Official EU label nameGlossary entry 26616
SODIUM FLUORIDE
This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.
Global evidence snapshot
The resolved identity has matching regulatory evidence in 7 of 13 indexed market datasets: 6 country records and 1 EU Annex records. Every result and evidence gap is listed below.
Markets checked
13
Markets with evidence
7
Evidence gaps
6
Resolved identifiers
7
Resolved substance identity
CAS:7681-49-416984-48-81333-83-17789-75-57783-47-310163-15-2
EC:231-667-8
Ingredient index records:
SODIUM FLUORIDE
Ph. Eur. name: natrii fluoridum
Cosmetic functions: ANTIPLAQUE, ORAL CARE
Sodium fluoride
Inventory restriction note: III/31
8 matched or reported names
SODIUM FLUORIDEsodium fluoridenatrii fluoridumSodium fluorideSodium FluorideFluoride containing substancesSodium fluoride Sodium fluoride CAS No 7681-49-4Sodium fluoride (CAS No. 7681-49-4)
Regulatory evidence in all 13 markets
Open each matched record for its scope, concentration, conditions, warnings and official source version.
Swipe or scroll horizontally to see dataset coverage and next actions.
| Market | Result | Records | Dataset | Meaning / next action |
|---|---|---|---|---|
| European Union EU | Restricted | 1Open record 1 | Complete annex dataset Regulation (EC) 1223/2009 consolidated to 1 May 2026 | Review every linked record and exact conditions. |
| Great Britain GB | Restricted | 1Open record 1 | Complete consolidated annex dataset GB retained Regulation 1223/2009 schedules, effective 15 August 2026 | Review every linked record and exact conditions. |
| Canada CA | Restricted | 1Open record 1 | Complete Hotlist snapshot Health Canada Cosmetic Ingredient Hotlist, 13 August 2025 | Review every linked record and exact conditions. |
| New Zealand NZ | Restricted | 1Open record 1 | Complete schedules dataset Cosmetic Products Group Standard schedules effective 1 January 2026 | Review every linked record and exact conditions. |
| ASEAN ASEAN | Restricted | 1Open record 1 | Complete regional annex dataset ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026 | Review every linked record and exact conditions. |
| China CN | No local match | 0 | Complete prohibited catalogues plus official-source workflow NMPA 2021 banned catalogues plus dynamic IECIC List I/List II system current since 2025 | IECIC listing is not blanket approval; absence may require the new cosmetic ingredient route, and restrictions are checked separately. |
| Japan JP | No local match | 0 | Complete Standards appendices dataset MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshot | The Japanese text and subsequent notices are canonical; no local match is not a product-compliance conclusion. |
| South Korea KR | No local match | 0 | Complete current appendix dataset MFDS Notice 2026-19, effective 18 March 2026 | Korean source wording is canonical and other positive lists/notices may still apply to the formulation. |
| United States US | No local match | 0 | Complete enumerated federal ingredient rules eCFR Title 21 issue date 27 August 2026 | FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety. |
| Australia AU | No local match | 0 | Complete cosmetic-relevant Poisons Standard subset plus official workflow Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026 | An AICIS Inventory match is not cosmetic approval; no Inventory match can indicate a new, exempted, reported or confidential introduction. |
| Brazil BR | No local match | 0 | Complete prohibited dataset plus current restricted-list workflow ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026 | RDC 1.030/2026 amends rather than replaces the prohibited baseline, and the second restricted-list revision was still under consultation in July 2026. |
| India IN | Restricted | 1Open record 1 | Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4 Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022) | Review every linked record and exact conditions. |
| Saudi Arabia SA | Restricted | 1Open record 1 | Complete official list index SFDA live prohibited/restricted lists, snapshot 30 August 2026 | Review every linked record and exact conditions. |
No market rows match this filter.
