Official EU label nameGlossary entry 28764

THIOGLYCOLIC ACID

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 8 of 13 indexed market datasets: 7 country records and 1 EU Annex records. Every result and evidence gap is listed below.

8 markets with evidence
Markets checked
13
Markets with evidence
8
Evidence gaps
5
Resolved identifiers
12

A missing local match is not permission, approval or proof of safety. It means no strong identity match was resolved in that indexed dataset.

Resolved substance identity

CAS:68-11-15421-46-5126-97-6814-71-1367-51-134452-51-238337-95-065208-41-529820-13-163592-16-52368928-49-6
EC:200-677-4
Ingredient index records:
THIOGLYCOLIC ACID
Cosmetic functions: ANTIOXIDANT, DEPILATORY, HAIR WAVING OR STRAIGHTENING, REDUCING

Mercaptoacetic acid

Inventory restriction note: III/2a

6 matched or reported names
THIOGLYCOLIC ACIDThioglycolic acid and its saltsThioglycolic acidThioglycolic acid and its salts CAS No 68-11-1치오글라이콜릭애씨드,그 염류 및 에스텔류Thioglycollic acid and its salts (CAS No. 68-11-1)

Regulatory evidence in all 13 markets

Open each matched record for its scope, concentration, conditions, warnings and official source version.

Swipe or scroll horizontally to see dataset coverage and next actions.

MarketResultRecordsDatasetMeaning / next action
European Union
EU
Restricted1Open record 1
Complete annex dataset
Regulation (EC) 1223/2009 consolidated to 1 May 2026
Review every linked record and exact conditions.
Great Britain
GB
Restricted1Open record 1
Complete consolidated annex dataset
GB retained Regulation 1223/2009 schedules, effective 15 August 2026
Review every linked record and exact conditions.
Canada
CA
Restricted1Open record 1
Complete Hotlist snapshot
Health Canada Cosmetic Ingredient Hotlist, 13 August 2025
Review every linked record and exact conditions.
New Zealand
NZ
Restricted1Open record 1
Complete schedules dataset
Cosmetic Products Group Standard schedules effective 1 January 2026
Review every linked record and exact conditions.
ASEAN
ASEAN
Restricted1Open record 1
Complete regional annex dataset
ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026
Review every linked record and exact conditions.
China
CN
No local match0
Complete prohibited catalogues plus official-source workflow
NMPA 2021 banned catalogues plus dynamic IECIC List I/List II system current since 2025
IECIC listing is not blanket approval; absence may require the new cosmetic ingredient route, and restrictions are checked separately.
Japan
JP
No local match0
Complete Standards appendices dataset
MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshot
The Japanese text and subsequent notices are canonical; no local match is not a product-compliance conclusion.
South Korea
KR
Restricted1Open record 1
Complete current appendix dataset
MFDS Notice 2026-19, effective 18 March 2026
Review every linked record and exact conditions.
United States
US
No local match0
Complete enumerated federal ingredient rules
eCFR Title 21 issue date 27 August 2026
FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety.
Australia
AU
No local match0
Complete cosmetic-relevant Poisons Standard subset plus official workflow
Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026
An AICIS Inventory match is not cosmetic approval; no Inventory match can indicate a new, exempted, reported or confidential introduction.
Brazil
BR
No local match0
Complete prohibited dataset plus current restricted-list workflow
ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026
RDC 1.030/2026 amends rather than replaces the prohibited baseline, and the second restricted-list revision was still under consultation in July 2026.
India
IN
Restricted1Open record 1
Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4
Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022)
Review every linked record and exact conditions.
Saudi Arabia
SA
Restricted1Open record 1
Complete official list index
SFDA live prohibited/restricted lists, snapshot 30 August 2026
Review every linked record and exact conditions.
No market rows match this filter.

