Official EU label nameGlossary entry 25753

SHIKALKIN

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence

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Markets with evidence

Evidence gaps

Resolved identifiers

Resolved substance identity

CAS:117746-18-6517-88-4517-89-5

EC:610-730-7

Ingredient index records:

SHIKALKIN

Cosmetic functions: COLORANT; SKIN CONDITIONING - MISCELLANEOUS

Shikalkin is the racemic mixture of shikonin and alkannin that conforms generally to the formula:

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1 matched or reported name

SHIKALKIN

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name SHIKALKIN.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 517-88-4

CAS 517-88-4PubChem CID 72521

Alkannin

Alkannin is a hydroxy-1,4-naphthoquinone. — ChEBI

IUPAC name: 5,8-dihydroxy-2-[(1S)-1-hydroxy-4-methylpent-3-enyl]naphthalene-1,4-dione

Molecular formula: C16H16O5
Molecular weight: 288.29 g/mol
Exact mass: 288.09977361 Da
XLogP3: 3.0
Topological polar surface area: 94.8 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 1

Also known as

AnchusinAlkanna RedAnchusa acid075CRZ9995NSC-945245,8-dihydroxy-2-[(1S)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione5,8-dihydroxy-2-((1S)-1-hydroxy-4-methyl-pent-3-enyl)naphthalene-1,4-dione5,8-dihydroxy-2-((1S)-1-hydroxy-4-methylpent-3-enyl)naphthalene-1,4-dione

16 more reported names

RefChem:554083208-245-7(-)-AlkanninAlkannin (VAN)Anchusin (VAN)Alkanna red (VAN)Anchusa acid (VAN)(S)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dioneCHEBI:2578(S)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)-1,4-naphthoquinoneE1035,8-dihydroxy-2-[(1S)-1-hydroxy-4-methylpent-3-en-1-yl]-1,4-dihydronaphthalene-1,4-dioneC.I. Natural Red 20 (VAN)Cerven prirodni 20Cerven prirodni 20 [Czech]UNII-075CRZ9995

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External database identifiers

ChEBI:CHEBI:2578
ChEMBL:CHEMBL28457
EPA DTXSID:DTXSID201029621
PubMed:40389196
PubMed:30924981
PubMed:11408205

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 517-89-5

CAS 517-89-5PubChem CID 479503

Shikonin

Shikonin is a hydroxy-1,4-naphthoquinone. — ChEBI

IUPAC name: 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-enyl]naphthalene-1,4-dione

Molecular formula: C16H16O5
Molecular weight: 288.29 g/mol
Exact mass: 288.09977361 Da
XLogP3: 3.0
Topological polar surface area: 94.8 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 1

Also known as

Isoarnebin 4ShikonineTokyo Violet(R)-(+)-Shikonin(+)-ShikoninNSC 252844CCRIS 64923IK6592UBW

16 more reported names

(+)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinoneC.I. 755351,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-, (R)-1,4-NAPHTHOQUINONE, 5,8-DIHYDROXY-2-(1-HYDROXY-4-METHYL-3-PENTENYL)-, (+)-NSC-2528441,4-naphthalenedione, 5,8-dihydroxy-2-((1r)-1-hydroxy-4-methyl-3-pentenyl)-1,4-Naphthalenedione, 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-pentenyl]-5,8-dihydroxy-2-((1R)-1-hydroxy-4-methyl-3-penten-1-yl)-1,4-naphthalenedione5,8-DIHYDROXY-2-((1R)-1-HYDROXY-4-METHYLPENT-3-ENYL)NAPHTHALENE-1,4-DIONE5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-penten-1-yl]-1,4-naphthalenedioneshikonin, (+)-RefChem:487985,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthalenedione610-730-71,4-naphthalenedione, 5,8-dihydroxy-2-((1R)-1-hydroxy-4-methyl-3-penten-1-yl)-2-((1R)-1-hydroxy-4-methyl-3-pentenyl)-5,8-dihydroxy-1,4-naphthoquinone

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External database identifiers

ChEBI:CHEBI:81068
ChEMBL:CHEMBL9470
EPA DTXSID:DTXSID30199653
PubMed:12937000

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

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Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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