmetic preparations. HUMAN EXPOSURE AND TOXICITY: Ethylparaben was a skin irritant in man. It gave no evidence of sensitizing potential in a human study. The paraben esters as a generic class are rare sensitizers when applied to the intact skin of man. Application to the damaged skin is a more common cause of sensitization. A methyl:ethyl:propylparaben mixture has been shown on oral administration to exacerbate pre-existing skin complaints. ANIMAL STUDIES: Ethylparaben was an eye irritant in rabbits. A low acute oral toxicity has been demonstrated for ethylparaben in laboratory animals. Limited long-term studies in rats have also indicated a low toxicity and have generated no evidence of carcinogenic activity. Ethylparaben in the diet produced cell proliferation in the forestomach of rats. No evidence of mutagenicity was reported in limited Ames Bacterial tests. Ethylparaben did increase chromosomal aberrations in a Chinese Hamster ovary cell assay, but similar effects Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Bioconcentration: An estimated BCF of 20 was calculated for ethylparaben(SRC), using a log Kow of 2.47(1) and a regression derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), Koc values ranging from 119 to 209(2) indicate that ethylparaben is expected to have high to moderate mobility in soil(SRC). The pKa of ethylparaben is 8.34(3), indicating that this compound will partially exist in the anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(4). Volatilization of ethylparaben from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 4.8X10-9 atm-cu m/mole(SRC), using a fragment constant estimation method(5). Ethylparaben is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 9.3X10-5 mm Hg(SRC), determined from a fragment constant method(6). Half-lives of about 14 days and 3.5 days were measured in aerobic screening tests conducted with phenol- and cresol-acclimated sludge over 7 day and 1 day incubation periods(7,8), respectively, suggesting that biodegradation may be an important fate process in soil(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), Koc values ranging from 119 to 209(2), indicate that ethylparaben is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 4.8X10-9 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). According to a classification scheme(5), an estimated BCF of 20(SRC), from its log Kow of 2.47(6) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Half-lives of about 14 days and 3.5 days were measured in aerobic screening tests conducted with phenol- and cresol-acclimated sludge over 7 day and 1 day incubation periods(8,9), respectively, suggesting that biodegradation may be an important fate process in water(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), ethylparaben, which has an estimated vapor pressure of 9.3X10-5 mm Hg at 25 °C(SRC), determined from a fragment constant method(2), will exist in both the vapor and particulate phases in the ambient atmosphere. Vapor-phase ethylparaben is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be one day(SRC), calculated from its rate constant of 1.3X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Particulate-phase ethylparaben may be removed from the air by wet and dry deposition(SRC). Ethylparaben contains chromophores that absorb at wavelengths >290 nm(4) and therefore may be susceptible to direct photolysis by sunlight(SRC). Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 16782-08-4
CAS 16782-08-4PubChem CID 23672310

Potassium Paraben

IUPAC name
potassium 4-hydroxybenzoate
Molecular formula
C7H5KO3
Molecular weight
176.21 g/mol
Exact mass
175.98757550 Da
Topological polar surface area
60.4 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Covalent units
2
Defined stereocentres
0

Also known as

potassium p-hydroxybenzoateUNII-UHZ6Y0A8VRUHZ6Y0A8VREINECS 240-830-2MONOPOTASSIUM P-HYDROXYBENZOATE4-HYDROXYBENZOIC ACID POTASSIUM SALTP-HYDROXYBENZOIC ACID MONOPOTASSIUM SALTBENZOIC ACID, 4-HYDROXY-, MONOPOTASSIUM SALT
10 more reported names
BENZOIC ACID, P-HYDROXY-, MONOPOTASSIUM SALTBENZOIC ACID, 4-HYDROXY-, POTASSIUM SALT (1:1)RefChem:175568POTASSIUM PARABEN [INCI]potassium;4-hydroxybenzoatep-hydroxybenzoic acid potassium saltP-HYDROXYBENZOICACIDPOTASSIUMSALTpotassium parahydroxybenzoateMSK2535KSafinamide Impurity 45 Potassium Salt
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 26112-07-2
CAS 26112-07-2PubChem CID 23663677