Matching market records and conditions

Exact Annex II–VI evidence

THIOGLYCOLIC ACID

Product scope: (a) Hair products (b) Depilatories (c) Hair rinse-off products (d) Products intended for eyelash waving

Maximum concentration: (a) (i) 8% (ii) 11% (b) 5% (c) 2% (d) 11% The abovementioned percentages are calculated as thioglycollic acid

Restrictions: (a) (i) General use ready for use pH 7 to 9.5 (ii) Professional use ready for use pH 7 to 9.5 (b) ready for use pH 7 to 12.7 (c) ready for use pH 7 to 9.5 (d) ready for use pH 7 to 9,5

Warnings: Conditions of use: (a) (b) (c) (d) Avoid contact with eyes Rinse eyes immediately if product comes into contact with them. (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a)(i) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a)(ii) (d…

Chemical identity and properties

PubChem 2D chemical structure for CAS 126-97-6
CAS 126-97-6PubChem CID 160430

Monoethanolamine thioglycolate

IUPAC name
2-aminoethanol;2-sulfanylacetic acid
Molecular formula
C4H11NO3S
Molecular weight
153.20 g/mol
Exact mass
153.04596439 Da
Topological polar surface area
84.6 Ų
Hydrogen-bond donors
4
Hydrogen-bond acceptors
5
Covalent units
2
Defined stereocentres
0

Also known as

Ethanolamine thioglycolate(2-Hydroxyethyl)ammonium mercaptoacetateEINECS 204-815-4EC 204-815-4263SH5220TTHIOGLYCOLIC ACID MONOETHANOLAMINE SALTN-(2-HYDROXYETHYL)AMMONIUM THIOGLYCOLATEETHANOL, 2-AMINO-, MERCAPTOACETATE (SALT)
10 more reported names
RefChem:819297ETHANOLAMINE THIOGLYCOLATE [INCI]UNII-263SH5220TEthanolamine thioglycolate (ca. 85% in water)2-aminoethanol,2-sulfanylacetic acidEthanolamine MercaptoacetateXTJCJAPNPGGFED-UHFFFAOYSA-NAS-75819Sulfanylacetic acid--2-aminoethan-1-ol (1/1)Ethanolamine thioglycolate (~85% in water), AldrichCPR
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match160430

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H290 (39.1%): May be corrosive to metals [Warning Corrosive to Metals]; H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]; H315 (60.9%): Causes skin irritation [Warning Skin corrosion/irritation]; H317 (39.1%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H319 (60.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P234, P261, P264, P264+P265, P270, P272, P280, P301+P316, P302+P352, P305+P351+P338, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P390, P405, P406, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 64 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H312: Harmful in contact with skin [Warning Acute toxicity, dermal]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H330: Fatal if inhaled [Danger Acute toxicity, inhalation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Precautionary Statement Codes: P260, P261, P264, P264+P265, P270, P271, P272, P280, P284, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P317, P319, P320, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Cosmetic Ingredient Review Conclusion: Based on the available data, the CIR Expert Panel concluded that ... Ethanolamine Thioglycolate is safe for use in hair straighteners, permanent waves, tonics, dressings, and so forth, wave sets, other non-coloring hair products, and hair dyes and colors, as described in this safety assessment, at concentrations up to 15.2% (as Thioglycolic Acid). Hairdressers should avoid skin contact and minimize consumer skin exposure. Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 29820-13-1
CAS 29820-13-1PubChem CID 22039

(2-(Mercapto-kappaS)acetato(2-)-kappaO)calcium

IUPAC name
calcium 2-sulfidoacetate
Molecular formula
C2H2CaO2S
Molecular weight
130.18 g/mol
Exact mass
129.9401413 Da
Topological polar surface area
41.1 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
3
Covalent units
2
Defined stereocentres
0

Also known as

Calcium, (mercaptoacetato(2-)-O,S)-Calcium, [mercaptoacetato(2-)-O,S]-(Mercaptoacetato(2-)-O,S)calciumMercaptoacetic acid, monocalcium saltCalcium, (2-(mercapto-kappaS)acetato(2-)-kappaO)-RefChem:395121253-511-8Calcium thioglycolate (1:1)
12 more reported names
Calcium sulphidoacetatecalcium;2-sulfidoacetateAcetic acid, mercapto-, calcium salt (1:1)Thioglycolic acid calcium saltAcetic acid, 2-mercapto-, calcium salt (1:1)EINECS 249-881-5calcium sulfidoacetateC2H2CaO2SEC 249-881-5Mercaptoacetic Acid Calcium SaltQVCFQEFEMBCIOI-UHFFFAOYSA-LDB-369920
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 34452-51-2
CAS 34452-51-2PubChem CID 23688957

