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Official EU label nameGlossary entry 23257

PROPAFENONE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
1

Resolved substance identity

CAS:54063-53-5
Ingredient index records:
PROPAFENONE

1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one

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1 matched or reported name
PROPAFENONE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name PROPAFENONE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 54063-53-5
CAS 54063-53-5PubChem CID 4932

Propafenone

Propafenone is an aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias. It has a role as an anti-arrhythmia drug. It is a secondary alcohol, a secondary amino compound and an aromatic ketone. It is a conjugate base of a propafenone(1+). — ChEBI

IUPAC name
1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one
Molecular formula
C21H27NO3
Molecular weight
341.4 g/mol
Exact mass
341.19909372 Da
XLogP3
3.3
Topological polar surface area
58.6 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

PropafenonaPropafenonum1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenylpropan-1-onePropafenon HexalGNF-Pf-45941-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone68IQX3T69U1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one
16 more reported names
CHEBI:636191-Propanone, 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-2-(2'-hydroxy-3'-propylaminopropoxy)-omega-phenylpropiophenone1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-NorfenonPintoformPropafenon MindenRefChem:55924SA79C01BC03258-955-6RythmolPropafenonum [INN-Latin]Propafenona [INN-Spanish]Propafenone (INN)CHEMBL631
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External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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