Potassium Methylparaben

IUPAC name
potassium 4-methoxycarbonylphenolate
Molecular formula
C8H7KO3
Molecular weight
190.24 g/mol
Exact mass
190.00322557 Da
Topological polar surface area
49.4 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
3
Covalent units
2
Defined stereocentres
0

Also known as

UNII-M64U971IB0M64U971IB0EINECS 247-464-2Methylparaben, potassium saltBenzoic acid, 4-hydroxy-, methyl ester, potassium salt4-Hydroxybenzoic acid, methyl ester, potassium saltMETHYL P-HYDROXYBENZOATE POTASSIUM SALTMETHYL 4-HYDROXYBENZOATE POTASSIUM SALT
12 more reported names
BENZOIC ACID, P-HYDROXY-, METHYL ESTER, POTASSIUM SALTBENZOIC ACID, 4-HYDROXY-, METHYL ESTER, POTASSIUM SALT (1:1)RefChem:175524POTASSIUM METHYLPARABEN [INCI]247-464-2Potassium methyl 4-oxidobenzoatepotassium;4-methoxycarbonylphenolateMETHYL 4-HYDROXYBENZOATE POTASSIUMpotassium 4-(methoxycarbonyl)phenolateMETHYL4-HYDROXYBENZOATEPOTASSIUMMSK2509KMOCBTMXJPWSHOD-UHFFFAOYSA-M
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 35285-68-8
CAS 35285-68-8PubChem CID 52913806

SODIUM ETHYL p-HYDROXYBENZOATE

Molecular formula
C9H10NaO3
Molecular weight
189.16 g/mol
Exact mass
189.05276346 Da
Topological polar surface area
46.5 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Covalent units
2
Defined stereocentres
0

Also known as

RefChem:1098791Benzoic acid, 4-hydroxy-, ethyl ester, sodium saltp-Hydroxybenzoic acid ethyl ester sodium saltSodium Ethyl Parabenp-Hydroxybenzoic acid ethyl ester sodium salt;Sodium 2-ethyl-4-hydroxybenzoate
Open full PubChem recordPubChem annotations3D structure image

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 36457-19-9
CAS 36457-19-9PubChem CID 23696798

Potassium Ethylparaben

IUPAC name
potassium 4-ethoxycarbonylphenolate
Molecular formula
C9H9KO3
Molecular weight
204.26 g/mol
Exact mass
204.01887563 Da
Topological polar surface area
49.4 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
3
Covalent units
2
Defined stereocentres
0

Also known as

ethylparaben potassiumUNII-528JBB2994EINECS 253-048-1528JBB2994ETHYL P-HYDROXYBENZOATE POTASSIUM SALTP-HYDROXYBENZOIC ACID ETHYL ESTER POTASSIUM SALTRefChem:175473POTASSIUM ETHYLPARABEN [INCI]
9 more reported names
BENZOIC ACID, 4-HYDROXY-, ETHYL ESTER, POTASSIUM SALT (1:1)Potassium ethyl 4-oxidobenzoatepotassium;4-ethoxycarbonylphenolateBenzoic acid, 4-hydroxy-, ethyl ester, potassium saltMSK2510KHFTYFFXNUVBSII-UHFFFAOYSA-MPotassium 4-(ethoxycarbonyl)phenolateETHYL 4-HYDROXYBENZOATE POTASSIUM SALTPotassium Ethyl-p-hydroxyl Benzoate Solution, 100pm
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 5026-62-0
CAS 5026-62-0PubChem CID 23663626

Methylparaben Sodium

IUPAC name
sodium 4-methoxycarbonylphenolate
Molecular formula
C8H7NaO3
Molecular weight
174.13 g/mol
Exact mass
174.02928836 Da
Topological polar surface area
49.4 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
3
Covalent units
2
Defined stereocentres
0

