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Official EU label nameGlossary entry 29456

TRISILOXANE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
2

Resolved substance identity

CAS:107-51-7
EC:203-497-4
Ingredient index records:
TRISILOXANE
Cosmetic functions: ANTIFOAMING, SKIN CONDITIONING

Trisiloxane, Octamethyl-

1 matched or reported name
TRISILOXANE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name TRISILOXANE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

Chemical identity and properties

PubChem 2D chemical structure for CAS 107-51-7
CAS 107-51-7PubChem CID 24705

Octamethyltrisiloxane

Octamethyltrisiloxane is an organosiloxane that is trisiloxane in which all the hydrogens have been replaced by methyl groups. — ChEBI

IUPAC name
dimethyl-bis(trimethylsilyloxy)silane
Molecular formula
C8H24O2Si3
Molecular weight
236.53 g/mol
Exact mass
236.10840961 Da
Topological polar surface area
18.5 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

Trisiloxane, octamethyl-1,1,1,3,3,5,5,5-OctamethyltrisiloxanePentamethyl(trimethylsilyloxy)disiloxaneDimethylbis(trimethylsiloxy)silane9G1ZW13R0GPentamethyl(trimethylsiloxy)disiloxaneCHEBI:9147RefChem:1093790
16 more reported names
203-497-4Dimethicone 350Simethicone Impurity 6Silicone oil PMX-200Trisiloxane, 1,1,1,3,3,5,5,5-octamethyl-CCRIS 3198EINECS 203-497-4UNII-9G1ZW13R0GC8H24O2Si3Dimeticone CRSMethylsilicone oiloctamethyl-trisiloxaneDimethylsilicone oil,Hexamethyloxy disilanedimethicone macromoleculeEC 203-497-4
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:9147

octamethyltrisiloxane

An organosiloxane that is trisiloxane in which all the hydrogens have been replaced by methyl groups.

Formula
C8H24O2Si3
Average mass
236.536 g/mol
Monoisotopic mass
236.10841 Da
Formal charge
0
  • organosiloxane — is a (CHEBI:48150)
  • organosiloxane — is a (CHEBI:48150)
Additional curated names
octamethyltrisiloxane1,1,1,3,3,5,5,5-octamethyltrisiloxanedimethylbis(trimethylsiloxy)siliane
Cross-references from this source
  • CAS: 107-51-7 — ChemIDplus
  • CAS: 107-51-7 — NIST Chemistry WebBook
  • REGISTRY_NUMBER: 1753063 — Reaxys
  • MANUAL_X_REF: C07261 — KEGG COMPOUND

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2019-11-04. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match24705

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 11.1% (49 of 443) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H226 (88.9%): Flammable liquid and vapor [Warning Flammable liquids]; H413 (27.1%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P273, P280, P303+P361+P353, P370+P378, P403+P235, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 443 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 49 of 443 reports by companies.; There are 5 notifications provided by 394 of 443 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Sources/Uses: Used as a base for extreme temperature silicone oils/fluids and as a foam suppressant in petroleum lubricating oils; [Merck Index] Used mainly to make polydimethylsiloxane (PDMS) polymers, oligomers, and mixtures; Also used to make basic chemicals, paints, coatings, adhesives, soaps, cleaning compounds, toiletries, plastics, semiconductors, and other electronic components, and in building construction, lubricants, diluents, solvents, and cosmetics; [Government of Canada - Chemicals Management Plan] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Semiconductor Manufacturing [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

Open official Decision