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Official EU label nameGlossary entry 29167

TRIETHYLENE GLYCOL

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
2

A missing local match is not permission, approval or proof of safety. It means no strong identity match was resolved in that indexed dataset.

Resolved substance identity

CAS:112-27-6
EC:203-953-2
Ingredient index records:
TRIETHYLENE GLYCOL
Cosmetic functions: FRAGRANCE, PERFUMING, VISCOSITY CONTROLLING

2,2'-(Ethylenedioxy)diethanol

Open full local profile
1 matched or reported name
TRIETHYLENE GLYCOL

Regulatory evidence in all 13 markets

Open each matched record for its scope, concentration, conditions, warnings and official source version.

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MarketResultRecordsDatasetMeaning / next action
European Union
EU
No local match0
Complete annex dataset
Regulation (EC) 1223/2009 consolidated to 1 May 2026
No annex match only means that these five annexes did not return a match; CosIng identity data and other EU obligations still need review.
Great Britain
GB
No local match0
Complete consolidated annex dataset
GB retained Regulation 1223/2009 schedules, effective 15 August 2026
No annex match is not approval and does not cover Northern Ireland, which follows the applicable EU framework.
Canada
CA
No local match0
Complete Hotlist snapshot
Health Canada Cosmetic Ingredient Hotlist, 13 August 2025
The Hotlist is an administrative compliance tool, not an exhaustive safety approval list.
New Zealand
NZ
No local match0
Complete schedules dataset
Cosmetic Products Group Standard schedules effective 1 January 2026
The searchable spreadsheet is an aid; the legal Group Standard and incorporated notices remain authoritative.
ASEAN
ASEAN
No local match0
Complete regional annex dataset
ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026
Regional annex coverage does not replace member-state implementation dates, notifications or national deviations.
China
CN
No local match0
Complete prohibited catalogues plus official-source workflow
NMPA 2021 banned catalogues plus dynamic IECIC List I/List II system current since 2025
IECIC listing is not blanket approval; absence may require the new cosmetic ingredient route, and restrictions are checked separately.
Japan
JP
No local match0
Complete Standards appendices dataset
MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshot
The Japanese text and subsequent notices are canonical; no local match is not a product-compliance conclusion.
South Korea
KR
No local match0
Complete current appendix dataset
MFDS Notice 2026-19, effective 18 March 2026
Korean source wording is canonical and other positive lists/notices may still apply to the formulation.
United States
US
No local match0
Complete enumerated federal ingredient rules
eCFR Title 21 issue date 27 August 2026
FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety.
Australia
AU
No local match0
Complete cosmetic-relevant Poisons Standard subset plus official workflow
Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026
An AICIS Inventory match is not cosmetic approval; no Inventory match can indicate a new, exempted, reported or confidential introduction.
Brazil
BR
No local match0
Complete prohibited dataset plus current restricted-list workflow
ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026
RDC 1.030/2026 amends rather than replaces the prohibited baseline, and the second restricted-list revision was still under consultation in July 2026.
India
IN
No local match0
Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4
Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022)
The standards are separate controlled publications; absence from a locally indexed excerpt is not permission.
Saudi Arabia
SA
No local match0
Complete official list index
SFDA live prohibited/restricted lists, snapshot 30 August 2026
No list match is not permission; Gulf/SFDA product, claim, notification and technical requirements still apply.
No market rows match this filter.

Chemical identity and properties

PubChem 2D chemical structure for CAS 112-27-6
CAS 112-27-6PubChem CID 8172

Triethylene Glycol

IUPAC name
2-[2-(2-hydroxyethoxy)ethoxy]ethanol
Molecular formula
C6H14O4
Molecular weight
150.17 g/mol
Exact mass
150.08920892 Da
XLogP3
-1.6
Topological polar surface area
58.9 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

Triglycol2,2'-(Ethane-1,2-diylbis(oxy))diethanol2,2'-EthylenedioxydiethanolTrigenTriethylenglykolTriethyleneglycol1,2-Bis(2-hydroxyethoxy)ethane2,2'-Ethylenedioxybis(ethanol)
16 more reported names
3,6-Dioxaoctane-1,8-diol2,2'-(Ethylenedioxy)diethanol2,2'-EthylenedioxyethanolDi-beta-hydroxyethoxyethaneGlycol bis(hydroxyethyl) etherTrigolEthanol, 2,2'-[1,2-ethanediylbis(oxy)]bis-Ethylene glycol dihydroxydiethyl ether2,2'-[ethane-1,2-diylbis(oxy)]diethanolBis(2-hydroxyethoxyethane)Ethanol, 2,2'-(ethylenedioxy)di-2,2'-(1,2-Ethanediylbis(oxy))bisethanolEthylene glycol-bis-(2-hydroxyethyl ether)Ethanol, 2,2'-(1,2-ethanediylbis(oxy))bis-NSC-607583P5SU53360
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match8172

