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Official EU label nameGlossary entry 24180

RHEIN

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
1

Resolved substance identity

CAS:478-43-3
Ingredient index records:
RHEIN
Cosmetic functions: ANTIMICROBIAL

2-Anthracenecarboxylic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-,Cassic Acid,Rheic Acid

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1 matched or reported name
RHEIN

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name RHEIN.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 478-43-3
CAS 478-43-3PubChem CID 10168

Rhein

Rhein is a dihydroxyanthraquinone. — ChEBI

IUPAC name
4,5-dihydroxy-9,10-dioxoanthracene-2-carboxylic acid
Molecular formula
C15H8O6
Molecular weight
284.22 g/mol
Exact mass
284.03208797 Da
XLogP3
2.2
Topological polar surface area
112.0 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
0

Also known as

MonorheinCassic acidRhubarb YellowRheic acid4,5-Dihydroxyanthraquinone-2-carboxylic acidChrysazin-3-carboxylic acid1,8-Dihydroxyanthraquinone-3-carboxylic acid9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid
16 more reported names
YM64C2P6UX2-Anthroic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-NSC-386291,8-dihydroxy-3-carboxyl-9,10-anthraquinoneRefChem:882948207-521-44,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid1,8-Dihydroxy-3-carboxyanthraquinoneNSC 38629C15H8O6Rhein (Standard)2-Anthracenecarboxylic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-4,5-Dihydroxy-2-anthraquinonecarboxylic acid4,5-DiOH-anthraquinone-2-COOHRhein (1,8-dihydroxy-3-carboxyl anthraquinone)9,10-Dihydro-4,5-dihydroxy-9,10-dioxoanthracene-2-carboxylic acid
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External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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