Potassium Thioglycolate

IUPAC name
potassium 2-sulfanylacetate
Molecular formula
C2H3KO2S
Molecular weight
130.21 g/mol
Exact mass
129.94908199 Da
Topological polar surface area
41.1 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Covalent units
2
Defined stereocentres
0

Also known as

Potassium 2-mercaptoacetateAcetic acid, mercapto-, monopotassium saltUNII-XP5WZO5W6HXP5WZO5W6HEINECS 252-038-4Acetic acid, 2-mercapto-, potassium salt (1:1)EC 252-038-4Mercaptoacetic acid, monopotassium salt
12 more reported names
RefChem:175626POTASSIUM THIOGLYCOLATE [INCI]252-038-4potassium;2-sulfanylacetatePotassium mercaptoacetatepotassium sulfanylacetatepotassium,2-sulfanylacetatePotassium2-mercaptoacetateC2H3KO2SHYTYHTSMCRDHIM-UHFFFAOYSA-MDB-371697Mercaptoacetic acid potassium, 40 to 44% aqueous solution
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 367-51-1
CAS 367-51-1PubChem CID 23690444

Sodium Thioglycolate

IUPAC name
sodium 2-sulfanylacetate
Molecular formula
C2H3NaO2S
Molecular weight
114.10 g/mol
Exact mass
113.97514479 Da
Topological polar surface area
41.1 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
3
Covalent units
2
Defined stereocentres
0

Also known as

Sodium mercaptoacetateMercaptoacetic acid sodium saltThioglycolate sodiumSodium thioglycollateMercaptoacetic acid, sodium saltsodium sulfanylacetateSodium 2-mercatoethanoateThioglycollic acid, sodium salt
16 more reported names
Acetic acid, mercapto-, monosodium saltThioglycolic acid, sodium saltCCRIS 4874USAF EK-5199EINECS 206-696-4EINECS 253-166-3Thioglycolic acid sodium saltUNII-D94M78P69VCHEBI:86481SODIUM THIOGLYCOLATE [II]SODIUM THIOGLYCOLATE [MI]EC 206-696-4SODIUM THIOGLYCOLATE (II)Sodium 2sulfanylacetateSodium 2mercatoethanoateTHIOGLYCOLATESODIUM
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 38337-95-0
CAS 38337-95-0PubChem CID 3084699

mercaptoacetic acid, strontium salt

IUPAC name
strontium 2-sulfanylacetic acid
Molecular formula
C2H4O2SSr+2
Molecular weight
179.74 g/mol
Exact mass
179.89881279 Da
Topological polar surface area
38.3 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Covalent units
2
Defined stereocentres
0

Also known as

EINECS 253-888-9RefChem:156554YDYVEEZRHSAYMD-UHFFFAOYSA-N
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 5421-46-5
CAS 5421-46-5PubChem CID 21534

Ammonium Thioglycolate

Ammonium thioglycolate is an organic ammonium salt having thioglycolate(1) as the counterion. Also known as perm salt, it has use in perming hair. It has a role as an allergen and a reducing agent. It contains a thioglycolate(1-). ChEBI

IUPAC name
azanium 2-sulfanylacetate
Molecular formula
C2H7NO2S
Molecular weight
109.15 g/mol
Exact mass
109.01974964 Da
Topological polar surface area
42.1 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Covalent units
2
Defined stereocentres
0

Also known as

Ammonium mercaptoacetateThioglycolic acid ammonium saltThiofaco A-50Acetic acid, mercapto-, monoammonium saltAmmonium thioglycollateUSAF MO-2ammonium sulfanylacetateHSDB 7167
16 more reported names
Thioglycollic acid, ammonium saltNSC 6954UNII-6P9E788VZZEINECS 226-540-9Mercaptoacetic acid, monoammonium salt6P9E788VZZAI3-26246Acetic acid, 2-mercapto-, ammonium salt (1:1)CHEBI:156555EC 226-540-9NSC-6954AMMONIUM THIOGLYCOLATE [HSDB]Thiofaco A50Ammonium thiogylcollateRefChem:112211Thiogylcollic acid, ammonium salt
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 63592-16-5
CAS 63592-16-5PubChem CID 22027387