Matching market records and conditions
Great Britain
GB retained Regulation 1223/2009 schedules, effective 15 August 2026Canada
Health Canada Cosmetic Ingredient Hotlist, 13 August 2025New Zealand
Cosmetic Products Group Standard schedules effective 1 January 2026ASEAN
ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026India
Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022)Saudi Arabia
SFDA live prohibited/restricted lists, snapshot 30 August 2026Exact Annex II–VI evidence
Annex IIIentry 31
Open full regulatory recordSodium fluoride
Product scope: Oral products
Maximum concentration: 0,15 % calculated as F. When mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0,15 %
Warnings: Contains sodium fluoride For any toothpaste with compounds containing fluorine in a concentration of 0.1 to 0.15% calculated as F unless it is already labelled as contra-indicated for children (e.g. "for adult use only") the following labelling is obligatory: "Children of 6 years and younger: use …
Chemical identity and properties
CAS 10163-15-2PubChem CID 24266
Sodium Monofluorophosphate
Sodium fluorophosphate, commonly abbreviated MFP, is an inorganic compound with the chemical formula Na2PO3F. Typical for a salt, MFP is odourless, colourless, and water-soluble. This salt is an ingredient in toothpastes. It has a role as an antibacterial agent. It is an inorganic phosphate and an inorganic sodium salt. — ChEBI
- IUPAC name
- disodium;fluoro-dioxido-oxo-lambda5-phosphane
- Molecular formula
- FNa2O3P
- Molecular weight
- 143.950 g/mol
- Exact mass
- 143.93644758 Da
- Topological polar surface area
- 63.2 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 4
- Covalent units
- 3
- Defined stereocentres
- 0
Also known as
Phosphorofluoridic acid, disodium saltExtra-Strength AimC810JCZ56QNSC-248bridentsmilecareRegularRembrandt
16 more reported names
SaliveaBarbieOrazenPriyalSparkleFreshMyntSmilepurple toothSmartMouthAGToothpasteCloveden ToothDeCureFinefra SilverGlancure ToothHello WhiteningKroger CompanyNatures Promise
External database identifiers
- ChEBI:CHEBI:86431
- ChEMBL:CHEMBL1908359
- EPA DTXSID:DTXSID70872554
- PubMed:1234
Evidence from additional scientific databases
EMBL-EBI ChEBI
Exact identifier matchCHEBI:86431
sodium fluorophosphate
Sodium fluorophosphate, commonly abbreviated MFP, is an inorganic compound with the chemical formula Na2PO3F. Typical for a salt, MFP is odourless, colourless, and water-soluble. This salt is an ingredient in toothpastes.
- Formula
- FO3P.2Na
- Average mass
- 143.949 g/mol
- Monoisotopic mass
- 143.93645 Da
- Formal charge
- 0
- inorganic sodium salt — is a (CHEBI:38702)
- inorganic phosphate — is a (CHEBI:24838)
- antibacterial agent — has role (CHEBI:33282)
- antibacterial agent — has role (CHEBI:33282)
- inorganic sodium salt — is a (CHEBI:38702)
- inorganic phosphate — is a (CHEBI:24838)
Additional curated names
disodium phosphorofluoridatedisodium fluorophosphatedisodium monofluorophosphateNSC-248Phosphorofluoridic acid, disodium saltSodium fluorophosphatesodium monofluorophosphateSodium phosphorofluoridate
Cross-references from this source
- CAS: 10163-15-2 — KEGG DRUG
- CAS: 10163-15-2 — ChemIDplus
- REGISTRY_NUMBER: 11335196 — Reaxys
- MANUAL_X_REF: D05864 — KEGG DRUG
- MANUAL_X_REF: Sodium_monofluorophosphate — Wikipedia
Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2015-07-24. Retrieved: 2026-08-31. Open source record
NIH PubChem PUG-View
Exact identifier match24266
Attributed physical-property, hazard, environmental and use annotations.
- Physical Description: White powder; [Pfaltz and Bauer MSDS] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Note: This chemical does not meet GHS hazard criteria for 1.4% (1 of 72) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302 (91.7%): Harmful if swallowed [Warning Acute toxicity, oral]; H315 (11.1%): Causes skin irritation [Warning Skin corrosion/irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264, P270, P280, P301+P317, P302+P352, P321, P330, P332+P317, P362+P364, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 72 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 1 of 72 reports by companies.; There are 4 notifications provided by 71 of 72 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]; H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]; H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]; H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 8 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| EMBL-EBI ChEBI | Exact match | 2026-08-31 |
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 1333-83-1PubChem CID 219061
Sodium hydrogen difluoride
Sodium bifluoride is a white crystalline solid. It is soluble in water. It is corrosive to tissue. It is used as a preservative for anatomical and zoological specimens, in metal plating and for many other uses. — CAMEO Chemicals
- IUPAC name
- sodium;fluoride;hydrofluoride
- Molecular formula
- F2HNa
- Molecular weight
- 61.9946 g/mol
- Exact mass
- 61.99440064 Da
- Topological polar surface area
- 0.0 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 2
