Official EU label nameGlossary entry 29794

VALINE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence

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Evidence gaps

Resolved identifiers

Resolved substance identity

CAS:516-06-3640-68-672-18-4

EC:208-220-0211-368-9200-773-6

Ingredient index records:

VALINE

Ph. Eur. name: valinum

Cosmetic functions: ANTISTATIC, FRAGRANCE, HAIR CONDITIONING, SKIN CONDITIONING

2-Amino-3-methylbutanoic acid

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3 matched or reported names

VALINEvalinevalinum

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name VALINE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 516-06-3

CAS 516-06-3PubChem CID 1182

DL-valine

Valine is a branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isopropyl group. It has a role as a plant metabolite and a Daphnia magna metabolite. It is a branched-chain amino acid and an alpha-amino acid. It contains an isopropyl group. It is a conjugate base of a valinium. It is a conjugate acid of a valinate. — ChEBI

IUPAC name: 2-amino-3-methylbutanoic acid

Molecular formula: C5H11NO2
Molecular weight: 117.15 g/mol
Exact mass: 117.078978594 Da
XLogP3: -2.3
Topological polar surface area: 63.3 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

Valine, DL-FEMA No. 3444D,L-VALINENSC 9755CCRIS 86044CA13A832HNSC-9755EINECS 208-220-0

16 more reported names

D,L-VALINE [FHFI]AI3-18308Valine, DLRefChem:5899872Aminoisovaleric acid, DLalphaAminoisovaleric acid, DL2Amino3methylbutyric acid, DL2Amino3methylbutanoic acid, DL208-220-02-Amino-3-methylbutanoic acid (VAN)H-DL-Val-OH2-Amino-3-methylbutanoic acid, DL-DL-.alpha.-Aminoisovaleric acidHY-W012889(+/-)-2-AMINOISOVALERIC ACIDAS-11670

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External database identifiers

ChEBI:CHEBI:27266
ChEMBL:CHEMBL11257
EPA DTXSID:DTXSID70859522
PubMed:22441188
PubMed:22408663
PubMed:22393298
PubMed:22369691
PubMed:22331998
PubMed:22327513
PubMed:22306479
PubMed:22216094
PubMed:22199582
PubMed:22137999
PubMed:22065415
PubMed:22048449

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 640-68-6

CAS 640-68-6PubChem CID 71563

D-Valine

D-valine is the D-enantiomer of valine. It is a D-alpha-amino acid and a valine. It is a conjugate base of a D-valinium. It is a conjugate acid of a D-valinate. It is an enantiomer of a L-valine. It is a tautomer of a D-valine zwitterion. — ChEBI

IUPAC name: (2R)-2-amino-3-methylbutanoic acid

Molecular formula: C5H11NO2
Molecular weight: 117.15 g/mol
Exact mass: 117.078978594 Da
XLogP3: -2.3
Topological polar surface area: 63.3 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 1

Also known as

(R)-ValineValine, D-D-valin(R)-2-Amino-3-methylbutyric acidEINECS 211-368-9NSC 20654D-2-Amino-3-methylbutanoic acidD-(-)-VALINE

16 more reported names

Y14I1443URNSC-20654VALINE, (-)-CHEBI:27477D-2-amino-3-methylbutyric acid2-Amino-3-methylbutanoic acid(D)(R)ValineRefChem:585124D2Amino3methylbutanoic acid(R)alphaAminoisovaleric acid(2R)-2-azaniumyl-3-methylbutanoate211-368-9InChI=1/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m1/sH-D-Val-OH(R)-2-Amino-3-methylbutanoic acidR-Valine

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External database identifiers

ChEBI:CHEBI:27477
ChEMBL:CHEMBL1232398
EPA DTXSID:DTXSID0046064
PubMed:21919488
PubMed:19760730
PubMed:5810

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 72-18-4

CAS 72-18-4PubChem CID 6287

L-Valine

L-valine is the L-enantiomer of valine. It has a role as a micronutrient, a nutraceutical, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a human metabolite and an algal metabolite. It is a L-alpha-amino acid, a pyruvate family amino acid, a valine and a proteinogenic amino acid. It is a conjugate base of a L-valinium. It is a conjugate acid of a L-valinate. It is an enantiomer of a D-valine. It is a tautomer of a L-valine zwitterion. — ChEBI

IUPAC name: (2S)-2-amino-3-methylbutanoic acid

Molecular formula: C5H11NO2
Molecular weight: 117.15 g/mol
Exact mass: 117.078978594 Da
XLogP3: -2.3
Topological polar surface area: 63.3 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 1

Also known as

valine(S)-Valine(S)-2-Amino-3-methylbutanoic acid2-Amino-3-methylbutyric acid(S)-2-Amino-3-methylbutyric acidvalinaL-alpha-Amino-beta-methylbutyric acidL-valin

16 more reported names

Valinum(S)-alpha-Amino-beta-methylbutyric acidNSC-76038l-(+)-alpha-Aminoisovaleric acidHG18B9YRS7CHEBI:16414L-Val2-amino-3-methylbutanoate(2S)-2-amino-3-methylbutanoatel valineCHEBI:27266L-Valine HighRefChem:6509L-Valine 7429L-Valine High 7430(2S)-2-amino-3-methylbutanoate;hydron

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External database identifiers

ChEBI:CHEBI:16414
ChEMBL:CHEMBL43068
EPA DTXSID:DTXSID40883233
PubMed:40885242
PubMed:39172838
PubMed:29968805
PubMed:23124343
PubMed:23108620
PubMed:23107499
PubMed:23105881
PubMed:23088461
PubMed:23087757
PubMed:23084640
PubMed:23079773
PubMed:23077896

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

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Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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