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InventoryRef 5988515/10/2010

TRISILOXANE

Trisiloxane, Octamethyl-

TRISILOXANE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 107-51-7
CAS 107-51-7PubChem CID 24705

Octamethyltrisiloxane

Octamethyltrisiloxane is an organosiloxane that is trisiloxane in which all the hydrogens have been replaced by methyl groups. ChEBI

IUPAC name
dimethyl-bis(trimethylsilyloxy)silane
Molecular formula
C8H24O2Si3
Molecular weight
236.53 g/mol
Exact mass
236.10840961 Da
Topological polar surface area
18.5 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Covalent units
1
Defined stereocentres
0

Also known as

Trisiloxane, octamethyl-1,1,1,3,3,5,5,5-OctamethyltrisiloxanePentamethyl(trimethylsilyloxy)disiloxaneDimethylbis(trimethylsiloxy)silane9G1ZW13R0GPentamethyl(trimethylsiloxy)disiloxaneCHEBI:9147RefChem:1093790
16 more reported names
203-497-4Dimethicone 350Simethicone Impurity 6Silicone oil PMX-200Trisiloxane, 1,1,1,3,3,5,5,5-octamethyl-CCRIS 3198EINECS 203-497-4UNII-9G1ZW13R0GC8H24O2Si3Dimeticone CRSMethylsilicone oiloctamethyl-trisiloxaneDimethylsilicone oil,Hexamethyloxy disilanedimethicone macromoleculeEC 203-497-4
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:9147

octamethyltrisiloxane

An organosiloxane that is trisiloxane in which all the hydrogens have been replaced by methyl groups.

Formula
C8H24O2Si3
Average mass
236.536 g/mol
Monoisotopic mass
236.10841 Da
Formal charge
0
  • organosiloxane — is a (CHEBI:48150)
  • organosiloxane — is a (CHEBI:48150)
Additional curated names
octamethyltrisiloxane1,1,1,3,3,5,5,5-octamethyltrisiloxanedimethylbis(trimethylsiloxy)siliane
Cross-references from this source
  • CAS: 107-51-7 — ChemIDplus
  • CAS: 107-51-7 — NIST Chemistry WebBook
  • REGISTRY_NUMBER: 1753063 — Reaxys
  • MANUAL_X_REF: C07261 — KEGG COMPOUND

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2019-11-04. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match24705

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 11.1% (49 of 443) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H226 (88.9%): Flammable liquid and vapor [Warning Flammable liquids]; H413 (27.1%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P273, P280, P303+P361+P353, P370+P378, P403+P235, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 443 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 49 of 443 reports by companies.; There are 5 notifications provided by 394 of 443 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Sources/Uses: Used as a base for extreme temperature silicone oils/fluids and as a foam suppressant in petroleum lubricating oils; [Merck Index] Used mainly to make polydimethylsiloxane (PDMS) polymers, oligomers, and mixtures; Also used to make basic chemicals, paints, coatings, adhesives, soaps, cleaning compounds, toiletries, plastics, semiconductors, and other electronic components, and in building construction, lubricants, diluents, solvents, and cosmetics; [Government of Canada - Chemicals Management Plan] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Semiconductor Manufacturing [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for TRISILOXANE

INCI name

TRISILOXANE

Description

Trisiloxane, Octamethyl-

Record provenance

Inventory reference
59885
Imported identity
TRISILOXANE
Source update
15/10/2010
European Commission CosIng source notes

Key data

Restriction
Function
ANTIFOAMING
Suppressing foam during manufacturing or reducing the tendency of finished products to generate foam.
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How TRISILOXANE appears in the CosIng inventory

The CosIng inventory lists TRISILOXANE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TRISILOXANE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TRISILOXANE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, TRISILOXANE carries the following function designation(s):

CAS 107-51-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for TRISILOXANE

This page reproduces the CosIng inventory entry for TRISILOXANE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research TRISILOXANE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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