- Covalent units
- 3
- Defined stereocentres
- 0
Also known as
Sodium bifluorideSodium acid fluorideSodium hydrogen fluorideSodium hydrogendifluorideCaswell No. 747AFluoruro acido de sodioHSDB 5820Fluorure acide de soodium
16 more reported names
Fluoruro acido de sodio [Spanish]Fluorure acide de soodium [French]EINECS 215-608-3Sodium fluoride (NaF), mixt. contgUN2439Sodium fluoride-hydrofluoric acid mixtEPA Pesticide Chemical Code 0752013W2KK83V5GHydrofluoric acid, mixt. with sodium fluorideSODIUM BIFLUORIDE [MI]EC 215-608-3Hydrofluoric acid, mixt. with sodium fluoride (NaF)SODIUM HYDROGEN DIFLUORIDE [HSDB]Fluoruro acido de sodio (Spanish)SODIUM DIFLUORIDESODIUM BIFLUORIDE, (SOLID)
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 16984-48-8PubChem CID 28179
Fluoride Ion
Fluoride is a halide anion and a monoatomic fluorine. It is a conjugate base of a hydrogen fluoride. — ChEBI
- IUPAC name
- fluoride
- Molecular formula
- F-
- Molecular weight
- 18.99840316 g/mol
- Exact mass
- 18.998403162 Da
- XLogP3
- 0.6
- Topological polar surface area
- 0.0 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 1
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
Fluoride ion(1-)PerfluorideFluorine ionFluoride(1-)Fluoride ion(F-)Fluorine ion(1-)Drinking water, fluoride treatedF-
16 more reported names
UNII-Q80VPU408OQ80VPU408OFLURORIDE-IONFLUORINE ION(F1-)CHEBI:17051F(-)Fluorine-RefChem:5836Topex Neutral pH Fluoride GelTopex Neutral pH Fluoride GelMintTopex Neutral pH Fluoride GelStrawberryFLUORIDE STANDARDCHEMBL1362Fluoride dustFluoridesFluoride as dust
External database identifiers
- ChEBI:CHEBI:17051
- ChEMBL:CHEMBL1362
- EPA DTXSID:DTXSID9049617
- PubMed:40571328
- PubMed:39012504
- PubMed:38676876
- PubMed:37482551
- PubMed:37269894
- PubMed:37269891
- PubMed:36063856
- PubMed:35714946
- PubMed:34780879
- PubMed:34227456
- PubMed:34051202
- PubMed:33982124
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 7681-49-4PubChem CID 5235
Sodium Fluoride
Sodium fluoride is a metal fluoride salt with a Na(+) counterion. It has a role as a mutagen. — ChEBI
- IUPAC name
- sodium fluoride
- Molecular formula
- FNa
- Molecular weight
- 41.9881724 g/mol
- Exact mass
- 41.98817244 Da
- Topological polar surface area
- 0.0 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 1
- Covalent units
- 2
- Defined stereocentres
- 0
Also known as
Sodium fluoride (NaF)Fluoride, sodiumFlorocidPerganteneZymafluorPediaflorOssinSodium flouride
16 more reported names
FluonatrilFluoridentSodium monofluorideVilliaumiteAntibulitFloridineFluoradayFluorolFlursolKaridiumKoreberonLiquiflurOssalinXaridiumFluraLuride
External database identifiers
- ChEBI:CHEBI:28741
- ChEMBL:CHEMBL1528
- EPA DTXSID:DTXSID2020630
- PubMed:41830162
- PubMed:39910692
- PubMed:39613240
- PubMed:39012504
- PubMed:38823497
- PubMed:38342390
- PubMed:38036095
- PubMed:37739047
- PubMed:37694959
- PubMed:37245782
- PubMed:37121298
- PubMed:37105417
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
- IUPAC name
- difluorotin
- Molecular formula
- F2Sn
- Molecular weight
- 156.71 g/mol
- Exact mass
- 157.899009 Da
- Topological polar surface area
- 0.0 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 2
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
STANNOUS FLUORIDETin difluorideTin bifluorideTin Fluoride (SnF2)EasygelStancareStanideCrest
16 more reported names
Iradicar SnF2Iradicav SnF2King's Gel-TinCap-Tin MouthrinseStop Home TreatmentIradicar Stannous FluorideStannous fluoride (SnF2)Stannous fluoride (USP)Stannous fluoride [USP]BurkhartEvernamelFluoridexGingimedOmnigelStangardWhitening
External database identifiers
- ChEBI:CHEBI:135933
- EPA DTXSID:DTXSID6064822
- PubMed:27838508
- PubMed:26030135
- PubMed:24693625
- PubMed:20662911
- PubMed:19189400
- PubMed:17645550
- PubMed:13579125
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 7789-75-5PubChem CID 84512
Calcium Fluoride
Calcium difluoride is an inorganic calcium salt and a calcium salt. — ChEBI
- IUPAC name
- calcium difluoride
- Molecular formula
- CaF2
- Molecular weight
- 78.07 g/mol
- Exact mass
- 77.9593972 Da
- Topological polar surface area
- 0.0 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 2
- Covalent units
- 3
- Defined stereocentres
- 0
Also known as
FluorsparCHEBI:35437Calc FluorFluoride, CalciumCalc Fluor 6XCalc Fluor 12XCalc Fluor 30XAmethyst 8104
16 more reported names
Calc Fluor 200XFluorite 8118CALCAREA FLOURCALCAREA FLUORRefChem:5634TONICPET 1Calcarea Fluorica 8001CALCAREA FLUORICA 6X232-188-7Bestmade Natural Products Calc FluorJacksons Cell Salts CALC FLUOR 6XJacksons Cell Salts CALC FLUOR 6X 1D-121Calcarea FluoricaCalcium fluoratumCalcium fluoride (CaF2)
External database identifiers
- ChEBI:CHEBI:35437
- EPA DTXSID:DTXSID4050487
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Additional authoritative substance research
Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight
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Official source and scope
Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.
Open official Decision