Official EU label nameGlossary entry 28765

THIOHISTIDINE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence

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Evidence gaps

Resolved identifiers

Resolved substance identity

CAS:2002-22-4

EC:217-899-2

Ingredient index records:

THIOHISTIDINE

Cosmetic functions: ANTIOXIDANT, BLEACHING, CHELATING

1H-Imidazole-4-propanoic acid,α-amino-2,3-dihydro-2-thioxo; (S)-α-amino-2,3-dihydro-2-thioxo-1H-imidazole-4-propionic acid

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1 matched or reported name

THIOHISTIDINE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name THIOHISTIDINE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 2002-22-4

CAS 2002-22-4PubChem CID 2733604

(alphaS)-alpha-Amino-2,3-dihydro-2-thioxo-1H-imidazole-4-propanoic acid

IUPAC name: (2S)-2-amino-3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)propanoic acid

Molecular formula: C6H9N3O2S
Molecular weight: 187.22 g/mol
Exact mass: 187.04154771 Da
XLogP3: -3.6
Topological polar surface area: 119.0 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 1

Also known as

L-ThiolhistidineMH6EDB26P8RefChem:4057682-Mercapto-L-histidineThiohistidine(S)-2-Amino-3-(2-thioxo-2,3-dihydro-1H-imidazol-4-yl)propanoic acidL-2-MercaptohistidineH-2-MERCAPTO-HIS-OH

16 more reported names

HISTIDINE, 2-MERCAPTO-, L-(2S)-2-amino-3-(2-sulfanyl-1H-imidazol-4-yl)propanoic acid1H-Imidazole-4-propanoic acid, alpha-amino-2,3-dihydro-2-thioxo-, (alphaS)-1H-IMIDAZOLE-4-PROPANOIC ACID, .ALPHA.-AMINO-2,3-DIHYDRO-2-THIOXO-, (S)-UNII-MH6EDB26P8EINECS 217-899-2(S)-2-Mercaptohistidine(S)-alpha-Amino-2,3-dihydro-2-thioxo-1H-imidazole-4-propionic acidL-2-THIOXOHISTIDINETHIOHISTIDINE [INCI]GLXC-256442-Mercapto-L-histidine, AldrichCPR(|AS)-|A-Amino-2,3-dihydro-2-thioxo-1H-Imidazole-4-propanoic AcidEBC-64035(2S)-2-Azaniumyl-3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)propanoate2-THIOLHISTIDINE L-FORM [MI]

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External database identifiers

EPA DTXSID:DTXSID401021728

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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