Official EU label nameGlossary entry 3293

BERGENIN

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:477-90-7

Ingredient index records:

BERGENIN

Cosmetic functions: SKIN CONDITIONING

3,4,4a,10b-Tetrahydro-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxypyrano(3,2-c)(2)benzopyran-6(H)-one

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2 matched or reported names

BERGENINBergenin [JAN]

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name BERGENIN.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 477-90-7

CAS 477-90-7PubChem CID 66065

Bergenin

Bergenin is a natural product found in Cenostigma gardnerianum. It has a role as a metabolite. — ChEBI

IUPAC name: (2R,3S,4S,4aR,10bS)-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one

Molecular formula: C14H16O9
Molecular weight: 328.27 g/mol
Exact mass: 328.07943208 Da
XLogP3: -1.0
Topological polar surface area: 146.0 Å²
Hydrogen-bond donors: 5
Hydrogen-bond acceptors: 9
Covalent units: 1
Defined stereocentres: 5

Also known as

YanbaicaisuBergeninumL84RBE4IDCNSC-661749NSC-7577964-Methoxy-2-(tetrahydro-3,4,5-trihydroxy-6-(hydroxymethyl)pyran-2-yl)alpha-resorcylic acid gamma lactone(2R,3S,4S,4aR,10bS)-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydro-2H-pyrano(3,2-c)isochromen-6-one(-)-Bergenin

16 more reported names

RefChem:567029GlyTouCan:G67862GT803-760-9BengeninCuscutinBergenin [JAN]CorylopsinCHEBI:69499Bergenin (JAN)CCG-208553(2R,3S,4S,4aR,10bS)-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydropyrano[3,2-c]isochromen-6(2H)-onePyrano[3,2-c][2]benzopyran-6(2H)-one,3,4,4a,10b-tetrahydro-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-, (2R,3S,4S,4aR,10bS)-C14H16O9B4349EN300-19651064(2R,3S,4S,4aR,10bS)-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-2,3,4,4a-tetrahydropyrano[3,2-c]isochromen-6(10bH)-one

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External database identifiers

ChEBI:CHEBI:69499
ChEMBL:CHEMBL273019
EPA DTXSID:DTXSID4048141
PubMed:23054709
PubMed:22593249
PubMed:22574013
PubMed:22557239
PubMed:22437110
PubMed:22389182
PubMed:22275971
PubMed:22272145
PubMed:22253106
PubMed:22224047
PubMed:22206469
PubMed:22178680

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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