Official EU label nameGlossary entry 28876

TIMONACIC

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:444-27-934592-47-7

EC:207-146-6252-106-3

Ingredient index records:

TIMONACIC

Cosmetic functions: SKIN CONDITIONING

4-Thiazolidine carboxylic acid

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1 matched or reported name

TIMONACIC

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name TIMONACIC.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 34592-47-7

CAS 34592-47-7PubChem CID 93176

L-Thioproline

L-thioproline is an optically active version of thioproline having L-configuration. It has a role as a geroprotector and a metabolite. It is a thiazolidinemonocarboxylic acid and a thioproline. — ChEBI

IUPAC name: (4R)-1,3-thiazolidine-4-carboxylic acid

Molecular formula: C4H7NO2S
Molecular weight: 133.17 g/mol
Exact mass: 133.01974964 Da
XLogP3: -2.3
Topological polar surface area: 74.6 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 1

Also known as

(R)-Thiazolidine-4-carboxylic acidL-Thiaproline4-thiaproline(R)-4-Thiazolidinecarboxylic acid(4R)-4-Thiazolidinecarboxylic acidgamma-thioprolineThioproline, L-4-Thiazolidinecarboxylic acid, (4R)-

16 more reported names

(R)-(-)-4-Thiazolidinecarboxylic acid(R)-(-)-Thiazolidine-4-carboxylic Acid4-Thiazolidinecarboxylic acid, L-Timonacic, (R)-CCRIS 3646EINECS 252-106-3KL096K0KXL4-Thiazolidinecarboxylic acid, (R)-TIMONACIC, (-)-CHEBI:45171(4R)-1,3-thiazolidin-3-ium-4-carboxylateRefChem:7981322756-91-4L-4-Thiazolidinecarboxylic acidH-Thz-OH(4R)-thiazolidine-4-carboxylic acid

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External database identifiers

ChEBI:CHEBI:45171
ChEMBL:CHEMBL1235440
PubMed:21547360
PubMed:20221839

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 444-27-9

CAS 444-27-9PubChem CID 9934

Timonacic

Thioproline is a sulfur-containing amino acid that is proline in which the methylene group at position 4 is replaced by a sulfur atom. It has a role as an antioxidant, an antidote and a hepatoprotective agent. It is a sulfur-containing amino acid, a thiazolidinemonocarboxylic acid and a non-proteinogenic alpha-amino acid. It is a tautomer of a thioproline zwitterion. — ChEBI

IUPAC name: 1,3-thiazolidine-4-carboxylic acid

Molecular formula: C4H7NO2S
Molecular weight: 133.17 g/mol
Exact mass: 133.01974964 Da
XLogP3: -2.3
Topological polar surface area: 74.6 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

Thiazolidine-4-carboxylic acid4-THIAZOLIDINECARBOXYLIC ACIDDetoxepaHepalidineThioprolineThiaprolineTiazolidinNorgamem

16 more reported names

DL-Thiaproline4-CarboxythiazolidineNorgamenTimonacicoHeparegenTimonacicumNSC-25855HepacomDL-Thiazolidinecarboxylic acidAcide thiazolidine-4-carboxyliqueAcide DL thiazolidine carboxylique-4E5913T3IBLCHEBI:64564gamma-thiaprolineRefChem:8981274-thiazolidine carboxylic acid

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External database identifiers

ChEBI:CHEBI:64564
ChEMBL:CHEMBL358722
PubMed:22799571
PubMed:22645409
PubMed:22606194
PubMed:22470451
PubMed:22412715
PubMed:22412481
PubMed:22398899
PubMed:22219918
PubMed:22199796
PubMed:22199780
PubMed:22199734
PubMed:22199728

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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