Official EU label nameGlossary entry 26170

SIMETHICONE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Evidence gaps

Resolved identifiers

Resolved substance identity

CAS:8050-81-5

Ingredient index records:

SIMETHICONE

Cosmetic functions: ANTIFOAMING, HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Silica, hydrated, compounds with poly(dimethylsiloxane)

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2 matched or reported names

SIMETHICONEsimethicone

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name SIMETHICONE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 8050-81-5

CAS 8050-81-5PubChem CID 6433516

Simethicone

Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed. Simethicone has been in use since the 1940s but was granted FDA approval in 1952. — DrugBank

IUPAC name: dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane

Molecular formula: C6H18O4Si3
Molecular weight: 238.46 g/mol
Exact mass: 238.05128865 Da
Topological polar surface area: 52.6 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 4
Covalent units: 2
Defined stereocentres: 0

Also known as

Sentry SimethiconeMylanta Gas ReliefMylicon Infant's DropsSentry Simethicone EmulsionRefChem:8863423,3,5,5-tetramethyl-2,4-dioxa-3,5-disilahexane; silanedione617-098-1Simethicon

8 more reported names

Simethicone(200)Simethicone(500)SIMETICONEC6H18O4Si3Simethicone-Viscosity 500cPAMTWCFIAVKBGOD-UHFFFAOYSA-NDA-77848dioxosilane;methoxy-dimethyl-trimethylsilyloxy-silane

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External database identifiers

PubMed:20003095
PubMed:7352543

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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