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Official EU label nameGlossary entry 26161

SILYBUM MARIANUM CALLUS EXTRACT

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
2

Resolved substance identity

CAS:84604-20-6
EC:283-298-7
Ingredient index records:
SILYBUM MARIANUM CALLUS EXTRACT
Cosmetic functions: SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

Silybum Marianum Callus Extract is the extract of the callus of Silybum marianum grown in culture, Asteraceae.

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1 matched or reported name
SILYBUM MARIANUM CALLUS EXTRACT

Official name structure and source evidence

This section separates facts supplied by external records from structure derived only from the exact official label wording.

Structured interpretation of the official EU INCI label

Matchedlabel-analysis-v1 · EU 2025/1175

The official label identifies a biological source material and its stated preparation or plant part.

Identity type inferred from wording
biological_material
Preparation or form stated in the name
CALLUS EXTRACT, EXTRACT
Parts stated in the name
CALLUS
Scientific-name candidates requiring taxonomy verification:
Silybum marianum

This structure is derived only from the official label wording. It does not establish composition, concentration, chemical equivalence, safety or regulatory permission.

Open evidence source

Verified source-organism taxonomy

Scientific names embedded in the official INCI label were resolved by exact-name search against an immutable Catalogue of Life release.

2026-07-17 XR

Silybum marianum

accepted

(L.) Gaertn.

Rank
species
Kingdom
Plantae
Family
Asteraceae
Genus
Silybum
COL ID
6YPNF
milk-thistleEchte Mariendistel (DE); Milk ThistleMary's ThistleGewöhnliche MariendistelMarian thistleSt. Mary's Thistle (EN); Caro mariano (ES)DisseldSt. Mary's thistle
Open Catalogue of Life record

Catalogue of Life 2026-07-17 XR · DOI 10.48580/dgykv · CC BY 4.0.

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name SILYBUM MARIANUM CALLUS EXTRACT.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

Check the markets and their sourcesSearch every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 84604-20-6
CAS 84604-20-6PubChem CID 5213

Silymarin

3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-3,4-dihydro-2H-1-benzopyran-4-one is a flavonolignan. — ChEBI

IUPAC name
3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one
Molecular formula
C25H22O10
Molecular weight
482.4 g/mol
Exact mass
482.12129689 Da
XLogP3
2.4
Topological polar surface area
155.0 Ų
Hydrogen-bond donors
5
Hydrogen-bond acceptors
10
Covalent units
1
Defined stereocentres
0

Also known as

Silimarin3,5,7-trihydroxy-2-(3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl)-2,3-dihydrochromen-4-oneRefChem:931755613-830-9SilybinFlavobin Spofa(2S)-3,5,7-trihydroxy-2-[(2S,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one(2R,3R)-3,5,7-trihydroxy-2-[(2R)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one
16 more reported names
Silymarin (>80%)Silibin3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxy-phenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]chroman-4-one3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-3,4-dihydro-2H-1-benzopyran-4-one4H-1-Benzopyran-4-one,2-[2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-SR-01000000093Silybin;Silibinin A;Silymarin ISilmyarinSilibinin BSilibinin, INN3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydro-4H-chromen-4-oneSilybin (7CI)Silybum substance E6Silybin(Mixture A&B)Silibinin (mixture of Silybin A and Silybin B)Silibinin (NSC 651520)
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External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Other ingredients from the same source

Silybum marianum

milk-thistleMary's ThistleMarian thistle

8 other ingredients in this inventory name the same organism. Sharing a source is not sharing an identity: a leaf extract, a seed oil and a ferment are different materials with different specifications.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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