Magnesium Thioglycolate

IUPAC name
magnesium bis(2-sulfanylacetate)
Molecular formula
C4H6MgO4S2
Molecular weight
206.5 g/mol
Exact mass
205.9557927 Da
Topological polar surface area
82.3 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
6
Covalent units
3
Defined stereocentres
0

Also known as

UNII-8E96N0WA3XEINECS 264-358-18E96N0WA3XMAGNESIUM, BIS(MERCAPTOACETATO-O,S)-, (T-4)-MAGNESIUM, BIS((MERCAPTO-.KAPPA.S)ACETATO-.KAPPA.O)-, (T-4)-MAGNESIUM, BIS(2-(MERCAPTO-.KAPPA.S)ACETATO-.KAPPA.O)-, (T-4)-RefChem:155278MAGNESIUM THIOGLYCOLATE [INCI]
6 more reported names
MAGNESIUM, BIS((MERCAPTO-KAPPAS)ACETATO-KAPPAO)-, (T-4)-MAGNESIUM, BIS(2-(MERCAPTO-KAPPAS)ACETATO-KAPPAO)-, (T-4)-264-358-1Bis(mercaptoacetato-O,S)magnesiumMagnesium 2-mercaptoacetateMagnesium bis(sulfanylacetate)
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 65208-41-5
CAS 65208-41-5PubChem CID 56840831

Calcium sulfidoacetate--water (1/1/3)

IUPAC name
calcium;2-sulfidoacetate;trihydrate
Molecular formula
C2H8CaO5S
Molecular weight
184.23 g/mol
Exact mass
183.9718354 Da
Topological polar surface area
44.1 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
6
Covalent units
5
Defined stereocentres
0

Also known as

RefChem:331596C2H8CaO5SUM6R6Q3WPX
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 68-11-1
CAS 68-11-1PubChem CID 1133

Thioglycolic Acid

Thioglycolic acid is a sulfur-containing carboxylic acid. It is a conjugate acid of a thioglycolate(1-). ChEBI

IUPAC name
2-sulfanylacetic acid
Molecular formula
C2H4O2S
Molecular weight
92.12 g/mol
Exact mass
91.99320054 Da
XLogP3
0.1
Topological polar surface area
38.3 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

mercaptoacetic acid2-Mercaptoacetic acid2-Thioglycolic acidThioglycollic acidAcetic acid, mercapto-Sulfanylacetic acidThiovanic acidMercaptoessigsaeure
16 more reported names
Glycolic acid, thio-USAF CB-35Acide thioglycoliqueGlycolic acid, 2-thio-Mercaptoethanoic acidKyselina thioglykolovaKyselina merkaptooctovaalpha-Mercaptoacetic acidNSC-18947857H94KHMCHEBI:300652-mercaptoethanoic acidRefChem:897804200-677-4Acetic acid, 2-mercapto-mercapto acetic acid
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 814-71-1
CAS 814-71-1PubChem CID 13141

Calcium Thioglycolate

IUPAC name
calcium bis(2-sulfanylacetate)
Molecular formula
C4H6CaO4S2
Molecular weight
222.3 g/mol
Exact mass
221.9333419 Da
Topological polar surface area
82.3 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
6
Covalent units
3
Defined stereocentres
0

Also known as

Acetic acid, mercapto-, calcium salt (2:1)EbacreamDepilCalcium thioglycollateCalcium mercaptoacetateJullyVikorCalcium bis(mercaptoacetate)
16 more reported names
Acetic acid, 2-mercapto-, calcium salt (2:1)Mercaptoacetic acid calcium derivativeRefChem:122917Secret Dig Hair Removal FoamSecret Dig hair removal spray foamSecret Dig Hair Removal Foam SpraySecret Dig hair removal spray. foam212-402-5249-881-5SurgexCalcium 2-mercaptoacetatecalcium;2-sulfanylacetateUNII-J96129652NEINECS 212-402-5HSDB 1962calcium bis(sulfanylacetate)
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

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Cosmetic Ingredient Review safety assessments

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Independent expert review considered by FDA; not a government approval or binding market rule

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FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

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ILO/WHO International Chemical Safety Cards

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International occupational chemical-safety reference; not cosmetic-use approval

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Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

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NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

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OECD eChemPortal

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Discovery gateway; each linked authority remains responsible for its data

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Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

Open official Decision