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Official EU label nameGlossary entry 25458

SCOPARONE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
2

Resolved substance identity

CAS:120-08-1
EC:204-369-0
Ingredient index records:
SCOPARONE
Cosmetic functions: ANTIOXIDANT

6,7-Dimethoxycoumarin,6,7-Dimethylesculetin,2H-1-Benzopyran-2-one, 6,7-Dimethoxy-

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1 matched or reported name
SCOPARONE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name SCOPARONE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

Check the markets and their sourcesSearch every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 120-08-1
CAS 120-08-1PubChem CID 8417

Scoparone

Scoparone is a member of the class of coumarins that is esculetin in which the two hydroxy groups at positions 6 and 7 are replaced by methoxy groups. It is a major constituent of the Chinese herbal medicine Yin Chen Hao, and exhibits a variety of pharmacological activities such as anti-inflammatory, anti-allergic, and anti-tumor activities. It has a role as an antihypertensive agent, an antilipemic drug, an immunosuppressive agent, an anti-allergic agent, an anti-inflammatory agent and a plant metabolite. It is a member of coumarins and an aromatic ether. It is functionally related to an esculetin. — ChEBI

IUPAC name
6,7-dimethoxychromen-2-one
Molecular formula
C11H10O4
Molecular weight
206.19 g/mol
Exact mass
206.05790880 Da
XLogP3
1.9
Topological polar surface area
44.8 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

6,7-DIMETHOXYCOUMARIN6,7-DimethylesculetinEscoparoneScoparon6,7-Dimethoxy-2H-chromen-2-oneEsculetin dimethyl etherAesculetin dimethyl etherScopoletin methyl ether
16 more reported names
o-Methylscopoletin6,7-Dimethoxy-2H-1-benzopyran-2-oneo-Methylisoscopoletino,o-Dimethylesculetin6,7-Dimethoxy-Coumarin6,7-Dimethoxybenzopyran-2-oneEsculetin 6,7-dimethyl etherH5841PDT4YCHEBI:9055RefChem:181956204-369-06,7-Dimethoxy-2-benzopyrone2H-1-Benzopyran-2-one, 6,7-dimethoxy-Dimethyl esculetinCoumarin, 6,7-dimethoxy-Benzopyran-2-one, 6,7-dimethoxy-
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match8417

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]; H319 (97.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P264, P264+P265, P270, P280, P301+P316, P305+P351+P338, P321, P330, P337+P317, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 42 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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