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
  • Note: This chemical does not meet GHS hazard criteria for 97.2% (2397 of 2467) of all reports. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 2397 of 2467 companies (only 2.8% companies provided GHS information). For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 2467 reports by companies from 14 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 2397 of 2467 reports by companies.; There are 10 notifications provided by 70 of 2467 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: NITE-CMC
  • GHS Hazard Statements: H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: NITE-CMC
  • Precautionary Statement Codes: P261, P271, P304+P340, P319, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Cosmetic Ingredient Review Finding(s): Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org Source: Cosmetic Ingredient Review (CIR)
  • Toxicity Summary: Triethylene glycol (TEG) is a liquid higher glycol of very low vapor pressure with uses that are primarily industrial. It has a very low order of acute toxicity by iv, ip, peroral, percutaneous and inhalation (vapor and aerosol) routes of exposure. It does not produce primary skin iritation. Acute eye contact with the liquid causes mild local transient irritation (conjunctival hyperemia and slight chemosis) but does not induce corneal injury. Animal maximization and human volunteer repeated insult patch tests studies have shown that TEG does not cause skin sensitization. A study with Swiss-Webster mice demonstrated that TEG aerosol has properties of a peripheral chemosensory irritant material and caused a depression of breathing rate with an RD(50) of 5140 mg/ cu m. Continuous subchronic peroral dosing of TEG in the diet of rats did not produce any systemic cumulative or long-term toxicity. The effects seen were dose-related increased relative kidney weight, increased urine volume and decreased urine pH, probably a result of the renal excretion of TEG and metabolites following the absorption of large doses of TEG. There was also decreased hemoglobin concentration, decreased hematoc Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Bioconcentration: An estimated BCF of 3 was calculated in fish for triethylene glycol(SRC), using an estimated log Kow of -1.75(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 10(SRC), determined from a structure estimation method(2), indicates that triethylene glycol is expected to have very high mobility in soil(SRC). Volatilization of triethylene glycol from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 3.2X10-11 atm-cu m/mole(SRC), using a fragment constant estimation method(3). Triethylene glycol is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 1.32X10-3 mm Hg(4). A series of aerobic river die-away tests which utilized several different sources of freshwater, suggest that rapid biodegradation is likely to be the most important removal mechanism of triethylene glycol from aerobic soil(SRC); degradation was complete within 7-11 days(5). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 10(SRC), determined from a structure estimation method(2), indicates that triethylene glycol is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 3.2X10-11 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). According to a classification scheme(5), an estimated BCF of 3(SRC), from an estimated log Kow of -1.75(6) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). A series of aerobic river die-away tests, which utilized several differing sources of freshwater, suggest that rapid aerobic biodegradation is likely to be the most important removal mechanism of triethylene glycol from aquatic systems(SRC); degradation was complete within 7-11 days(8). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), triethylene glycol, which has a vapor pressure of 1.32X10-3 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase triethylene glycol is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 11 hours(SRC), calculated from its rate constant of 3.6X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Alcohols and ethers do not absorb light at wavelengths >290 nm and therefore triethylene glycol is not expected to be susceptible to direct photolysis by sunlight(4). Source: Hazardous Substances Data Bank (HSDB)
  • Consumer Uses: Humectant; Pigment; Intermediate; Not Known or Reasonably Ascertainable; Diluent; Hydraulic fluids; Plasticizer; Heat transferring agent; Processing aids not otherwise specified; Other; Lubricating agent; Solvent; Insulators Source: EPA Chemical Data Reporting (CDR)
  • Industry Uses: Humectant; Intermediate; Processing aids, specific to petroleum production; Pigment; Drier; Viscosity modifiers; Diluent; Waterproofing agent; Corrosion inhibitor; Not Known or Reasonably Ascertainable; Cleaning agent; Plasticizer; Dehydrating agent (desiccant); Absorbent; Hydraulic fluids; Heat transferring agent; pH regulating agent; Monomers; Processing aids not otherwise specified; Lubricating agent; Wetting agent (non-aqueous); Other; Solvent Source: EPA Chemical Data Reporting (CDR)
  • Cosmetic Ingredient Review Link: CIR ingredient: Triethylene Glycol Source: Cosmetic Ingredient Review (CIR)
  • Sources/Uses: Used as a fragrance (cosmetics), solvent (resins, pesticides, textile dyeing), humectant (printing inks and tobacco), plasticizer, and disinfectant; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Using Disinfectants or Biocides [Category: Clean]; Textiles (Printing, Dyeing, or Finishing) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: For triethylene glycol (USEPA/OPP Pesticide Code: 083501) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Bacteriostat (against odor-causing bacteria) for air sanitization and deodorization. In combination with other active ingredients, ... a fungicide, virucide and miticide for disinfection of hard, non-porous surfaces and as an insecticide (against lice) by direct application to caged birds and to the cage. .... As an inert ingredient, triethylene glycol facilitates delivery of formulated pesticide chemical products that are used as herbicides, fungicides, insecticides, growth regulators and attractants on a wide variety of agricultural commodities. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: EPA Pesticide Inert Group 3 (Inerts of unknown toxicity) Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Triethylene glycol is approved by the Food and Drug Administration (FDA) as a preservative for food packaging adhesives ... . Currently, however, there are no EPA registered products for this use. Triethylene glycol /is also approved as/ an indirect food additive for its use as a plasticizer in cellophane. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for TRIETHYLENE GLYCOL (12 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

These source-specific lookups can add hazard, toxicology, identity and assessment context. A link is a research route, not a claim that the source contains an exact record.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

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FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

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Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

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NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

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OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

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US EPA CompTox CTX APIs

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity

Continue the compliance check

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2. Review restrictions

Check every exact Annex record shown above, plus CMR, nanomaterial, SCCS and later-amendment requirements that may apply.

3. Verify the formula

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

Open official Decision