Is RHEIN safe to use in EU cosmetics?

RHEIN is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 478-43-3?

CAS 478-43-3 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

InventoryRef 9188618/11/2014

RHEIN

Q: How do I check if my formula contains RHEIN?

Use the INCI Checker tool on CosIng Checker to paste your full ingredient list and scan it against all EU annex records and allergen flags in one step.

2-Anthracenecarboxylic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-,Cassic Acid,Rheic Acid

RHEIN is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

INCI Checker Search similar

Inventory details for RHEIN

INCI name

RHEIN

Description

2-Anthracenecarboxylic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-,Cassic Acid,Rheic Acid

Annex records for RHEIN

Browse

Browse EU annexes

Explore Annex II–VI to see which substances are prohibited, restricted or permitted under specific conditions.

Search annex entries

Search the annex database for entries matching RHEIN or related substances.

Key data

CAS

478-43-3

—

Restriction

—

Function

ANTIMICROBIAL

How RHEIN appears in the CosIng inventory

The CosIng inventory lists RHEIN as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

RHEIN is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

RHEIN is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, RHEIN carries the following function designation(s):

ANTIMICROBIAL

CAS 478-43-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

View CAS records

Use the INCI Checker tool to paste your full ingredient list and scan it against all EU annex records and allergen flags in one step.

Open INCI Checker

Source note for RHEIN

This page reproduces the CosIng inventory entry for RHEIN from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research RHEIN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

View sources View updates

Tools & next steps

Check your formula

Scan a full INCI list to detect RHEIN and any linked EU annex restrictions or allergen flags.

INCI Checker

Search similar ingredients

Find other inventory ingredients and annex entries related to RHEIN, its identifiers or nearby name variants.