Also known as

Paratexin msParidol mnaNipagin m sodiumsodium methyl parabenSolbrol m sodium saltCR6K9C2NHKMethylparaben, sodium saltNs 3500s
16 more reported names
RefChem:158282225-714-1Sodium 4-(methoxycarbonyl)phenolateSodium methylparabenMethyl 4-hydroxybenzoate, sodium saltMethyl 4-hydroxybenzoate sodium saltSodium 4-carbomethoxyphenolateSodium methyl p-hydroxybenzoateMethylparaben sodium saltsodium;4-methoxycarbonylphenolateUNII-CR6K9C2NHKSodium Methyl ParahydroxybenzoateSodium methylparaben, 99%4-Hydroxybenzoic acid-methyl ester sodiumPreserval MSSolparol
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 69959-44-0
CAS 69959-44-0PubChem CID 54686127

Calcium bis(4-hydroxybenzoate)

IUPAC name
calcium bis(4-carboxyphenolate)
Molecular formula
C14H10CaO6
Molecular weight
314.30 g/mol
Exact mass
314.0103289 Da
Topological polar surface area
121.0 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
6
Covalent units
3
Defined stereocentres
0

Also known as

EINECS 274-235-4RefChem:122778274-235-4calcium;4-carboxyphenolateMSK2535CaCalcium Bis(4-Hydroxybenzoate) Solution, 100pm
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 99-76-3
CAS 99-76-3PubChem CID 7456

Methylparaben

Methylparaben is a 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol. It is the most frequently used antimicrobial preservative in cosmetics. It occurs naturally in several fruits, particularly in blueberries. It has a role as an antifungal agent, a neuroprotective agent, an antimicrobial food preservative and a plant metabolite. — ChEBI

IUPAC name
methyl 4-hydroxybenzoate
Molecular formula
C8H8O3
Molecular weight
152.15 g/mol
Exact mass
152.047344113 Da
XLogP3
2.0
Topological polar surface area
46.5 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

Methyl parabenMethyl p-hydroxybenzoateNipaginTegosept MMoldexMaseptolMethyl parahydroxybenzoatep-Hydroxybenzoic acid methyl ester
16 more reported names
Preserval MPreservalMetabenMethabenMetoxydeParidolSolbrolSeptosMethyl parasept4-Hydroxybenzoic acid methyl esterMethyl butexMethyl chemoseptp-Methoxycarbonylphenolp-CarbomethoxyphenolNipagin MBenzoic acid, 4-hydroxy-, methyl ester
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External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 99-96-7
CAS 99-96-7PubChem CID 135

4-Hydroxybenzoic Acid

4-hydroxybenzoic acid is a monohydroxybenzoic acid that is benzoic acid carrying a hydroxy substituent at C-4 of the benzene ring. It has a role as a plant metabolite and an algal metabolite. It is a conjugate acid of a 4-hydroxybenzoate. — ChEBI

IUPAC name
4-hydroxybenzoic acid
Molecular formula
C7H6O3
Molecular weight
138.12 g/mol
Exact mass
138.031694049 Da
XLogP3
1.6
Topological polar surface area
57.5 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

p-Hydroxybenzoic acidp-Salicylic acid4-CarboxyphenolBenzoic acid, 4-hydroxy-Benzoic acid, p-hydroxy-para-Hydroxybenzoic acidp-OxybenzoesaureJG8Z55Y12H
16 more reported names
NSC-4961FEMA NO. 3986CHEBI:30763CHEBI:17879RefChem:25955202-804-94-Hydroxybenzoatep-carboxyphenol4-hydroxy benzoic acidHydroxybenzoic acid4-HydroxybenzoesaeureParaben-acidp-Oxybenzoesaure [German]p-hydroxy benzoic acid4-hydroxy-benzoic acidAcido p-idrossibenzoico [Italian]
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Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

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